Eugenol NOAEL Studies

COSMOS_DB 9 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
COSMOS_DB	NOAEL	638	mg/kg bw/day	rat	oral	728 day	Carcinogenicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	1200	mg/kg bw/day	mouse	oral	735 day	Carcinogenicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	1000	mg/kg bw/day	rat	oral	133 day	Subchronic	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	1400	mg/kg bw/day	rat	oral	34 day	Short Term Toxicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	2000	mg/kg bw/day	rat	oral	28 day	Short Term Toxicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	410.5	mg/kg bw/day	mouse	oral	35 day	Short Term Toxicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	500	mg/kg bw/day	rat	oral	10 day	Short Term Toxicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	100	mg/kg bw/day	rat	oral	10 day	Short Term Toxicity	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB	NOAEL	25	mg/kg bw/day	rat	oral	3 day	Special Toxicology Study	US FDA CFSAN PAFA; US FDA CFSAN PAFA Study

ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip 42 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	250	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=e1be6ead-8c4b-4029-bc5e-bf8ca86ccc8f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	1000	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=3a114673-6cbf-4378-8dac-592d6632cd7b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	<=70	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=70; entry_uuid=2bc4e12c-647d-4c27-88c5-bdbeb93dd9f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	ca.1250	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=b2a66392-a7a7-4d33-83b1-e98eac882bbf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	625	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=7fc3d538-e5c8-4990-94ee-182b90de5d8e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	900	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=fbb8d619-e2b3-4ce8-a1fc-e45baf7342f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	250	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=e1be6ead-8c4b-4029-bc5e-bf8ca86ccc8f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	1000	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=3a114673-6cbf-4378-8dac-592d6632cd7b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	<=70	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=70; entry_uuid=2bc4e12c-647d-4c27-88c5-bdbeb93dd9f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	ca.1250	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=b2a66392-a7a7-4d33-83b1-e98eac882bbf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	625	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=7fc3d538-e5c8-4990-94ee-182b90de5d8e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	900	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=fbb8d619-e2b3-4ce8-a1fc-e45baf7342f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	250	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=e1be6ead-8c4b-4029-bc5e-bf8ca86ccc8f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	1000	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=3a114673-6cbf-4378-8dac-592d6632cd7b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	<=70	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=70; entry_uuid=2bc4e12c-647d-4c27-88c5-bdbeb93dd9f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	ca.1250	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=b2a66392-a7a7-4d33-83b1-e98eac882bbf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	625	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=7fc3d538-e5c8-4990-94ee-182b90de5d8e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	LOAEL	900	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=fbb8d619-e2b3-4ce8-a1fc-e45baf7342f0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	500	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=86a0e12a-aac7-4188-bae5-d44adaa7d687
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=700	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; entry_uuid=7facc41b-b06b-4e51-8369-a48bfa03b95a
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=230	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=700; entry_uuid=5e067afb-c47f-4a90-8397-eccdc500c14b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	ca.600	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=ce9ee45c-275f-4d74-9455-ca1e600fee45
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	100	mg/kg bw/day	mouse	oral: unspecified	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=843372a7-c20d-4485-86e0-c1dd108a9490_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=843372a7-c20d-4485-86e0-c1dd108a9490/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2003; basis=other:; key_result=false; entry_uuid=21ad174a-d860-4d4a-b357-a9789ca68d33
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	300	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=af1e82cb-2cb1-4be9-a933-75af0ff9a3c3
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=900	mg/kg bw/day	mouse	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=56adb2e6-25a4-4c11-9885-23d2fbe0ea79_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=56adb2e6-25a4-4c11-9885-23d2fbe0ea79/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=d25413c3-ab37-40f3-a5c4-19c75627b43e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	450	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=8a3cab09-bf66-48e2-977a-d2e84ddb348f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	500	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=86a0e12a-aac7-4188-bae5-d44adaa7d687
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=700	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; entry_uuid=7facc41b-b06b-4e51-8369-a48bfa03b95a
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=230	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=700; entry_uuid=5e067afb-c47f-4a90-8397-eccdc500c14b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	ca.600	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=ce9ee45c-275f-4d74-9455-ca1e600fee45
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	100	mg/kg bw/day	mouse	oral: unspecified	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=843372a7-c20d-4485-86e0-c1dd108a9490_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=843372a7-c20d-4485-86e0-c1dd108a9490/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2003; basis=other:; key_result=false; entry_uuid=21ad174a-d860-4d4a-b357-a9789ca68d33
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	300	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=af1e82cb-2cb1-4be9-a933-75af0ff9a3c3
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=900	mg/kg bw/day	mouse	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=56adb2e6-25a4-4c11-9885-23d2fbe0ea79_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=56adb2e6-25a4-4c11-9885-23d2fbe0ea79/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=d25413c3-ab37-40f3-a5c4-19c75627b43e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	450	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=8a3cab09-bf66-48e2-977a-d2e84ddb348f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	500	mg/kg bw/day	rat	oral: gavage	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=c3320cd7-8ec1-4b49-be6d-7e8346f2dba3/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=1999; basis=other:; key_result=false; entry_uuid=86a0e12a-aac7-4188-bae5-d44adaa7d687
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=700	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; entry_uuid=7facc41b-b06b-4e51-8369-a48bfa03b95a
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=230	mg/kg bw/day	rat	oral: gavage	-	two-generation reproductive toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=7f2b1a9e-4f61-4397-9cb0-f20ae36dede2/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2003; ReportDate=2003-08-22; basis=other:; key_result=false; upper_value=700; entry_uuid=5e067afb-c47f-4a90-8397-eccdc500c14b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	ca.600	mg/kg bw/day	rat	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=759d7b1a-6167-4ad5-ae73-bf57b1c3e856_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=759d7b1a-6167-4ad5-ae73-bf57b1c3e856/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=ce9ee45c-275f-4d74-9455-ca1e600fee45
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	100	mg/kg bw/day	mouse	oral: unspecified	-	developmental toxicity	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=843372a7-c20d-4485-86e0-c1dd108a9490_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=843372a7-c20d-4485-86e0-c1dd108a9490/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2003; basis=other:; key_result=false; entry_uuid=21ad174a-d860-4d4a-b357-a9789ca68d33
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	300	mg/kg bw/day	rat	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=a64fd3d9-f1d3-4517-ac36-49aa678f6e37_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=a64fd3d9-f1d3-4517-ac36-49aa678f6e37/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=af1e82cb-2cb1-4be9-a933-75af0ff9a3c3
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	>=900	mg/kg bw/day	mouse	oral: feed	-	sub-chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=56adb2e6-25a4-4c11-9885-23d2fbe0ea79_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=56adb2e6-25a4-4c11-9885-23d2fbe0ea79/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=d25413c3-ab37-40f3-a5c4-19c75627b43e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip	NOAEL	450	mg/kg bw/day	mouse	oral: feed	-	chronic toxicity: oral	dossier=4d11bf83-5cec-489b-9e4e-e2efec390d66.i6z; document=d7f5a1d4-6375-4b56-a19f-823f7cad02e6_4d11bf83-5cec-489b-9e4e-e2efec390d66.i6d; document_key=d7f5a1d4-6375-4b56-a19f-823f7cad02e6/4d11bf83-5cec-489b-9e4e-e2efec390d66; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1983; ReportDate=1983-12-30; basis=other:; key_result=false; entry_uuid=8a3cab09-bf66-48e2-977a-d2e84ddb348f

EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx 3 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx	NOAEL	=100	mg/kg bw/day	Rabbit	-	-	reproduction toxicity	EFSA - 2012 - OutputID 1313 - clinical signs - systemic - Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil - doi:10.2903/j.efsa.2012.2506
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx	NOAEL	=300	mg/kg bw/day	Rat	-	730 days	chronic/long term toxicity	EFSA AFC - 2009 - OutputID 2311 - body weight - systemic - Flavouring Group Evaluation 60 (FGE.60): Consideration of eugenol and related hydroxyallylbenzene derivatives evaluated by JECFA (65th meeting) structurally related to ring-substituted phenolic substances evaluated by EFSA in FGE.22 (2006). Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) - doi:10.2903/j.efsa.2009.965
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx	NOEL	=250	mg/kg bw	Rat	-	-	reproduction toxicity	EFSA - 2012 - OutputID 1345 - development - developmental - Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol - doi:10.2903/j.efsa.2012.2914

EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx 4 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx	ADI	=1	mg/kg bw/day	Consumers	-	-	ADI	EFSA - 2012 - OutputID 1313 - Consumers - Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil - doi:10.2903/j.efsa.2012.2506
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx	ADI	=2.5	mg/kg bw/day	Consumers	-	-	ADI	EFSA FEEDAP - 2011 - OutputID 145 - Consumers - Scientific Opinion on the safety and efficacy of allylhydroxybenzenes (chemical group 18) when used as flavourings for all animal species - doi:10.2903/j.efsa.2011.2440
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx	ADI	=1	mg/kg bw/day	Consumers	-	-	ADI	EFSA - 2012 - OutputID 1313 - Consumers - Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil - doi:10.2903/j.efsa.2012.2506
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx	ADI	=2.5	mg/kg bw/day	Consumers	-	-	ADI	EFSA FEEDAP - 2011 - OutputID 145 - Consumers - Scientific Opinion on the safety and efficacy of allylhydroxybenzenes (chemical group 18) when used as flavourings for all animal species - doi:10.2903/j.efsa.2011.2440

IARC Monographs 1 endpoint

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
IARC Monographs	IARC carcinogenicity classification	3	IARC group	-	-	1987	IARC Monographs	{"additional_info":"volume_publication_year=1987","evaluation_year":1987,"source_table":"iarc_classifications","volume":"36, Sup 7"}

INCHEM_WHO_jecfa_jecmono_v14je11 2 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
INCHEM_WHO_jecfa_jecmono_v14je11	ADI	range:0-55	mg/kg bw/day	-	oral	-	Health guidance value	document_id=jecfa_jecmono_v14je11; title=475. Eugenol (WHO Food Additives Series 14); path=mirror/documents/jecfa/jecmono/v14je11.htm; row_hash=0e7005165c90fd09; raw_unit=mg/kg bw; context=Series 14) EUGENOL Explanation Eugenol was reviewed at the eleventh meeting of the FAO/WHO Joint Expert Committee on Food Additives, specifications were prepared and a conditional ADI of 0-5 mg/kg bw was established (Anon.
INCHEM_WHO_jecfa_jecmono_v14je11	ADI	range:0-2.52.5	mg/kg bw/day	-	oral	-	Health guidance value	document_id=jecfa_jecmono_v14je11; title=475. Eugenol (WHO Food Additives Series 14); path=mirror/documents/jecfa/jecmono/v14je11.htm; row_hash=ef016caf9dc4c1cd; raw_unit=mg/kg bw; context=1% in the diet equivalent to 500 mg/kg bw Estimate of temporary acceptable daily intake for man 0-2.5 mg/kg bw FURTHER WORK OR INFORMATION Required by 1982 Completion of ongoing carcinogenic studies.

INCHEM_WHO_jecfa_jecmono_v17je10 1 endpoint

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
INCHEM_WHO_jecfa_jecmono_v17je10	ADI	range:0-2.52.5	mg/kg bw/day	-	-	-	Health guidance value	document_id=jecfa_jecmono_v17je10; title=530. Eugenol (WHO Food Additives Series 17); path=mirror/documents/jecfa/jecmono/v17je10.htm; row_hash=d2073ba839f6e518; raw_unit=mg/kg bw; context=Estimates of acceptable daily intake for man 0-2.5 mg/kg bw REFERENCES Anon. (1978) Scientific Literature Review of Eugenol and Related Substances in Flavor Usage Caujolle, F. & Meynier, D. (1960a) Hypothermic activity in the eugenol and safrole series, Ann.

NTP_ICE_acute_oral 2 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_acute_oral	LD50	=1930	mg/kg bw	Rat	oral	acute	Rat Acute Oral Toxicity	NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_11846; row=15325; data_type=In Vivo; mixture=Chemical; chemical_name=Eugenol; preferred_name=Eugenol; dtxsid=DTXSID9020617; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9020617; source_file=acute_oral.xlsx
NTP_ICE_acute_oral	LD50	>2000	mg/kg bw	Rat	oral	acute	Rat Acute Oral Toxicity	record_id=acute_oral_11847; row=15326; data_type=In Vivo; mixture=Chemical; chemical_name=Eugenol; preferred_name=Eugenol; dtxsid=DTXSID9020617; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9020617; source_file=acute_oral.xlsx

NTP_ICE_adme_parameters 2 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_adme_parameters	Clint	103.6	uL/min/10^6 cells	Human	-	-	Measured; httk, Human Hepatic Intrinsic Clearance	sheet=Data; excel_row=3522; Record_ID=adme_parameters_391; Data_Type=Measured; DTXSID=DTXSID9020617; Assay=httk, Human Hepatic Intrinsic Clearance; Endpoint=Clint; Response=103.6; Response_Unit=ul/min/10^6 cells; Species=Human; Reference=httk2.3.1, Wetmore 2015; URL=https://cran.r-project.org/web/packages/httk/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_adme_parameters	Fu	0.1922	fraction	Human	-	-	Measured; httk, Human Plasma Fraction Unbound	sheet=Data; excel_row=3521; Record_ID=adme_parameters_391; Data_Type=Measured; DTXSID=DTXSID9020617; Assay=httk, Human Plasma Fraction Unbound; Endpoint=Fu; Response=0.1922; Response_Unit=Unitless Fraction; Species=Human; Reference=httk2.3.1, Wetmore 2015; URL=https://cran.r-project.org/web/packages/httk/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617

NTP_ICE_cancer 3 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_cancer	IARC group	3	unitless	-	-	-	WOE; IARC Carcinogenicity	sheet=Data; excel_row=9729; Record_ID=cancer_5285; Data_Type=WOE; Formulation_Name=Eugenol; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=IARC Carcinogenicity; Endpoint=IARC group; Response=3; Response_Unit=Unitless; URL=http://publications.iarc.fr/54; http://publications.iarc.fr/139; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_cancer	Top dose	6000	ppm	Mouse	Dosed feed	-	In Vivo; NTP Carcinogenicity	sheet=Data; excel_row=9725; Record_ID=cancer_5283; Data_Type=In Vivo; Formulation_Name=Eugenol; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=6000; Response_Unit=ppm; Species=Mouse; Strain=B6C3F1; Sex=Male; Route=Dosed feed; Reference=TR-223; URL=https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr223/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_cancer	Top dose	12500	ppm	Rat	Dosed feed	-	In Vivo; NTP Carcinogenicity	sheet=Data; excel_row=9732; Record_ID=cancer_5288; Data_Type=In Vivo; Formulation_Name=Eugenol; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=12500; Response_Unit=ppm; Species=Rat; Strain=F344/N; Sex=Female; Route=Dosed feed; Reference=TR-223; URL=https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr223/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617

NTP_ICE_endocrine 1 endpoint

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_endocrine	Model Score	0	unitless	-	-	-	ARPathway2016; AR Pathway Model, Antagonist	sheet=Integrated_approaches; excel_row=9232; RecordID=ARPathway2016_1788; DatasetName=ARPathway2016; DTXSID=DTXSID9020617; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617

