NOAEL Studies
Emollient
Dimethicone NOAEL Studies
INCI: DIMETHICONE
CAS: 9006-65-9
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
COSMOS_DB 8 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| COSMOS_DB | NOAEL | 500 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 300 | mg/kg bw/day | dog | oral | 183 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 1250 | mg/kg bw/day | mouse | oral | 560 day | Chronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 1000 | mg/kg bw/day | rat | oral | 20 day | Developmental | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 761 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 778 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 8355 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 8136 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
INCHEM_WHO_jecfa_jecmono_v966je01 68 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.60.6 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=7bd3c550663bdc85; raw_unit=mg/kg body weight; context=At its twenty-sixth meeting, the Committee established a temporary ADI of 0-0.6 mg/kg body weight (bw) for sodium aluminium phosphate (Annex 1, reference 59). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-55 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9c5bc0dcc9e528e1; raw_unit=mg/ kg bw; context=At its forty-sixth meeting, the Committee confirmed the group ADI of benzyl derivatives, including benzoic acid and benzyl benzoate, of 0-5 mg/ kg bw as benzoic acid equivalents (Annex 1, reference 122), which was main- tained at its fifty-seventh meeting (Annex 1, reference 154). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-1010 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=1f2557279d14b0ea; raw_unit=mg/kg bw; context=At its eleventh meeting, the Committee assigned vanillin an ADI of 0-10 mg/kg bw (Annex 1, reference 14), which was maintained at the fifty-seventh meeting. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-2525 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=b5fd317403f407f9; raw_unit=mg/kg bw; context=The Committee established a group ADI of 0-25 mg/kg bw 22 for GEGR and glycerol ester of wood rosin (GEWR). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-12.512.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a6f064d1bdffc970; raw_unit=mg/kg bw; context=The Committee withdrew the group ADI for GEGR and GEWR at the cur- rent meeting (see section 3.1.5), and a temporary group ADI for GEGR and GEWR of 0-12.5 mg/kg bw was established, pending the availability of additional compositional information on the GEWR from Pinus elliottii. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-1.51.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=675e8ae3ba0cfe55; raw_unit=mg/kg bw; context=At its eighteenth meeting in 28 1974 (Annex 1, reference 35), the Committee established an ADI of 0-1.5 mg/kg bw for PDMS. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.80.8 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=49724ebbf96329e0; raw_unit=mg/kg bw; context=The Committee withdrew the previously established ADI of 0-1.5 mg/kg bw and, using an additional uncertainty factor of 2, established a temporary ADI of 0-0.8 mg/kg bw for PDMS, pending submission of the results of studies to elucidate the mecha- nism and relevance of the ocular toxicity. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.750.75 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a69bb063fafeb9e2; raw_unit=mg/kg bw; context=At its thirteenth meet- ing, the Committee reviewed these data and established a temporary ADI of 0-0.75 mg/kg bw based on a NOEL1 of 150 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.1250.125 | mg/kg bw/day | Mouse | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=aabe5ab27f318b72; raw_unit=mg/kg bw; context=At its eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-44 | mg/kg bw/day | Rat; Mouse | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=ccdcd8ac3b82887e; raw_unit=mg/kg bw.; context=The results of this study in rats and a reconsideration of the severity of the renal effects observed in the long-term study in mice led the Committee to establish an ADI of 0-4 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-11 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5b64de489c59b25a; raw_unit=mg/kg bw; context=At its thirteenth meeting, the Committee reviewed the available data and established a temporary ADI of 0-1 mg/kg bw based on a NOEL2 of 500 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.50.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=3254b34b4713fd89; raw_unit=mg/kg bw; context=Using the results of that study, the Committee established a temporary ADI of 0-0.5 mg/kg bw based on the absence of any adverse effects at the highest tested dose of 50 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-2.52.5 | mg/kg bw/day | - | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=15a426bf6f2cd35e; raw_unit=mg/kg bw.; context=At the twenty-sixth meeting, the Committee con- sidered new studies on long-term and reproductive toxicity and established an ADI of 0-2.5 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-12.512.