Is Ginsenoside Re safe in cosmetics?
Ginsenoside Re has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ginsenoside Re
INCI: GINSENOSIDE RE
Ginsenoside Re (CAS 52286-59-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning, antioxidant (major protopanaxatriol-type ginsenoside). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 52286-59-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, antioxidant (major protopanaxatriol-type ginsenoside)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
InChIKey
PWAOOJDMFUQOKB-WCZZMFLVSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not prohibited or restricted under 21 CFR; covered under CIR Panax spp. assessment (safe as used, 2015)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ginsenoside Re.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Ginsenoside Re.
Chemical Function
Humectant
Antioxidant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GINSENOSIDE RE
ChEMBL ID
CHEMBL510095
Max Phase
0.5
Frequently Asked Questions
Is Ginsenoside Re allowed in the EU?
Ginsenoside Re EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ginsenoside Re do in cosmetics?
Ginsenoside Re functions as: Skin conditioning, antioxidant (major protopanaxatriol-type ginsenoside). It is classified as a cosmetic ingredient in our database. CAS number: 52286-59-6.
Is Ginsenoside Re used outside cosmetics?
Ginsenoside Re also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ginsenoside Re compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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