NTP_ICE_skin_irritation 60 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_skin_irritation	Positive reaction	15.3	%	Human	Dermal	-	In Vivo; Four-hour Human Patch Test	sheet=Data_invivo; excel_row=1847; Record_ID=skin_irritation_invivo_10; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=15.3; Response_Unit=%; Species=Human; Reference=Basketter et al. 2004; 15291823; 10.1111/j.0105-1873.2004.00385.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability	12.1	%	-	Dermal	-	In Vitro; EpiDerm Irritation	sheet=Data_invitro; excel_row=5756; Record_ID=skin_irritation_invitro_1347; Data_Type=In Vitro; Formulation_Name=Eugenol; Concentration=99; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Irritation; Endpoint=Viability; Response=12.1; Response_Unit=%; Reference=Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability	10.8	%	-	Dermal	-	In Vitro; EpiDerm Irritation	sheet=Data_invitro; excel_row=5757; Record_ID=skin_irritation_invitro_1346; Data_Type=In Vitro; Formulation_Name=Eugenol; Concentration=99; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Irritation; Endpoint=Viability; Response=10.8; Response_Unit=%; Reference=Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability	9.57	%	-	Dermal	-	In Vitro; EpiSkin Irritation	sheet=Data_invitro; excel_row=5758; Record_ID=skin_irritation_invitro_1345; Data_Type=In Vitro; Formulation_Name=Eugenol; Concentration=99; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Irritation; Endpoint=Viability; Response=9.57; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability	5.44	%	-	Dermal	-	In Vitro; EpiSkin Irritation	sheet=Data_invitro; excel_row=5759; Record_ID=skin_irritation_invitro_1344; Data_Type=In Vitro; Formulation_Name=Eugenol; Concentration=99; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Irritation; Endpoint=Viability; Response=5.44; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability	12.6	%	-	Dermal	-	In Vitro; EpiDerm Irritation	sheet=Data_invitro; excel_row=5768; Record_ID=skin_irritation_invitro_1348; Data_Type=In Vitro; Formulation_Name=Eugenol; Concentration=99; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Irritation; Endpoint=Viability; Response=12.6; Response_Unit=%; Reference=Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (18 hours)	30.1	%	-	Dermal	-	In Vitro; Vitrolife-Skin Irritation	sheet=Data_invitro; excel_row=5782; Record_ID=skin_irritation_invitro_213; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (18 hours); Response=30.1; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (240 minutes)	14.2	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5730; Record_ID=skin_irritation_invitro_2005; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=14.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (240 minutes)	12.1	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5731; Record_ID=skin_irritation_invitro_2003; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=12.1; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (240 minutes)	42.7	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5732; Record_ID=skin_irritation_invitro_2001; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=42.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	82.3	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5695; Record_ID=skin_irritation_invitro_2011; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=82.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	111.3	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5696; Record_ID=skin_irritation_invitro_2009; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=111.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	100.1	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5697; Record_ID=skin_irritation_invitro_2007; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=100.1; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	132.9	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5698; Record_ID=skin_irritation_invitro_2005; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=132.9; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	121.7	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5699; Record_ID=skin_irritation_invitro_2003; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=121.7; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	188.4	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5700; Record_ID=skin_irritation_invitro_2001; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=188.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	77.4	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5701; Record_ID=skin_irritation_invitro_1999; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=77.40; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	91.4	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5702; Record_ID=skin_irritation_invitro_1997; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=91.4; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	87.7	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5703; Record_ID=skin_irritation_invitro_1995; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=87.7; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	92.3	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5704; Record_ID=skin_irritation_invitro_1993; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=92.3; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	59.4	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5705; Record_ID=skin_irritation_invitro_1991; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=59.4; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	85.5	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5706; Record_ID=skin_irritation_invitro_1988; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=85.5; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	61.9	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5707; Record_ID=skin_irritation_invitro_1986; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=61.9; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	88.2	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5708; Record_ID=skin_irritation_invitro_1984; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=88.2; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	60.1	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5709; Record_ID=skin_irritation_invitro_1982; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=60.1; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	64.8	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5710; Record_ID=skin_irritation_invitro_1980; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=64.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	107.5	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5711; Record_ID=skin_irritation_invitro_1978; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=107.5; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	107.2	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5712; Record_ID=skin_irritation_invitro_1976; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=107.2; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	79.8	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5714; Record_ID=skin_irritation_invitro_1972; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=79.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	83.8	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5715; Record_ID=skin_irritation_invitro_1971; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=83.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	113.8	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5716; Record_ID=skin_irritation_invitro_1969; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=113.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	100.7	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5717; Record_ID=skin_irritation_invitro_2017; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=100.7; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	77.9	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5718; Record_ID=skin_irritation_invitro_2015; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=77.90; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (3 minutes)	101.8	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5719; Record_ID=skin_irritation_invitro_2013; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=101.8; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (42 hours)	26.3	%	-	Dermal	-	In Vitro; Vitrolife-Skin Irritation	sheet=Data_invitro; excel_row=5761; Record_ID=skin_irritation_invitro_213; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (42 hours); Response=26.3; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	24.2	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5692; Record_ID=skin_irritation_invitro_1972; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=24.2; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	30.5	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5693; Record_ID=skin_irritation_invitro_1971; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=30.5; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	32.6	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5694; Record_ID=skin_irritation_invitro_1969; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=32.6; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	66.4	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5748; Record_ID=skin_irritation_invitro_2017; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=66.40; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	61.4	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5750; Record_ID=skin_irritation_invitro_2015; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=61.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	36.2	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5755; Record_ID=skin_irritation_invitro_1980; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=36.20; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	47.8	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5762; Record_ID=skin_irritation_invitro_2013; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=47.8; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	56.2	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5763; Record_ID=skin_irritation_invitro_2011; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=56.2; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	69.9	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5764; Record_ID=skin_irritation_invitro_2009; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=69.90; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	122.4	%	-	Dermal	-	In Vitro; EpiDerm Corrosion	sheet=Data_invitro; excel_row=5765; Record_ID=skin_irritation_invitro_2007; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=122.4; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	74.8	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5766; Record_ID=skin_irritation_invitro_2005; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=74.8; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	86	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5767; Record_ID=skin_irritation_invitro_2003; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=86; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	72.2	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5769; Record_ID=skin_irritation_invitro_1999; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=72.2; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	80.3	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5770; Record_ID=skin_irritation_invitro_1997; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=80.3; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	62	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5771; Record_ID=skin_irritation_invitro_1995; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=62; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	81.7	%	-	Dermal	-	In Vitro; LabCyte Corrosion	sheet=Data_invitro; excel_row=5772; Record_ID=skin_irritation_invitro_1993; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=81.7; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	20.5	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5773; Record_ID=skin_irritation_invitro_1991; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=20.5; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	15.3	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5774; Record_ID=skin_irritation_invitro_1988; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=15.3; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	17.2	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5775; Record_ID=skin_irritation_invitro_1986; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=17.2; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	37.4	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5776; Record_ID=skin_irritation_invitro_1984; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=37.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	43.8	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5777; Record_ID=skin_irritation_invitro_1982; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=43.8; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	24.1	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5778; Record_ID=skin_irritation_invitro_1978; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=24.1; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	28.4	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5779; Record_ID=skin_irritation_invitro_1976; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=28.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	32.4	%	-	Dermal	-	In Vitro; SkinEthic Corrosion	sheet=Data_invitro; excel_row=5780; Record_ID=skin_irritation_invitro_1974; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=32.4; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_irritation	Viability (60 minutes)	122.3	%	-	Dermal	-	In Vitro; EpiSkin Corrosion	sheet=Data_invitro; excel_row=5781; Record_ID=skin_irritation_invitro_2001; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=122.3; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617