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a6f064d1bdffc970; raw_unit=mg/kg bw; context=The Committee withdrew the group ADI for GEGR and GEWR at the cur- rent meeting (see section 3.1.5), and a temporary group ADI for GEGR and GEWR of 0-12.5 mg/kg bw was established, pending the availability of additional compositional information on the GEWR from Pinus elliottii. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-1.51.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=675e8ae3ba0cfe55; raw_unit=mg/kg bw; context=At its eighteenth meeting in 28 1974 (Annex 1, reference 35), the Committee established an ADI of 0-1.5 mg/kg bw for PDMS. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.80.8 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=49724ebbf96329e0; raw_unit=mg/kg bw; context=The Committee withdrew the previously established ADI of 0-1.5 mg/kg bw and, using an additional uncertainty factor of 2, established a temporary ADI of 0-0.8 mg/kg bw for PDMS, pending submission of the results of studies to elucidate the mecha- nism and relevance of the ocular toxicity. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.750.75 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a69bb063fafeb9e2; raw_unit=mg/kg bw; context=At its thirteenth meet- ing, the Committee reviewed these data and established a temporary ADI of 0-0.75 mg/kg bw based on a NOEL1 of 150 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.1250.125 | mg/kg bw/day | Mouse | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=aabe5ab27f318b72; raw_unit=mg/kg bw; context=At its eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-44 | mg/kg bw/day | Rat; Mouse | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=ccdcd8ac3b82887e; raw_unit=mg/kg bw.; context=The results of this study in rats and a reconsideration of the severity of the renal effects observed in the long-term study in mice led the Committee to establish an ADI of 0-4 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-11 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5b64de489c59b25a; raw_unit=mg/kg bw; context=At its thirteenth meeting, the Committee reviewed the available data and established a temporary ADI of 0-1 mg/kg bw based on a NOEL2 of 500 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.50.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=3254b34b4713fd89; raw_unit=mg/kg bw; context=Using the results of that study, the Committee established a temporary ADI of 0-0.5 mg/kg bw based on the absence of any adverse effects at the highest tested dose of 50 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-2.52.5 | mg/kg bw/day | - | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=15a426bf6f2cd35e; raw_unit=mg/kg bw.; context=At the twenty-sixth meeting, the Committee con- sidered new studies on long-term and reproductive toxicity and established an ADI of 0-2.5 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.60.6 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=7bd3c550663bdc85; raw_unit=mg/kg body weight; context=At its twenty-sixth meeting, the Committee established a temporary ADI of 0-0.6 mg/kg body weight (bw) for sodium aluminium phosphate (Annex 1, reference 59). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-55 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9c5bc0dcc9e528e1; raw_unit=mg/ kg bw; context=At its forty-sixth meeting, the Committee confirmed the group ADI of benzyl derivatives, including benzoic acid and benzyl benzoate, of 0-5 mg/ kg bw as benzoic acid equivalents (Annex 1, reference 122), which was main- tained at its fifty-seventh meeting (Annex 1, reference 154). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-1010 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=1f2557279d14b0ea; raw_unit=mg/kg bw; context=At its eleventh meeting, the Committee assigned vanillin an ADI of 0-10 mg/kg bw (Annex 1, reference 14), which was maintained at the fifty-seventh meeting. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-2525 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=b5fd317403f407f9; raw_unit=mg/kg bw; context=The Committee established a group ADI of 0-25 mg/kg bw 22 for GEGR and glycerol ester of wood rosin (GEWR). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-12.512.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a6f064d1bdffc970; raw_unit=mg/kg bw; context=The Committee withdrew the group ADI for GEGR and GEWR at the cur- rent meeting (see section 3.1.5), and a temporary group ADI for GEGR and GEWR of 0-12.5 mg/kg bw was established, pending the availability of additional compositional information on the GEWR from Pinus elliottii. