Is Glyceryl Isostearate safe in cosmetics?
Glyceryl Isostearate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Glyceryl Isostearate
INCI: GLYCERYL ISOSTEARATE
Glyceryl Isostearate (CAS 66085-00-5) is a cosmetic cosmetic ingredient functioning as Emollient / Emulsifier. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 66085-00-5 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient / Emulsifier
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2,3-dihydroxypropyl 16-methylheptadecanoate
InChIKey
ASKIVFGGGGIGKH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel concluded safe in present practices of use (2004, reaffirmed 2020)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Isostearate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
2 property records from structured ingredient metadata.
emulsifier
{"cas_number": "66085-00-5", "ingredient_class": "W/O_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "3.5", "HLB_required_for_oil_phase": "3-5", "emulsion_type_primary": "W/O", "droplet_size_typical_um": "5-10", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "liquid_crystal_formation": "low", "lamellar_phase…
emulsion_hlb
{"hlb_value": "3.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.60-0.80", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "sorbitan_isostearate", "optimal_oil_phase_pct": "58-85", "optimal_water_phase_pct": "15-42", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.0-11.0", "viscosity_build…
Expert Verdict
Expert safety assessment and concern-level summary for Glyceryl Isostearate.
Regulatory Flags
emollient
emulsifier
glyceryl-ester
cosmos-eligible
non-sensitizer
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Glyceryl Isostearate allowed in the EU?
Glyceryl Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glyceryl Isostearate do in cosmetics?
Glyceryl Isostearate functions as: Emollient / Emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 66085-00-5.
Is Glyceryl Isostearate used outside cosmetics?
Glyceryl Isostearate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glyceryl Isostearate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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