NTP_ICE_skin_sensitization 166 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
NTP_ICE_skin_sensitization	CD54, EC200	137.2	ug/mL	-	Dermal	-	In Vitro; CE_hCLAT2018; h-CLAT	sheet=Data_invitro; excel_row=2100; Record_ID=skin_sensitization_invitro_522; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=137.19999999999999; Reported_Response_Unit=ug/mL; Response=137.2; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	90	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2604; Record_ID=skin_sensitization_invitro_621; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=90; Reported_Response_Unit=ug/mL; Response=90; Response_Unit=ug/mL; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	108.8	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2608; Record_ID=skin_sensitization_invitro_623; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=108.8; Reported_Response_Unit=ug/mL; Response=108.8; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	72.3	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2615; Record_ID=skin_sensitization_invitro_624; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=72.3; Reported_Response_Unit=ug/mL; Response=72.3; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	117.7	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2630; Record_ID=skin_sensitization_invitro_626; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=117.7; Reported_Response_Unit=ug/mL; Response=117.7; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	53.4	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2639; Record_ID=skin_sensitization_invitro_628; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=53.4; Reported_Response_Unit=ug/mL; Response=53.4; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	265.2	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2651; Record_ID=skin_sensitization_invitro_629; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=265.2; Reported_Response_Unit=ug/mL; Response=265.2; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	112.2	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2655; Record_ID=skin_sensitization_invitro_630; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=112.2; Reported_Response_Unit=ug/mL; Response=112.2; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	125.2	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2662; Record_ID=skin_sensitization_invitro_632; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=125.2; Reported_Response_Unit=ug/mL; Response=125.2; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD54, EC200	169.4	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2676; Record_ID=skin_sensitization_invitro_634; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=169.4; Reported_Response_Unit=ug/mL; Response=169.4; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC120	5.698	ug/mL	-	Dermal	-	In Vitro; Urbisch_SkinSensitization2020; mMUSST	sheet=Data_invitro; excel_row=7785; Record_ID=skin_sensitization_invitro_1883; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=mMUSST; Endpoint=CD86, EC120; Reported_Response=34.7; Reported_Response_Unit=uM; Conversion_Factor_Value=164.204; Conversion_Factor_Source=EPA Dashboard; Converted_Response=5.698; Converted_Response_Unit=ug/mL; Response=5.698; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	64.4	ug/mL	-	Dermal	-	In Vitro; CE_hCLAT2018; h-CLAT	sheet=Data_invitro; excel_row=2099; Record_ID=skin_sensitization_invitro_522; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=64.400000000000006; Reported_Response_Unit=ug/mL; Response=64.4; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	77	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2603; Record_ID=skin_sensitization_invitro_621; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=77; Reported_Response_Unit=ug/mL; Response=77; Response_Unit=ug/mL; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	136.3	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2609; Record_ID=skin_sensitization_invitro_623; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=136.30000000000001; Reported_Response_Unit=ug/mL; Response=136.3; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	154.9	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2619; Record_ID=skin_sensitization_invitro_624; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=154.9; Reported_Response_Unit=ug/mL; Response=154.9; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	53.1	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2627; Record_ID=skin_sensitization_invitro_626; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=53.1; Reported_Response_Unit=ug/mL; Response=53.1; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	157.5	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2643; Record_ID=skin_sensitization_invitro_628; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=157.5; Reported_Response_Unit=ug/mL; Response=157.5; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	204.8	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2649; Record_ID=skin_sensitization_invitro_629; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=204.8; Reported_Response_Unit=ug/mL; Response=204.8; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	163.8	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2674; Record_ID=skin_sensitization_invitro_634; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=163.80000000000001; Reported_Response_Unit=ug/mL; Response=163.8; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	25.001	ug/mL	-	Dermal	-	In Vitro; Urbisch_SkinSensitization2020; U-SENS	sheet=Data_invitro; excel_row=8226; Record_ID=skin_sensitization_invitro_2249; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=152.2533496; Reported_Response_Unit=uM; Conversion_Factor_Value=164.204; Conversion_Factor_Source=EPA Dashboard; Converted_Response=25.001; Converted_Response_Unit=ug/mL; Response=25.001; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CD86, EC150	29.36	ug/mL	-	Dermal	-	In Vitro; CE_USENSE2018; U-SENS	sheet=Data_invitro; excel_row=8590; Record_ID=skin_sensitization_invitro_2373; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=29.36; Reported_Response_Unit=ug/mL; Response=29.36; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV70	141.6	ug/mL	-	Dermal	-	In Vitro; CE_USENSE2018; U-SENS	sheet=Data_invitro; excel_row=8589; Record_ID=skin_sensitization_invitro_2373; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=U-SENS; Endpoint=CV70; Reported_Response=141.58; Reported_Response_Unit=ug/mL; Response=141.6; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	143.2	ug/mL	-	Dermal	-	In Vitro; CE_hCLAT2018; h-CLAT	sheet=Data_invitro; excel_row=2101; Record_ID=skin_sensitization_invitro_522; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=143.19999999999999; Reported_Response_Unit=ug/mL; Response=143.2; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	95.8	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2605; Record_ID=skin_sensitization_invitro_621; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=95.8; Reported_Response_Unit=ug/mL; Response=95.8; Response_Unit=ug/mL; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	150	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2610; Record_ID=skin_sensitization_invitro_623; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=150; Reported_Response_Unit=ug/mL; Response=150; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	234	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2650; Record_ID=skin_sensitization_invitro_629; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=234; Reported_Response_Unit=ug/mL; Response=234; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	320	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2660; Record_ID=skin_sensitization_invitro_630; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=320; Reported_Response_Unit=ug/mL; Response=320; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	140.2	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2663; Record_ID=skin_sensitization_invitro_632; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=140.19999999999899; Reported_Response_Unit=ug/mL; Response=140.2; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	CV75	147	ug/mL	-	Dermal	-	In Vitro; hCLAT2015; h-CLAT	sheet=Data_invitro; excel_row=2671; Record_ID=skin_sensitization_invitro_634; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=h-CLAT; Endpoint=CV75; Reported_Response=147; Reported_Response_Unit=ug/mL; Response=147; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Concentration, 5% incidence of positive responses	14.6	%	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11443; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Concentration, 5% incidence of positive responses; Response=14.6; Response_Unit=%; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Concentration, one positive response	4	%	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11439; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Concentration, one positive response; Response=4; Response_Unit=%; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Cys	38.3	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=482; Record_ID=skin_sensitization_invitro_144; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=38.299999999999997; Reported_Response_Unit=%; Response=38.3; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Cys	32.1	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=494; Record_ID=skin_sensitization_invitro_147; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=32.1; Reported_Response_Unit=%; Response=32.1; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Cys	9.2	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=505; Record_ID=skin_sensitization_invitro_150; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=9.1999999999999993; Reported_Response_Unit=%; Response=9.2; Response_Unit=%; Reference=Jaworska supp A 2013; 21993957; 10.14573/altex.2011.3.211|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys	4.2	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=481; Record_ID=skin_sensitization_invitro_144; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=4.2; Reported_Response_Unit=%; Response=4.2; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys	10.2	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=492; Record_ID=skin_sensitization_invitro_147; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=10.199999999999999; Reported_Response_Unit=%; Response=10.2; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys	19.2	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=503; Record_ID=skin_sensitization_invitro_150; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=19.2; Reported_Response_Unit=%; Response=19.2; Response_Unit=%; Reference=Jaworska supp A 2013; 21993957; 10.14573/altex.2011.3.211|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys + Cys	21.25	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=484; Record_ID=skin_sensitization_invitro_144; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=21.25; Reported_Response_Unit=%; Response=21.25; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys + Cys	21	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=497; Record_ID=skin_sensitization_invitro_147; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=21; Reported_Response_Unit=%; Response=21; Response_Unit=%; Reference=Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006|Nukada personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Depletion Lys + Cys	14.2	%	-	Dermal	-	In Vitro; DPRA2015; DPRA	sheet=Data_invitro; excel_row=509; Record_ID=skin_sensitization_invitro_150; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=14.2; Reported_Response_Unit=%; Response=14.2; Response_Unit=%; Reference=Jaworska supp A 2013; 21993957; 10.14573/altex.2011.3.211|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	197.48	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7187; Record_ID=skin_sensitization_invitro_1709; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=197.48; Reported_Response_Unit=uM; Response=197.48; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	>2000	uM	-	Dermal	-	In Vitro; CE_KeratinoSense2018; KeratinoSens	sheet=Data_invitro; excel_row=7188; Record_ID=skin_sensitization_invitro_1711; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2000; Reported_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	229.61	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7189; Record_ID=skin_sensitization_invitro_1724; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=229.61; Reported_Response_Unit=uM; Response=229.61; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	231.2	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7190; Record_ID=skin_sensitization_invitro_1704; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=231.2; Reported_Response_Unit=uM; Response=231.2; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	235.99	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7191; Record_ID=skin_sensitization_invitro_1708; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=235.99; Reported_Response_Unit=uM; Response=235.99; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	237.15	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7192; Record_ID=skin_sensitization_invitro_1728; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=237.15; Reported_Response_Unit=uM; Response=237.15; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	265.2	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7193; Record_ID=skin_sensitization_invitro_1710; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=265.20999999999998; Reported_Response_Unit=uM; Response=265.2; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	268.1	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7194; Record_ID=skin_sensitization_invitro_1705; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=268.08999999999997; Reported_Response_Unit=uM; Response=268.1; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	309.1	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7195; Record_ID=skin_sensitization_invitro_1703; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=309.10000000000002; Reported_Response_Unit=uM; Response=309.1; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	322.52	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7196; Record_ID=skin_sensitization_invitro_1707; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=322.52; Reported_Response_Unit=uM; Response=322.52; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	341.49	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7197; Record_ID=skin_sensitization_invitro_1706; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=341.49; Reported_Response_Unit=uM; Response=341.49; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	505.5	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7198; Record_ID=skin_sensitization_invitro_1720; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=505.5; Reported_Response_Unit=uM; Response=505.5; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	64	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7199; Record_ID=skin_sensitization_invitro_1702; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=64; Reported_Response_Unit=uM; Response=64; Response_Unit=uM; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC1.5	<241.13	uM	-	Dermal	-	In Vitro; Urbisch_SkinSensitization2020; LuSens	sheet=Data_invitro; excel_row=7589; Record_ID=skin_sensitization_invitro_1830; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LuSens; Endpoint=EC1.5; Response_Modifier=<; Reported_Response_Modifier=<; Reported_Response=241.13; Reported_Response_Unit=uM; Response=241.13; Response_Unit=uM; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	10.1	%	Mouse	Dermal	-	In Vivo; LLNA2013; LLNA	sheet=Data_invivo; excel_row=12889; Record_ID=skin_sensitization_invivo_497; Data_Type=In Vivo; Internal_Data_Source=LLNA2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=10.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	14.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13212; Record_ID=skin_sensitization_invivo_3276; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=14.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13216; Record_ID=skin_sensitization_invivo_3281; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	13.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13219; Record_ID=skin_sensitization_invivo_3284; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=13.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13222; Record_ID=skin_sensitization_invivo_3290; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Lalko and Api 2006; 16324777; 10.1016/j.fct.2005.10.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.2	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13223; Record_ID=skin_sensitization_invivo_3291; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.2; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 1992; 1459374; 10.1016/0272-0590(92)90183-i; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13224; Record_ID=skin_sensitization_invivo_3293; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	9.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13225; Record_ID=skin_sensitization_invivo_3294; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=9.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	20.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13226; Record_ID=skin_sensitization_invivo_3295; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=20.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	6	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13227; Record_ID=skin_sensitization_invivo_3296; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.1	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13228; Record_ID=skin_sensitization_invivo_3297; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	12.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13229; Record_ID=skin_sensitization_invivo_3298; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=12.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Bertrand et al. 1997; 9084914; 10.1021/tx960087v; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	40.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13230; Record_ID=skin_sensitization_invivo_3299; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=40.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber and Weisenberger 1991; 2061551; 10.1002/jat.2550110211; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13233; Record_ID=skin_sensitization_invivo_3302; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	14.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13212; Record_ID=skin_sensitization_invivo_3276; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=14.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13216; Record_ID=skin_sensitization_invivo_3281; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	13.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13219; Record_ID=skin_sensitization_invivo_3284; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=13.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13222; Record_ID=skin_sensitization_invivo_3290; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Lalko and Api 2006; 16324777; 10.1016/j.fct.2005.10.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.2	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13223; Record_ID=skin_sensitization_invivo_3291; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.2; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 1992; 1459374; 10.1016/0272-0590(92)90183-i; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13224; Record_ID=skin_sensitization_invivo_3293; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	9.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13225; Record_ID=skin_sensitization_invivo_3294; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=9.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	20.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13226; Record_ID=skin_sensitization_invivo_3295; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=20.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	6	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13227; Record_ID=skin_sensitization_invivo_3296; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.1	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13228; Record_ID=skin_sensitization_invivo_3297; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	12.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13229; Record_ID=skin_sensitization_invivo_3298; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=12.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Bertrand et al. 1997; 9084914; 10.1021/tx960087v; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	40.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13230; Record_ID=skin_sensitization_invivo_3299; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=40.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber and Weisenberger 1991; 2061551; 10.1002/jat.2550110211; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13233; Record_ID=skin_sensitization_invivo_3302; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	14.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13212; Record_ID=skin_sensitization_invivo_3276; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=14.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13216; Record_ID=skin_sensitization_invivo_3281; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	13.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13219; Record_ID=skin_sensitization_invivo_3284; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=13.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13222; Record_ID=skin_sensitization_invivo_3290; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Lalko and Api 2006; 16324777; 10.1016/j.fct.2005.10.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.2	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13223; Record_ID=skin_sensitization_invivo_3291; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.2; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 1992; 1459374; 10.1016/0272-0590(92)90183-i; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13224; Record_ID=skin_sensitization_invivo_3293; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	9.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13225; Record_ID=skin_sensitization_invivo_3294; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=9.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	20.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13226; Record_ID=skin_sensitization_invivo_3295; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=20.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	6	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13227; Record_ID=skin_sensitization_invivo_3296; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.1	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13228; Record_ID=skin_sensitization_invivo_3297; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	12.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13229; Record_ID=skin_sensitization_invivo_3298; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=12.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Bertrand et al. 1997; 9084914; 10.1021/tx960087v; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	40.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13230; Record_ID=skin_sensitization_invivo_3299; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=40.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber and Weisenberger 1991; 2061551; 10.1002/jat.2550110211; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13233; Record_ID=skin_sensitization_invivo_3302; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	14.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13212; Record_ID=skin_sensitization_invivo_3276; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=14.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13216; Record_ID=skin_sensitization_invivo_3281; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	13.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13219; Record_ID=skin_sensitization_invivo_3284; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=13.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13222; Record_ID=skin_sensitization_invivo_3290; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Lalko and Api 2006; 16324777; 10.1016/j.fct.2005.10.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.2	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13223; Record_ID=skin_sensitization_invivo_3291; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.2; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 1992; 1459374; 10.1016/0272-0590(92)90183-i; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	18.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13224; Record_ID=skin_sensitization_invivo_3293; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=18.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	9.5	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13225; Record_ID=skin_sensitization_invivo_3294; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=9.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	20.4	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13226; Record_ID=skin_sensitization_invivo_3295; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=20.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	6	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13227; Record_ID=skin_sensitization_invivo_3296; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	8.1	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13228; Record_ID=skin_sensitization_invivo_3297; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=8.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber et al. 1991; 1998208; 10.1016/0378-4274(91)90135-s; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	12.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13229; Record_ID=skin_sensitization_invivo_3298; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=12.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Bertrand et al. 1997; 9084914; 10.1021/tx960087v; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	40.9	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13230; Record_ID=skin_sensitization_invivo_3299; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=40.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Kimber and Weisenberger 1991; 2061551; 10.1002/jat.2550110211; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	EC3	5.8	%	Mouse	Dermal	-	In Vivo; LLNAdb2013; LLNA	sheet=Data_invivo; excel_row=13233; Record_ID=skin_sensitization_invivo_3302; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=EC3; Response=5.8; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1281	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7216; Record_ID=skin_sensitization_invitro_1713; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1281.4000000000001; Reported_Response_Unit=uM; Response=1281; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1294.71	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7217; Record_ID=skin_sensitization_invitro_1725; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1294.71; Reported_Response_Unit=uM; Response=1294.71; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1329.46	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7218; Record_ID=skin_sensitization_invitro_1721; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1329.46; Reported_Response_Unit=uM; Response=1329.46; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1333.6	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7219; Record_ID=skin_sensitization_invitro_1720; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1333.6; Reported_Response_Unit=uM; Response=1333.6; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1363.2	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7220; Record_ID=skin_sensitization_invitro_1712; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1363.2; Reported_Response_Unit=uM; Response=1363.2; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1428.75	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7221; Record_ID=skin_sensitization_invitro_1717; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1428.75; Reported_Response_Unit=uM; Response=1428.75; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1454.95	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7222; Record_ID=skin_sensitization_invitro_1709; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1454.95; Reported_Response_Unit=uM; Response=1454.95; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1486.58	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7223; Record_ID=skin_sensitization_invitro_1706; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1486.58; Reported_Response_Unit=uM; Response=1486.58; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1487.1	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7224; Record_ID=skin_sensitization_invitro_1704; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1487.1; Reported_Response_Unit=uM; Response=1487.1; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1496.6	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7225; Record_ID=skin_sensitization_invitro_1703; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1496.6; Reported_Response_Unit=uM; Response=1496.6; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1503.9	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7226; Record_ID=skin_sensitization_invitro_1702; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1503.9; Reported_Response_Unit=uM; Response=1503.9; Response_Unit=uM; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1505.69	uM	-	Dermal	-	In Vitro; CE_KeratinoSense2018; KeratinoSens	sheet=Data_invitro; excel_row=7227; Record_ID=skin_sensitization_invitro_1711; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1505.69; Reported_Response_Unit=uM; Response=1505.69; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1505.7	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7228; Record_ID=skin_sensitization_invitro_1716; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1505.7; Reported_Response_Unit=uM; Response=1505.7; Response_Unit=uM; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1506.72	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7229; Record_ID=skin_sensitization_invitro_1705; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1506.72; Reported_Response_Unit=uM; Response=1506.72; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1509.57	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7230; Record_ID=skin_sensitization_invitro_1726; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1509.57; Reported_Response_Unit=uM; Response=1509.57; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1511.74	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7231; Record_ID=skin_sensitization_invitro_1727; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1511.74; Reported_Response_Unit=uM; Response=1511.74; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1519.99	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7232; Record_ID=skin_sensitization_invitro_1708; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1519.99; Reported_Response_Unit=uM; Response=1519.99; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1538	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7233; Record_ID=skin_sensitization_invitro_1714; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1538; Reported_Response_Unit=uM; Response=1538; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1594.15	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7234; Record_ID=skin_sensitization_invitro_1728; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1594.15; Reported_Response_Unit=uM; Response=1594.15; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	1690.36	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7235; Record_ID=skin_sensitization_invitro_1724; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=1690.36; Reported_Response_Unit=uM; Response=1690.36; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	961.32	uM	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7238; Record_ID=skin_sensitization_invitro_1723; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=961.32; Reported_Response_Unit=uM; Response=961.32; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	IC50	>600	uM	-	Dermal	-	In Vitro; Urbisch_SkinSensitization2020; LuSens	sheet=Data_invitro; excel_row=7661; Record_ID=skin_sensitization_invitro_1830; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LuSens; Endpoint=IC50; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=600; Reported_Response_Unit=uM; Response=600; Response_Unit=uM; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.077	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7239; Record_ID=skin_sensitization_invitro_1721; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.077; Reported_Response_Unit=Unitless; Response=1.077; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.141	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7241; Record_ID=skin_sensitization_invitro_1726; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.141; Reported_Response_Unit=Unitless; Response=1.141; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.177	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7242; Record_ID=skin_sensitization_invitro_1723; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.177; Reported_Response_Unit=Unitless; Response=1.177; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.192	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7243; Record_ID=skin_sensitization_invitro_1722; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.1919999999999999; Reported_Response_Unit=Unitless; Response=1.192; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.215	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7244; Record_ID=skin_sensitization_invitro_1715; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.2150000000000001; Reported_Response_Unit=Unitless; Response=1.215; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.248	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7245; Record_ID=skin_sensitization_invitro_1727; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.248; Reported_Response_Unit=Unitless; Response=1.248; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.25	ratio	-	Dermal	-	In Vitro; CE_KeratinoSense2018; KeratinoSens	sheet=Data_invitro; excel_row=7246; Record_ID=skin_sensitization_invitro_1711; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.25; Reported_Response_Unit=Unitless; Response=1.25; Response_Unit=Ratio; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.264	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7247; Record_ID=skin_sensitization_invitro_1718; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.264; Reported_Response_Unit=Unitless; Response=1.264; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.3	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7249; Record_ID=skin_sensitization_invitro_1716; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.3; Reported_Response_Unit=Unitless; Response=1.3; Response_Unit=Ratio; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.329	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7250; Record_ID=skin_sensitization_invitro_1719; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.329; Reported_Response_Unit=Unitless; Response=1.329; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.384	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7252; Record_ID=skin_sensitization_invitro_1717; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.3839999999999999; Reported_Response_Unit=Unitless; Response=1.384; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.4	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7253; Record_ID=skin_sensitization_invitro_1712; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.4; Reported_Response_Unit=Unitless; Response=1.4; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.439	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7256; Record_ID=skin_sensitization_invitro_1725; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.4390000000000001; Reported_Response_Unit=Unitless; Response=1.439; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.543	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7257; Record_ID=skin_sensitization_invitro_1724; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.5429999999999999; Reported_Response_Unit=Unitless; Response=1.543; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.614	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7258; Record_ID=skin_sensitization_invitro_1720; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.6140000000000001; Reported_Response_Unit=Unitless; Response=1.614; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.7	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7259; Record_ID=skin_sensitization_invitro_1714; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.7; Reported_Response_Unit=Unitless; Response=1.7; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	1.841	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7261; Record_ID=skin_sensitization_invitro_1706; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.841; Reported_Response_Unit=Unitless; Response=1.841; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.13	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7262; Record_ID=skin_sensitization_invitro_1705; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.13; Reported_Response_Unit=Unitless; Response=2.13; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.323	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7263; Record_ID=skin_sensitization_invitro_1708; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.323; Reported_Response_Unit=Unitless; Response=2.323; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.364	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7264; Record_ID=skin_sensitization_invitro_1710; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.3639999999999999; Reported_Response_Unit=Unitless; Response=2.364; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.5	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7266; Record_ID=skin_sensitization_invitro_1703; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.5; Reported_Response_Unit=Unitless; Response=2.5; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.574	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7268; Record_ID=skin_sensitization_invitro_1728; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.5739999999999998; Reported_Response_Unit=Unitless; Response=2.574; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	2.904	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7269; Record_ID=skin_sensitization_invitro_1709; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.9039999999999999; Reported_Response_Unit=Unitless; Response=2.904; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	3.53	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7270; Record_ID=skin_sensitization_invitro_1707; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=3.53; Reported_Response_Unit=Unitless; Response=3.53; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	6.15	ratio	-	Dermal	-	In Vitro; KeratinoSens2015; KeratinoSens	sheet=Data_invitro; excel_row=7272; Record_ID=skin_sensitization_invitro_1702; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=6.15; Reported_Response_Unit=Unitless; Response=6.15; Response_Unit=Ratio; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Imax	5.494	ratio	-	Dermal	-	In Vitro; Urbisch_SkinSensitization2020; LuSens	sheet=Data_invitro; excel_row=7564; Record_ID=skin_sensitization_invitro_1830; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LuSens; Endpoint=Imax; Reported_Response=5.493771761; Reported_Response_Unit=Unitless; Response=5.494; Response_Unit=Ratio; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Incidence of positive responses	0	%	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11426; Record_ID=skin_sensitization_invivo_2484; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Akkan et al. 2003; Not available; Not available|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Incidence of positive responses	2.74	%	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11435; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Incidence of positive responses; Response=2.74; Response_Unit=%; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area	5669	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11424; Record_ID=skin_sensitization_invivo_2484; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area; Response=5669; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Akkan et al. 2003; Not available; Not available|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area	5039	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11432; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area; Response=5039; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area	4966	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Maximization Test	sheet=Data_invivo; excel_row=11477; Record_ID=skin_sensitization_invivo_2493; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=4966; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Greif 1967; Not available; Not available|Kligman 1971: report to RIFM|Opdyke 1975; Not available; 10.1016/0015-6264(75)90011-5|Gerberick et al. 2001; 11526521; 10.1053/ajcd.2001.23926|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area	5905	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11485; Record_ID=skin_sensitization_invivo_2482; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=5.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area; Response=5905; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=RIFM 2001; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|Api et al. 2008; 18406028; 10.1016/j.yrtph.2007.10.008|Api et al. 2016; 26702986; 10.1016/j.fct.2015.12.013|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area, 5% incidence of positive responses	9197	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11445; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area, 5% incidence of positive responses; Response=9197; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Induction dose per skin area, one positive response	2520	ug/cm2	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11441; Record_ID=skin_sensitization_invivo_2486; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area, one positive response; Response=2520; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Gad et al. (1986; 3715870; 10.1016/0041-008X(86)90419-9|Akkan et al. 2003; Not available; Not available|Griem et al. 2003; 14623479; 10.1016/j.yrtph.2003.07.001|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Max stimulation index	17	ratio	Mouse	Dermal	-	In Vivo; LLNA2013; LLNA	sheet=Data_invivo; excel_row=12888; Record_ID=skin_sensitization_invivo_497; Data_Type=In Vivo; Internal_Data_Source=LLNA2013; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=LLNA; Endpoint=Max stimulation index; Response=17; Response_Unit=Ratio; Species=Mouse; Route=Dermal; Reference=ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Relative reliability score	3	unitless	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11422; Record_ID=skin_sensitization_invivo_2482; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=5.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Relative reliability score; Response=3; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=RIFM 2001; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|Api et al. 2008; 18406028; 10.1016/j.yrtph.2007.10.008|Api et al. 2016; 26702986; 10.1016/j.fct.2015.12.013|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617
NTP_ICE_skin_sensitization	Relative reliability score	2	unitless	Human	Dermal	-	In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test	sheet=Data_invivo; excel_row=11430; Record_ID=skin_sensitization_invivo_2484; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID9020617; Assay=Human Repeat Insult Patch Test; Endpoint=Relative reliability score; Response=2; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Marzulli and Maibach 1980; 7441083; Not available|Akkan et al. 2003; Not available; Not available|Schneider and Akkan 2004; 15135206; 10.1016/j.yrtph.2004.02.002|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9020617; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9020617