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-1.51.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=675e8ae3ba0cfe55; raw_unit=mg/kg bw; context=At its eighteenth meeting in 28 1974 (Annex 1, reference 35), the Committee established an ADI of 0-1.5 mg/kg bw for PDMS. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.80.8 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=49724ebbf96329e0; raw_unit=mg/kg bw; context=The Committee withdrew the previously established ADI of 0-1.5 mg/kg bw and, using an additional uncertainty factor of 2, established a temporary ADI of 0-0.8 mg/kg bw for PDMS, pending submission of the results of studies to elucidate the mecha- nism and relevance of the ocular toxicity. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.750.75 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=a69bb063fafeb9e2; raw_unit=mg/kg bw; context=At its thirteenth meet- ing, the Committee reviewed these data and established a temporary ADI of 0-0.75 mg/kg bw based on a NOEL1 of 150 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.1250.125 | mg/kg bw/day | Mouse | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=aabe5ab27f318b72; raw_unit=mg/kg bw; context=At its eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-44 | mg/kg bw/day | Rat; Mouse | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=ccdcd8ac3b82887e; raw_unit=mg/kg bw.; context=The results of this study in rats and a reconsideration of the severity of the renal effects observed in the long-term study in mice led the Committee to establish an ADI of 0-4 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-11 | mg/kg bw/day | Rat | oral | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5b64de489c59b25a; raw_unit=mg/kg bw; context=At its thirteenth meeting, the Committee reviewed the available data and established a temporary ADI of 0-1 mg/kg bw based on a NOEL2 of 500 mg/kg bw per day in a long-term feeding study in rats. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-0.50.5 | mg/kg bw/day | - | - | - | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=3254b34b4713fd89; raw_unit=mg/kg bw; context=Using the results of that study, the Committee established a temporary ADI of 0-0.5 mg/kg bw based on the absence of any adverse effects at the highest tested dose of 50 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | ADI | range:0-2.52.5 | mg/kg bw/day | - | - | long-term | Health guidance value | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=15a426bf6f2cd35e; raw_unit=mg/kg bw.; context=At the twenty-sixth meeting, the Committee con- sidered new studies on long-term and reproductive toxicity and established an ADI of 0-2.5 mg/kg bw. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | LOAEL | range:50-7575 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=4c3059c239abb59d; raw_unit=mg/kg bw per day; context=At its current meeting, the Committee noted that the new data did not sub- stantially change the LOAEL range of 50-75 mg/kg bw per day, but one of the studies also provided a NOAEL of 30 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | LOAEL | range:50-7575 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=4c3059c239abb59d; raw_unit=mg/kg bw per day; context=At its current meeting, the Committee noted that the new data did not sub- stantially change the LOAEL range of 50-75 mg/kg bw per day, but one of the studies also provided a NOAEL of 30 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =30 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=560efd8f163686dd; raw_unit=mg/kg bw per day; context=ee concluded that, taking into account the greater bioavailability of aluminium from aluminium citrate than from other alu- minium compounds, it was appropriate to assume that the NOAEL was 30 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =500 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=c89fdbd3ed5d7403; raw_unit=mg/kg bw per day; context=The NOAEL was considered to be 500 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =246 | mg/kg bw/day | - | - | 13-week | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=d85ba13eaea543c5; raw_unit=mg/kg; context=Therefore, the NOAEL was identified as 246 mg/kg 43 bw per day as TOS, the highest dose tested in the 13-week study. