Is Esculetin safe in cosmetics?
Esculetin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Esculetin
INCI: ESCULETIN
Esculetin (CAS 305-01-1 [^1_5]) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 305-01-1 [^1_5] →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific 21 CFR restriction; not CIR-reviewed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Esculetin.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Esculetin.
Frequently Asked Questions
Is Esculetin allowed in the EU?
Esculetin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Esculetin do in cosmetics?
Esculetin functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 305-01-1 [^1_5].
Compliance Tools
Check Esculetin compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
Excellent
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Excellent
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
Excellent
Same category
Skin Conditioning
Acetylneuraminic Acid
Excellent
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
Excellent
Same category
Skin Conditioning, Hair Conditioning;...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
Moderate
Similar safety
Skin/hair conditioning (peptide-based...
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-Trimethyl-2-Naphthol
Moderate
Similar safety
Fragrance ingredient
1,2,3,4,4a,7,8,8a-Octahydro-2,4a,5,8a-Tetramethyl-Naphthyl Formate
Moderate
Similar safety
Fragrance ingredient
Carnosine
Excellent
Chemical family
Antioxidant; anti-pollution active; A...
L-Carnosine
Excellent
Chemical family
Skin conditioning, Antioxidant
ETHOXY-METHOXYMETHYL-PHENOL
Good
Browse nearby
Perfuming
Is Esculetin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Esculetin in your formulation.