ToxRefDB_ToxRefDB_v3_pod.csv 6 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxRefDB_ToxRefDB_v3_pod.csv	LEL	=625	mg/kg bw/day	rat (fischer; Fischer 344)	oral	0 week to 13 week	SUB	study_id=5404; toxval_study_source_id=studyid5404_Adult_F0_F_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=5; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5
ToxRefDB_ToxRefDB_v3_pod.csv	LEL	=900	mg/kg bw/day	mouse (b6c3f1; B6C3F1)	oral	0 week to 103 week	CHR	study_id=5407; toxval_study_source_id=studyid5407_Adult_F0_F_systemic; toxval_effect_list=pathology microscopic-liver-adenoma/carcinoma combined|in life observation-body weight-body weight; dose_level=2; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5
ToxRefDB_ToxRefDB_v3_pod.csv	NEL	=300	mg/kg bw/day	rat (fischer; Fischer 344)	oral	0 week to 13 week	SUB	study_id=5404; toxval_study_source_id=studyid5404_Adult_F0_F_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=4; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5
ToxRefDB_ToxRefDB_v3_pod.csv	NEL	=150	mg/kg bw/day	rat (fischer; Fischer 344)	oral	0 week to 13 week	SUB	study_id=5404; toxval_study_source_id=studyid5404_Adult_F0_M_systemic; toxval_effect_list=in life observation-body weight-body weight; dose_level=3; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5
ToxRefDB_ToxRefDB_v3_pod.csv	NEL	=450	mg/kg bw/day	mouse (b6c3f1; B6C3F1)	oral	0 week to 103 week	CHR	study_id=5407; toxval_study_source_id=studyid5407_Adult_F0_F_systemic; toxval_effect_list=in life observation-body weight-body weight|pathology microscopic-liver-adenoma/carcinoma combined; dose_level=1; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5
ToxRefDB_ToxRefDB_v3_pod.csv	NEL	>0	mg/kg bw/day	mouse (b6c3f1; B6C3F1)	oral	0 week to 103 week	CHR	study_id=5407; toxval_study_source_id=studyid5407_Adult_F0_M_systemic; toxval_effect_list=pathology microscopic-liver-hepatocellular carcinoma|pathology microscopic-liver-hepatocellular adenoma; dose_level=0; study_year=1983; study_citation=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; dsstox_substance_id=DTXSID9020617; admin_method=Feed; cas_source=toxval_ToxRefDB.xlsx:DTXSID; blob_url=https://clowder.edap-cluster.com/files/688cbadae4b02565bc3f8c07/blob; blob_sha256=69dd2da06ffc6a98a1bed684c347d8b2f31e6d35d607d4f2f83ebb6845a708d5