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =375 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=61b0bd6213c3725c; raw_unit=mg/kg bw per day; context=The NOAEL for reduced pup body weight was 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =0.2 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9da8efc3b3903859; raw_unit=mg/kg bw per day; context=The Committee established a group PMTDI for fumonisins B1 (FB1), B2 (FB2) and B3 (FB3), alone or in combination, of 2 ug/kg bw on the basis of the NOAEL of 0.2 mg/kg bw per day for kidney toxicity and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =4.28571428571429 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=62bacd8d7dd1fe3b; raw_unit=mg/kg body weight per day; unit_normalization=converted from weekly dose; context=icate-based pearlescent pigments) N, Tb The Committee established a provisional tolerable weekly intake (PTWI) of 2 mg/kg body weight based on a no-observed-adverse- effect level (NOAEL) of 30 mg/kg body weight per day and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =246 | mg/kg bw/day | - | - | 13-week | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=d85ba13eaea543c5; raw_unit=mg/kg; context=Therefore, the NOAEL was identified as 246 mg/kg 43 bw per day as TOS, the highest dose tested in the 13-week study. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =375 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=61b0bd6213c3725c; raw_unit=mg/kg bw per day; context=The NOAEL for reduced pup body weight was 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =0.2 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9da8efc3b3903859; raw_unit=mg/kg bw per day; context=The Committee established a group PMTDI for fumonisins B1 (FB1), B2 (FB2) and B3 (FB3), alone or in combination, of 2 ug/kg bw on the basis of the NOAEL of 0.2 mg/kg bw per day for kidney toxicity and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =4.28571428571429 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=62bacd8d7dd1fe3b; raw_unit=mg/kg body weight per day; unit_normalization=converted from weekly dose; context=icate-based pearlescent pigments) N, Tb The Committee established a provisional tolerable weekly intake (PTWI) of 2 mg/kg body weight based on a no-observed-adverse- effect level (NOAEL) of 30 mg/kg body weight per day and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =30 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=560efd8f163686dd; raw_unit=mg/kg bw per day; context=ee concluded that, taking into account the greater bioavailability of aluminium from aluminium citrate than from other alu- minium compounds, it was appropriate to assume that the NOAEL was 30 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =500 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=c89fdbd3ed5d7403; raw_unit=mg/kg bw per day; context=The NOAEL was considered to be 500 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =246 | mg/kg bw/day | - | - | 13-week | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=d85ba13eaea543c5; raw_unit=mg/kg; context=Therefore, the NOAEL was identified as 246 mg/kg 43 bw per day as TOS, the highest dose tested in the 13-week study. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =375 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=61b0bd6213c3725c; raw_unit=mg/kg bw per day; context=The NOAEL for reduced pup body weight was 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =0.2 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9da8efc3b3903859; raw_unit=mg/kg bw per day; context=The Committee established a group PMTDI for fumonisins B1 (FB1), B2 (FB2) and B3 (FB3), alone or in combination, of 2 ug/kg bw on the basis of the NOAEL of 0.2 mg/kg bw per day for kidney toxicity and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOAEL | =4.28571428571429 | mg/kg bw/day | - | - | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=62bacd8d7dd1fe3b; raw_unit=mg/kg body weight per day; unit_normalization=converted from weekly dose; context=icate-based pearlescent pigments) N, Tb The Committee established a provisional tolerable weekly intake (PTWI) of 2 mg/kg body weight based on a no-observed-adverse- effect level (NOAEL) of 30 mg/kg body weight per day and application of an uncertainty factor of 100. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =25 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=903115d02dc86c59; raw_unit=mg/kg bw per day; context=s eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =500 | mg/kg bw/day | Rat | - | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5e029ce96f85ff01; raw_unit=mg/kg bw per day; context=The Committee noted that the long-term study in rats showed no adverse effects in the kidneys and had a NOEL of 500 mg/kg bw per day based on reduced body weight gain at higher doses. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =375 | mg/kg bw/day | Mouse | oral | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=c2237fb3b721e840; raw_unit=mg/kg bw per day; context=The ADI was derived by applying a 100- fold uncertainty factor to the higher NOEL from the mouse dietary study, which was equivalent to 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =7900 | mg/kg bw/day | Rat | oral | 90-day | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9012666e4995dd4d; raw_unit=mg/kg bw per day; context=Evaluation At the sixty-fifth meeting, the Committee evaluated a 90-day oral toxicity study in the rat with pullulan (relative molecular mass, 200 000 Da) in which the NOEL was 7900 mg/kg bw per day (the highest dose tested). