Is Ginsenoside Rh1 safe in cosmetics?
Ginsenoside Rh1 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ginsenoside Rh1
INCI: GINSENOSIDE RH1
Ginsenoside Rh1 (CAS 63223-86-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-inflammatory metabolite of saponin Re; reduces. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 63223-86-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-inflammatory metabolite of saponin Re; reduces oxazolone-induced dermatitis in mice
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
InChIKey
RAQNTCRNSXYLAH-RFCGZQMISA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR concluded parent ingredients safe as used; not prohibited under 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ginsenoside Rh1.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Ginsenoside Rh1.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GINSENOSIDE RH1
ChEMBL ID
CHEMBL466844
Frequently Asked Questions
Is Ginsenoside Rh1 allowed in the EU?
Ginsenoside Rh1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ginsenoside Rh1 do in cosmetics?
Ginsenoside Rh1 functions as: Skin conditioning, anti-inflammatory metabolite of saponin Re; reduces oxazolone-induced dermatitis in mice. It is classified as a cosmetic ingredient in our database. CAS number: 63223-86-9.
Is Ginsenoside Rh1 used outside cosmetics?
Ginsenoside Rh1 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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