ToxValDB_ECOTOX 6 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxValDB_ECOTOX	LOEL	=5	%	Rat	dermal	acute; 0.0833 days	acute	LONG_REF=J. Pharm. Pharmacol.55(5): 593-601 Fang,J.Y., C.F. Hung, H.C. Chiu, J.J. Wang, and T.F. Chan Efficacy and Irritancy of Enhancers on the In-Vitro and In-Vivo Percutaneous Absorption of Curcumin [Erratum to Efficacy and Irritancy of Enhancers on the In-Vitro and In-Vivo Percutaneous Absorption of Curcumin 2003; TITLE=Efficacy and Irritancy of Enhancers on the In-Vitro and In-Vivo Percutaneous Absorption of Curcumin [Erratum to Efficacy and Irritancy of Enhancers on the In-Vitro and In-Vivo Percutaneous Absorption of Curcumin; AUTHOR=Fang,J.Y., C.F. Hung, H.C. Chiu, J.J. Wang, and T.F. Chan; DOI=10.1211/002235703765344496; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=100249; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2003; ORIGINAL_YEAR=2003; TOXICOLOGICAL_EFFECT=Physiology: Permeability, tissue, membrane|Physiology: Water loss; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15597708:unknown:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=c80eb964ee3d71a38bf90c374b7510b4
ToxValDB_ECOTOX	LOEL	=20	%	Mouse	dermal	short-term; 16 days	short-term	LONG_REF=Contact Dermatitis15(1): 17-23 Maisey,J., and K. Miller Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers 1986; TITLE=Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers; AUTHOR=Maisey,J., and K. Miller; DOI=10.1111/j.1600-0536.1986.tb01255.x; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=81179; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1986; ORIGINAL_YEAR=1986; TOXICOLOGICAL_EFFECT=Immunological: Thickness; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15602839_15602840:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=09a8a0b71146f8f68e4f8c8a40aceac7
ToxValDB_ECOTOX	LOEL	=25	% v/v	Mouse	dermal	short-term; 3 days	short-term	LONG_REF=Arch. Toxicol.74(12): 733-744 Ulrich,P., J. Streich, and W. Suter Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced 2001; TITLE=Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced; AUTHOR=Ulrich,P., J. Streich, and W. Suter; DOI=10.1007/s002040000192; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=112411; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2001; ORIGINAL_YEAR=2001; TOXICOLOGICAL_EFFECT=Cell(s): Number of cells|Morphology: Weight; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology|other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15594433_15599281_15605212_15605213:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=1a5f4fd685512d7a40136f1287137d0e
ToxValDB_ECOTOX	NOEL	=35	% v/v	Mouse	dermal	short-term; 3 days	short-term	LONG_REF=Arch. Toxicol.74(12): 733-744 Ulrich,P., J. Streich, and W. Suter Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced 2001; TITLE=Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced; AUTHOR=Ulrich,P., J. Streich, and W. Suter; DOI=10.1007/s002040000192; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=112411; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2001; ORIGINAL_YEAR=2001; TOXICOLOGICAL_EFFECT=Cell(s): Number of cells|Morphology: Weight; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology|other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15594433_15599281_15605212_15605213:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=648513d40e0f0c0cf333d9371669ed26
ToxValDB_ECOTOX	NOEL	=10	%	Mouse	dermal	short-term; 16 days	short-term	LONG_REF=Contact Dermatitis15(1): 17-23 Maisey,J., and K. Miller Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers 1986; TITLE=Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers; AUTHOR=Maisey,J., and K. Miller; DOI=10.1111/j.1600-0536.1986.tb01255.x; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=81179; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1986; ORIGINAL_YEAR=1986; TOXICOLOGICAL_EFFECT=Immunological: Thickness; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15602839_15602840:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=2d15d3f3be9608ce6af5598b4593c92a
ToxValDB_ECOTOX	NOEL	=5	% v/v	Mouse	dermal	short-term; 3 days	short-term	LONG_REF=Arch. Toxicol.74(12): 733-744 Ulrich,P., J. Streich, and W. Suter Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced 2001; TITLE=Intralaboratory Validation of Alternative Endpoints in the Murine Local Lymph Node Assay for the Identification of Contact Allergic Potential: Primary Ear Skin Irritation and Ear-Draining Lymph Node Hyperplasia Induced; AUTHOR=Ulrich,P., J. Streich, and W. Suter; DOI=10.1007/s002040000192; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=112411; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2001; ORIGINAL_YEAR=2001; TOXICOLOGICAL_EFFECT=Cell(s): Number of cells|Morphology: Weight; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology|other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15594433_15599281_15605212_15605213:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=7bdf58d21253c49975cca6f0462dcd4e

