Moderate Cosmetic Ingredient SCCS/CIR Reviewed

Glycereth-26

Also known as: Poly(oxy-​1,​2-​ethanediyl)​, α,​α',​α''-​1,​2,​3-​propanetriyltris[ω-​hydroxy-, Glycols, polyethylene, 1,2,3-propanetriyl ether, Glycerol polyoxyethylene ether, Glycerol-ethylene oxide adduct, Glycerol-polyethylene glycol adduct (+13 more)

INCI: GLYCERETH-26

Glycereth-26 (CAS 31694-55-0) is a cosmetic cosmetic ingredient functioning as Humectant. EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 31694-55-0 →

Auto-generated CPSR Part A draft with source citations
Function
Humectant
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C9H20O6
MW
224.25 g/mol
EC Number
500-075-4
PubChem CID
88802
IUPAC Name
2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol
InChIKey
UCYLROVJSUACAD-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR: Insufficient data (2020 tentative report). 437 VCRP formulations. CIR did NOT conclude safe — insufficient data.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Glycereth-26.

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe

data relating to the safety of these ingredients. The Panel concluded that these ingredients are safe in cosmetics in the present practices of use and concentration as described in this safety assessment when formulated to be non-irritating. Keywords Cosmetic Ingredient Review, Expert Panel for Cosme

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

3 property records from structured ingredient metadata.

ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "low-moderate toxicity", "freshwater_toxicity": "moderate persistence", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environm…
humectant
{"cas_number": "31694-55-0", "ingredient_class": "humectant/polyol", "molecular_weight_Da": "1192", "chemical_type": "synthetic_polymer", "water_binding_mechanism": "hydrogen_bonding/hygroscopic", "water_holding_capacity_g_per_g": "0.8-1.1", "hygroscopicity_at_50_RH": "excellent", "hygroscopicity_at_80_RH": "excellent", "NMF_component": "no", "NMF_percentage_natural": "0", "TEWL_reduction_pct": "2…
sensory
{"silky": "medium", "smooth, glides easily": "slippery, wet", "dry-touch, non-greasy": "hydrated, tacky", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.47", "transparent": "transparent", "colorless": "colorless", "excellent": "fair", "light": "light", "synthetic": "synthetic"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance Humectant Plasticizer Softener and conditioner Solvent Surfactant (surface active agent) Viscosity modifier
Regulatory List Membership (3)
EU Restricted for Children (Cosmetics) IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Glycereth-26.

Regulatory Flags

CONTROVERSIAL eu_children_restricted epa_safer_alternative ifra_fragrance

Known Synonyms

Poly(oxy-​1,​2-​ethanediyl)​, α,​α',​α''-​1,​2,​3-​propanetriyltris[ω-​hydroxy- Glycols, polyethylene, 1,2,3-propanetriyl ether Glycerol polyoxyethylene ether Glycerol-ethylene oxide adduct Glycerol-polyethylene glycol adduct Glyceryl polyether 26 α,α',α''-1,2,3-Propanetriyltris[ω-hydroxypoly(oxy-1,2-ethanediyl)] α-Hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) ether with 1,2,3-propanetriol α,α',α''-Propane-1,2,3-triyltris[ω-hydroxypoly(oxyethylene)] alkoxylation reaction product of glycerin as starter and ethylene oxyde (eo) as monomer Glycerol, ethoxylated 1,2,3-Propanetriol, ethoxylated 1,2,3-Propanetriol, polymer with oxirane Adeka Carpol TE 100 Blaunon GL 26 Botanimoist G 26 Carbowax TPEG 990 Conion RG 120

Chemical Function

Solvent Surfactant (surface active agent) Humectant Softener and conditioner Viscosity modifier

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - dental care - toothpaste CEDI SCIL (9/2019) IFRA Transparency inert_ingredient; non_food_use; Pesticides

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Glycereth-26 safe in cosmetics?

Glycereth-26 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by cir.

Is Glycereth-26 allowed in the EU?

Glycereth-26 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycereth-26 do in cosmetics?

Glycereth-26 functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 31694-55-0.

Is Glycereth-26 used outside cosmetics?

Glycereth-26 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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