NOAEL Studies Cosmetic Ingredient

Germanium Dioxide NOAEL Studies

INCI: GERMANIUM DIOXIDE

CAS: 1310-53-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_inhalation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 >1.42 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=636; Record_ID=acute_inhalation_1287; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID0051653; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=1.42; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID0051653
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =0.335 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15632383:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_31b0043e262c725c919fc2d5d700d105
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 5O6CM4W76A UNII - - - chemical {"approval_status":null,"molecular_formula":"Ge.2O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"5O6CM4W76A"}
openFDA substances FDA UNII substance identifier 5O6CM4W76A UNII - - - chemical {"approval_status":null,"molecular_formula":"Ge.2O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"5O6CM4W76A"}
openFDA substances FDA UNII substance identifier 5O6CM4W76A UNII - - - chemical {"approval_status":null,"molecular_formula":"Ge.2O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"5O6CM4W76A"}
openFDA substances FDA UNII substance identifier 5O6CM4W76A UNII - - - chemical {"approval_status":null,"molecular_formula":"Ge.2O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"5O6CM4W76A"}