ToxValDB_EFSA 3 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxValDB_EFSA	NOAEL	=300	mg/kg bw/day	Rat	oral	chronic; 103 weeks	chronic	LONG_REF=EFSA FEEDAP (2011). Scientific Opinion on the safety and efficacy of allylhydroxybenzenes (chemical group 18) when used as flavourings for all animal species. doi:10.2903/j.efsa.2011.2440.; TITLE=Scientific Opinion on the safety and efficacy of allylhydroxybenzenes (chemical group 18) when used as flavourings for all animal species; AUTHOR=EFSA FEEDAP; DOI=doi:10.2903/j.efsa.2011.2440; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2011; ORIGINAL_YEAR=2011; TOXICOLOGICAL_EFFECT=body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=EFSA:15614095:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_726f822501c5206dbcac9326d4f9e2cf
ToxValDB_EFSA	NOAEL	=100	mg/kg bw/day	Rat	oral	-	reproduction developmental	LONG_REF=EFSA (2012). Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil. doi:10.2903/j.efsa.2012.2506.; TITLE=Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil; AUTHOR=EFSA; DOI=doi:10.2903/j.efsa.2012.2506; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=EFSA_dup_-_15614096_15614108:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_edceeb46a188fcf3ad49c103b7ce872f
ToxValDB_EFSA	NOEL	=250	mg/kg bw/day	Rat	oral	-	developmental	LONG_REF=EFSA (2012). Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol. doi:10.2903/j.efsa.2012.2914.; TITLE=Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol; AUTHOR=EFSA; DOI=doi:10.2903/j.efsa.2012.2914; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=development; TOXICOLOGICAL_EFFECT_CATEGORY=development; STUDY_GROUP=EFSA:15614103:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9b88016da5ec7364d3f9ca5d5db414ec

