Is Glyceryl Glycyrrhetinate safe in cosmetics?
Glyceryl Glycyrrhetinate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Glyceryl Glycyrrhetinate
Also known as: Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, monoester with 1,2,3-propanetriol, (3beta,20beta)-, Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, 2,3-dihydroxypropyl ester, (3-β)-, Glyceryl glycyrrhetate Glyceryl glycyrrhetinate, Glyceryl monoglycyrrhetinate
INCI: GLYCERYL GLYCYRRHETINATE
Glyceryl Glycyrrhetinate (CAS 108916-85-4) is a cosmetic cosmetic ingredient functioning as Emulsifier, skin conditioning (anti-inflammatory via glycyrrhetinic acid moiety). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 108916-85-4 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifier, skin conditioning (anti-inflammatory via glycyrrhetinic acid moiety)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2,3-dihydroxypropyl (2S,4aS,6aR,6aS,6bR,10S,12aS,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
InChIKey
NNYMAFQJECSMTN-YZADGDQXSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — licorice and licorice derivatives are FDA GRAS; CIR Expert Panel concluded glycyrrhetinic acid and its salts/esters are safe for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Glycyrrhetinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Expert Verdict
Expert safety assessment and concern-level summary for Glyceryl Glycyrrhetinate.
Known Synonyms
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, monoester with 1,2,3-propanetriol, (3beta,20beta)-
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, 2,3-dihydroxypropyl ester, (3-β)-
Glyceryl glycyrrhetate Glyceryl glycyrrhetinate
Glyceryl monoglycyrrhetinate
Chemical Function
Emulsifier
Frequently Asked Questions
Is Glyceryl Glycyrrhetinate allowed in the EU?
Glyceryl Glycyrrhetinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glyceryl Glycyrrhetinate do in cosmetics?
Glyceryl Glycyrrhetinate functions as: Emulsifier, skin conditioning (anti-inflammatory via glycyrrhetinic acid moiety). It is classified as a cosmetic ingredient in our database. CAS number: 108916-85-4.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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