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | range:1000-15001500 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=dfd4e5b8c2d01b33; raw_unit=mg/kg bw per day; context=The Committee established an ADI of 0-10 mg/kg bw based on a NOEL of 10 000 mg/kg in the diet (equivalent to a range of 1000-1500 mg/kg bw per day) in the long-term study in mice. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =25 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=903115d02dc86c59; raw_unit=mg/kg bw per day; context=s eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =500 | mg/kg bw/day | Rat | - | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5e029ce96f85ff01; raw_unit=mg/kg bw per day; context=The Committee noted that the long-term study in rats showed no adverse effects in the kidneys and had a NOEL of 500 mg/kg bw per day based on reduced body weight gain at higher doses. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =375 | mg/kg bw/day | Mouse | oral | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=c2237fb3b721e840; raw_unit=mg/kg bw per day; context=The ADI was derived by applying a 100- fold uncertainty factor to the higher NOEL from the mouse dietary study, which was equivalent to 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =7900 | mg/kg bw/day | Rat | oral | 90-day | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9012666e4995dd4d; raw_unit=mg/kg bw per day; context=Evaluation At the sixty-fifth meeting, the Committee evaluated a 90-day oral toxicity study in the rat with pullulan (relative molecular mass, 200 000 Da) in which the NOEL was 7900 mg/kg bw per day (the highest dose tested). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | range:1000-15001500 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=dfd4e5b8c2d01b33; raw_unit=mg/kg bw per day; context=The Committee established an ADI of 0-10 mg/kg bw based on a NOEL of 10 000 mg/kg in the diet (equivalent to a range of 1000-1500 mg/kg bw per day) in the long-term study in mice. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =25 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=903115d02dc86c59; raw_unit=mg/kg bw per day; context=s eighteenth meeting, the Committee considered an additional long-term feeding study in mice that had become available and revised the temporary ADI to 0-0.125 mg/kg bw based on a NOEL of 25 mg/kg bw per day (this NOEL assumed 500 mg/kg in the diet to be equivalent to 25 mg/kg bw per day). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =500 | mg/kg bw/day | Rat | - | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=5e029ce96f85ff01; raw_unit=mg/kg bw per day; context=The Committee noted that the long-term study in rats showed no adverse effects in the kidneys and had a NOEL of 500 mg/kg bw per day based on reduced body weight gain at higher doses. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =375 | mg/kg bw/day | Mouse | oral | - | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=c2237fb3b721e840; raw_unit=mg/kg bw per day; context=The ADI was derived by applying a 100- fold uncertainty factor to the higher NOEL from the mouse dietary study, which was equivalent to 375 mg/kg bw per day. |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | =7900 | mg/kg bw/day | Rat | oral | 90-day | Subchronic toxicity | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=9012666e4995dd4d; raw_unit=mg/kg bw per day; context=Evaluation At the sixty-fifth meeting, the Committee evaluated a 90-day oral toxicity study in the rat with pullulan (relative molecular mass, 200 000 Da) in which the NOEL was 7900 mg/kg bw per day (the highest dose tested). |
| INCHEM_WHO_jecfa_jecmono_v966je01 | NOEL | range:1000-15001500 | mg/kg bw/day | Mouse | oral | long-term | Toxicology study | document_id=jecfa_jecmono_v966je01; title=Evaluation of Certain Food Additives and Contaminants; path=mirror/documents/jecfa/jecmono/v966je01.pdf; row_hash=dfd4e5b8c2d01b33; raw_unit=mg/kg bw per day; context=The Committee established an ADI of 0-10 mg/kg bw based on a NOEL of 10 000 mg/kg in the diet (equivalent to a range of 1000-1500 mg/kg bw per day) in the long-term study in mice. |
openFDA substances 40 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 92RU3N3Y1O | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"92RU3N3Y1O"} |
| openFDA substances | FDA UNII substance identifier | TYU5GP6XGE | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"TYU5GP6XGE"} |
| openFDA substances | FDA UNII substance identifier | H8YMB5QY0D | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"H8YMB5QY0D"} |
| openFDA substances | FDA UNII substance identifier | concept | identifier | - | - | - | concept | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null} |