ToxValDB_GESTIS_DNEL 1 endpoint

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxValDB_GESTIS_DNEL	DNEL systemic	=21.2	mg/m3	Human	inhalation	-	Toxicity Value	STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15632106:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a4977441a57950de5400aeb7af991981

ToxValDB_ToxRefDB 5 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxValDB_ToxRefDB	LEL	=625	mg/kg bw/day	Rat	oral	subchronic; 13 weeks	subchronic	LONG_REF=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; TITLE=Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; AUTHOR=NTP; EXTERNAL_SOURCE_ID=5404; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1983; ORIGINAL_YEAR=1983; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15709153_15709154:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_3a0972f4e1948e881aa7272ce095b206
ToxValDB_ToxRefDB	LEL	=900	mg/kg bw/day	Mouse	oral	chronic; 103 weeks	chronic	LONG_REF=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; TITLE=Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; AUTHOR=NTP; EXTERNAL_SOURCE_ID=5407; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1983; ORIGINAL_YEAR=1983; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight|systemic: pathology microscopic-liver-adenoma/carcinoma combined; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|cancer; STUDY_GROUP=ToxRefDB_dup_-_15709163_15709164_15709165_15709166:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ee5bf1adacae3c2a51f0bcbab2760c21
ToxValDB_ToxRefDB	NEL	=300	mg/kg bw/day	Rat	oral	subchronic; 13 weeks	subchronic	LONG_REF=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; TITLE=Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; AUTHOR=NTP; EXTERNAL_SOURCE_ID=5404; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1983; ORIGINAL_YEAR=1983; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15709153_15709154:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5dc0569cdc96497082e6842af2e8e772
ToxValDB_ToxRefDB	NEL	=150	mg/kg bw/day	Rat	oral	subchronic; 13 weeks	subchronic	LONG_REF=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; TITLE=Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_13-week study_Rats; AUTHOR=NTP; EXTERNAL_SOURCE_ID=5404; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1983; ORIGINAL_YEAR=1983; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ToxRefDB_dup_-_15709155_15709156_15709157_15709158:M:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6e3f24ec88b9bea717e715b045418bee
ToxValDB_ToxRefDB	NEL	=450	mg/kg bw/day	Mouse	oral	chronic; 103 weeks	chronic	LONG_REF=NTP_1983_Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; TITLE=Carcinogenesis studies of eugenol (CAS No. 97-53-0) in F344/N rats and B6C3F1 mice (feed studies)_2-year study_Mice; AUTHOR=NTP; EXTERNAL_SOURCE_ID=5407; EXTERNAL_SOURCE_ID_DESC=ToxRefDB Study ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66bca4a3e4b0a7c65d2a792a; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://github.com/USEPA/CompTox-ToxRefDB; YEAR=1983; ORIGINAL_YEAR=1983; TOXICOLOGICAL_EFFECT=systemic: in life observation-body weight-body weight|systemic: pathology microscopic-liver-adenoma/carcinoma combined; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|cancer; STUDY_GROUP=ToxRefDB_dup_-_15709163_15709164_15709165_15709166:F:F0adult; QC_CATEGORY=Data source QC'd by data provider prior to ToxRefDB import; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4c12de9186643415d54c142ebd66921c

ToxValDB_WHO_JECFA_ADI 1 endpoint

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
ToxValDB_WHO_JECFA_ADI	ADI	<=2.5	mg/kg	Human	oral	-	Toxicity Value	STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/650af529e4b0d99f5a8736e3; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/; SUBSOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/977; YEAR=2005; ORIGINAL_YEAR=2005; STUDY_GROUP=WHO JECFA ADI:15715256:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_559730b60bf84a184d65c1f7c9c58755

openFDA substances 4 endpoints

Source	Endpoint Type	Value	Unit	Species	Route	Duration	Study Type	Reference
openFDA substances	FDA UNII substance identifier	3T8H1794QW	UNII	-	-	-	chemical	{"approval_status":null,"molecular_formula":"C10H12O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3T8H1794QW"}
openFDA substances	FDA UNII substance identifier	3T8H1794QW	UNII	-	-	-	chemical	{"approval_status":null,"molecular_formula":"C10H12O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3T8H1794QW"}
openFDA substances	FDA UNII substance identifier	3T8H1794QW	UNII	-	-	-	chemical	{"approval_status":null,"molecular_formula":"C10H12O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3T8H1794QW"}
openFDA substances	FDA UNII substance identifier	3T8H1794QW	UNII	-	-	-	chemical	{"approval_status":null,"molecular_formula":"C10H12O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3T8H1794QW"}