| ECHA |
LEL |
>1280 |
ppm |
Rat |
oral |
short-term; 4 days |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca0de4b0a7c65d21ff5e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15838152:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_97b60c3246cdf1c1c534b68897ee529c |
| ECHA |
LOAEL |
=200 |
ppm |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c891e4b0a7c65d219148; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=P0: organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=organ weight; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855752_15856511_15856809_15856909:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2fab0373ee9d781b9584d37319e72d07 |
| ECHA |
LOAEL |
=600 |
mg/kg bw/day |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa57e4b0a7c65d1b55fb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856465_15856796_15862517:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2ddeb2b760c50b1cb66d11868368112f |
| ECHA |
NOAEL |
>7 |
mg/kg bw/day |
Mouse |
oral |
subchronic; 85 days |
subchronic |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaccce4b0a7c65d1c0e23; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15850314:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_1a6114d264e2dd707f8bab9064c836e7 |
| ECHA |
NOAEL |
=36.4574 |
mg/m3 |
Rat |
inhalation |
- |
reproduction developmental |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d17de4b0a7c65d22ed79; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=maternal: body weight and weight gain|maternal: clinical signs|maternal: ophthalmological examination; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|gross pathology; STUDY_GROUP=ECHA IUCLID:15822622:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e4b460c48970673abb2127f645eb0a22 |
| ECHA |
NOAEL |
=50 |
mg/kg bw/day |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa57e4b0a7c65d1b55f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=P0: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855601_15862514_15862515:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a730ab58c9efb19c44bf403d66304cec |
| ECHA |
NOAEL |
=100 |
mg/kg bw/day |
Rabbit |
oral |
- |
reproduction developmental |
GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabb9e4b0a7c65d1bb6f3; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=maternal: body weight and weight gain|maternal: food consumption and compound intake|maternal: mortality; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|food and/or water consumption|mortality/survival; STUDY_GROUP=ECHA IUCLID:15823248:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_3aafaf3c5fb4d18574932554ab98b6d3 |
| ECHA |
NOAEL |
=150 |
mg/kg bw/day |
Rat |
oral |
subchronic (developmental) |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca0de4b0a7c65d21ff86; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15847452:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_0eb2264e0106052c72cfb68a0c676ffb |
| ECHA |
NOAEL |
>240 |
mg/kg bw/day |
Rat |
oral |
short-term; 4 days |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca0de4b0a7c65d21ff8b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15844678:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4e5bfa49206c72d5f934d2777dbbb5ce |
| ECHA |
NOAEL |
=250 |
mg/kg bw/day |
Rabbit |
oral |
- |
developmental |
GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabb9e4b0a7c65d1bb6f3; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15823546:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_918b1f01113e91eb0acf1241447fa4bc |
| ECHA |
NOAEL |
=300 |
mg/kg bw/day |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa57e4b0a7c65d1b55fb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856465_15856796_15862517:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_8fd6c16e9cf60b2cfda97af5f678515e |
| ECHA |
NOAEL |
>=364.574 |
mg/m3 |
Rat |
inhalation |
- |
developmental |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d17de4b0a7c65d22ed79; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID:15821308:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a1e21f7b2d21f6621d5da5c919bcf621 |
| ECHA |
NOAEL |
=1000 |
ppm |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c891e4b0a7c65d219148; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=P0: clinical signs|P0: mortality|P0: body weight and weight gain|P0: water consumption and compound intake; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|mortality/survival; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855752_15856511_15856809_15856909:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_dd27ad180064d383ad588ad67b20ec44 |
| ECHA |
NOAEL |
=2500 |
ppm |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c891e4b0a7c65d219148; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=F1: viability|F1: mortality|F1: body weight and weight gain; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|mortality/survival|reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15858436_15858696:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f779c372804e3fdae9d92cdc93c125ce |
| ECHA |
NOAEL |
=5000 |
ppm |
Rat |
oral |
- |
reproduction developmental |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c891e4b0a7c65d219148; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/9/2?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; TOXICOLOGICAL_EFFECT=P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855752_15856511_15856809_15856909:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_76a2a6580bcc370190fc00fd235aff9d |
| ECHA |
NOEC |
=87.4979 |
mg/m3 |
Rat |
inhalation |
subchronic; 13 weeks |
subchronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829301_15829302:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d5780a1f9fed75fe44ac34da73e15d69 |
| ECHA |
NOEC |
=87.5 |
mg/m3 |
Rat |
inhalation |
subchronic; 13 weeks |
subchronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14464/7/6/3?documentUUID=7092acde-d6fc-4dcf-999b-804700543d36; YEAR=1992; ORIGINAL_YEAR=1992; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829301_15829302:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_41524ed5b68290520df9745794c95d47 |