| openFDA substances | FDA UNII substance identifier | D1R3R4B8M8 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"D1R3R4B8M8"} |
| openFDA substances | FDA UNII substance identifier | 2Y53S6ATLU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"2Y53S6ATLU"} |
| openFDA substances | FDA UNII substance identifier | 5L1VVC3K8O | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5L1VVC3K8O"} |
| openFDA substances | FDA UNII substance identifier | RGS4T2AS00 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RGS4T2AS00"} |
| openFDA substances | FDA UNII substance identifier | RO266O364U | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RO266O364U"} |
| openFDA substances | FDA UNII substance identifier | MCU2324216 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"MCU2324216"} |
| openFDA substances | FDA UNII substance identifier | 92RU3N3Y1O | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"92RU3N3Y1O"} |
| openFDA substances | FDA UNII substance identifier | 92RU3N3Y1O | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"92RU3N3Y1O"} |
| openFDA substances | FDA UNII substance identifier | TYU5GP6XGE | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"TYU5GP6XGE"} |
| openFDA substances | FDA UNII substance identifier | H8YMB5QY0D | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"H8YMB5QY0D"} |
| openFDA substances | FDA UNII substance identifier | TYU5GP6XGE | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"TYU5GP6XGE"} |
| openFDA substances | FDA UNII substance identifier | H8YMB5QY0D | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"H8YMB5QY0D"} |
| openFDA substances | FDA UNII substance identifier | concept | identifier | - | - | - | concept | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null} |
| openFDA substances | FDA UNII substance identifier | concept | identifier | - | - | - | concept | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null} |
| openFDA substances | FDA UNII substance identifier | D1R3R4B8M8 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"D1R3R4B8M8"} |
| openFDA substances | FDA UNII substance identifier | D1R3R4B8M8 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"D1R3R4B8M8"} |
| openFDA substances | FDA UNII substance identifier | 2Y53S6ATLU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"2Y53S6ATLU"} |
| openFDA substances | FDA UNII substance identifier | 2Y53S6ATLU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"2Y53S6ATLU"} |
| openFDA substances | FDA UNII substance identifier | 92RU3N3Y1O | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"92RU3N3Y1O"} |
| openFDA substances | FDA UNII substance identifier | TYU5GP6XGE | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"TYU5GP6XGE"} |
| openFDA substances | FDA UNII substance identifier | H8YMB5QY0D | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"H8YMB5QY0D"} |
| openFDA substances | FDA UNII substance identifier | concept | identifier | - | - | - | concept | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"concept","unii_code":null} |
| openFDA substances | FDA UNII substance identifier | 5L1VVC3K8O | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5L1VVC3K8O"} |
| openFDA substances | FDA UNII substance identifier | 5L1VVC3K8O | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5L1VVC3K8O"} |
| openFDA substances | FDA UNII substance identifier | RGS4T2AS00 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RGS4T2AS00"} |
| openFDA substances | FDA UNII substance identifier | RGS4T2AS00 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RGS4T2AS00"} |
| openFDA substances | FDA UNII substance identifier | D1R3R4B8M8 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"D1R3R4B8M8"} |
| openFDA substances | FDA UNII substance identifier | RO266O364U | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RO266O364U"} |
| openFDA substances | FDA UNII substance identifier | RO266O364U | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RO266O364U"} |
| openFDA substances | FDA UNII substance identifier | 2Y53S6ATLU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"2Y53S6ATLU"} |
| openFDA substances | FDA UNII substance identifier | 5L1VVC3K8O | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5L1VVC3K8O"} |
| openFDA substances | FDA UNII substance identifier | RGS4T2AS00 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RGS4T2AS00"} |
| openFDA substances | FDA UNII substance identifier | RO266O364U | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"RO266O364U"} |
| openFDA substances | FDA UNII substance identifier | MCU2324216 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"MCU2324216"} |
| openFDA substances | FDA UNII substance identifier | MCU2324216 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"MCU2324216"} |
| openFDA substances | FDA UNII substance identifier | MCU2324216 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"MCU2324216"} |