Ellagic Acid Glucoside

INCI: ELLAGIC ACID

Ellagic Acid Glucoside (CAS Parent ellagic acid: 476-66-4. The glucoside form does not have a widely established unique CAS in cosmetic databases) is a cosmetic cosmetic ingredient functioning as Skin conditioning, skin brightening, antioxidant, anti-aging, astringent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS Parent ellagic acid: 476-66-4. The glucoside form does not have a widely established unique CAS in cosmetic databases →

Auto-generated CPSR Part A draft with source citations
CAS Number
Parent ellagic acid: 476-66-4. The glucoside form does not have a widely established unique CAS in cosmetic databases
View industrial chemical safety profile →
Function
Skin conditioning, skin brightening, antioxidant, anti-aging, astringent
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted with no FDA restriction. GRAS as food additive.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ellagic Acid Glucoside.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"cas_number": "476-66-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
anti_aging
{"anti_aging_claim": "brightening, antioxidant-protection", "mechanism_of_action": "Bioactive compound, specialized mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "12", "sample_size": "35", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "…
anti_pollution
{"cas_number": "476-66-4", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation…
antioxidant
{"cas_number": "476-66-4", "antioxidant_class": "polyphenol", "chemical_subclass": "dimerized gallic acid", "molecular_weight_daltons": "302.19", "orac_value_umol_te_per_g": "14200", "dpph_radical_scavenging_ic50_ug_per_ml": "20-35", "abts_trolox_equivalent": "0.95", "singlet_oxygen_quenching": "high", "superoxide_dismutase_mimetic": "moderate", "hydroxyl_radical_scavenging": "high", "lipid_peroxi…
concentration
{"min_concentration_pct": "0.1", "max_concentration_pct": "1.0", "typical_concentration_pct": "0.5", "product_type": "Moisturizer", "function_at_concentration": "Brightening", "source": "Clinical literature"}
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "120", "estimated_cost_per_kg_usd_high": "220", "natural_premium_markup_pct": "150", "organic_certified_premium_pct": "280", "supply_chain_volatility": "medium", "primary_source_region": "China/India", "synthetic_vs_natural_cost_ratio": "2.5", "bulk_discount_threshold_kg": "10", "seasonal_price_variation": "medium", "commodity_or_specialty"…
depigmentation
{"cas_number": "476-66-4", "ingredient_class": "tyrosinase_inhibitor", "primary_mechanism_of_action": "Polyphenol from berries/pomegranate; copper chelation tyrosinase inhibition", "secondary_mechanisms": "Variable", "molecular_target": "tyrosinase", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction…
interactions
{"ingredient_2": "Niacinamide", "interaction_type": "synergistic", "severity": "beneficial", "effect": "Dual brightening, antioxidant protection", "recommendation": "Compatible; gentle brightening combination", "data_source": "Formulation science literature, dermatological research, cosmetic chemistry best practices", "last_updated": "2026-03-05"}

Expert Verdict

Expert safety assessment and concern-level summary for Ellagic Acid Glucoside.

Frequently Asked Questions

Is Ellagic Acid Glucoside safe in cosmetics?

Ellagic Acid Glucoside has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Ellagic Acid Glucoside allowed in the EU?

Ellagic Acid Glucoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ellagic Acid Glucoside do in cosmetics?

Ellagic Acid Glucoside functions as: Skin conditioning, skin brightening, antioxidant, anti-aging, astringent. It is classified as a cosmetic ingredient in our database. CAS number: Parent ellagic acid: 476-66-4. The glucoside form does not have a widely established unique CAS in cosmetic databases.

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