NOAEL Studies Cosmetic Ingredient

Diisopropylamine NOAEL Studies

INCI: DIISOPROPYLAMINE

CAS: 108-18-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip 21 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 15 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=67858ba5-9408-4246-80dd-96215457d9a9
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 50 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=f550d114-70b4-4fa5-8d74-2ee8147523d7
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 300 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=d06f2935-7d61-425b-95d1-35db799e3bf5
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 1000 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=dda86d89-b65a-45b7-ad79-177b0dcb7a50
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL >=150 mg/kg bw/day rat - - short-term repeated dose toxicity: dermal dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=e969a816-4736-4992-9a3a-e50e4dda0a6e_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=e969a816-4736-4992-9a3a-e50e4dda0a6e/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityDermal; literature=Name=Unnamed; ReferenceYear=1987; ReportDate=1987-12-08; basis=other:; key_result=false; entry_uuid=732a4922-eb6f-43b3-8988-83ab74f70a53
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 30 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=62f10084-3f73-4d14-8ba5-3d5e86c39450_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=62f10084-3f73-4d14-8ba5-3d5e86c39450/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1990; basis=other:; key_result=false; entry_uuid=92d30153-5ccc-4e80-814c-fee756a5c1a0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 15 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=67858ba5-9408-4246-80dd-96215457d9a9
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 50 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=f550d114-70b4-4fa5-8d74-2ee8147523d7
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 300 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=d06f2935-7d61-425b-95d1-35db799e3bf5
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 1000 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=dda86d89-b65a-45b7-ad79-177b0dcb7a50
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL >=150 mg/kg bw/day rat - - short-term repeated dose toxicity: dermal dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=e969a816-4736-4992-9a3a-e50e4dda0a6e_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=e969a816-4736-4992-9a3a-e50e4dda0a6e/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityDermal; literature=Name=Unnamed; ReferenceYear=1987; ReportDate=1987-12-08; basis=other:; key_result=false; entry_uuid=732a4922-eb6f-43b3-8988-83ab74f70a53
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 30 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=62f10084-3f73-4d14-8ba5-3d5e86c39450_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=62f10084-3f73-4d14-8ba5-3d5e86c39450/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1990; basis=other:; key_result=false; entry_uuid=92d30153-5ccc-4e80-814c-fee756a5c1a0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 15 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=67858ba5-9408-4246-80dd-96215457d9a9
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 50 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=08c0243e-d74e-4f81-b6c0-b69f020c8c6f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=08c0243e-d74e-4f81-b6c0-b69f020c8c6f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=f550d114-70b4-4fa5-8d74-2ee8147523d7
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 300 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=d06f2935-7d61-425b-95d1-35db799e3bf5
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 1000 mg/kg bw/day rat oral: gavage - developmental toxicity dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=d3984031-4f53-4666-b277-800ebef1230f_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=d3984031-4f53-4666-b277-800ebef1230f/49356119-15da-4a23-ae4c-87164057416c; document_subtype=DevelopmentalToxicityTeratogenicity; literature=Name=Unnamed; ReferenceYear=2009; ReportDate=2009-12-14; basis=other:; key_result=false; entry_uuid=dda86d89-b65a-45b7-ad79-177b0dcb7a50
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL >=150 mg/kg bw/day rat - - short-term repeated dose toxicity: dermal dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=e969a816-4736-4992-9a3a-e50e4dda0a6e_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=e969a816-4736-4992-9a3a-e50e4dda0a6e/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityDermal; literature=Name=Unnamed; ReferenceYear=1987; ReportDate=1987-12-08; basis=other:; key_result=false; entry_uuid=732a4922-eb6f-43b3-8988-83ab74f70a53
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 30 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=62f10084-3f73-4d14-8ba5-3d5e86c39450_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=62f10084-3f73-4d14-8ba5-3d5e86c39450/49356119-15da-4a23-ae4c-87164057416c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1990; basis=other:; key_result=false; entry_uuid=92d30153-5ccc-4e80-814c-fee756a5c1a0
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL >=150 mg/kg bw/day rat oral: gavage - toxicity to reproduction: other studies dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=b95619d9-80bc-4e56-8a6e-8ec6279379f1_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=b95619d9-80bc-4e56-8a6e-8ec6279379f1/49356119-15da-4a23-ae4c-87164057416c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=fd6182d9-ef2d-4634-997c-b2d3f587bdd1
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL >=150 mg/kg bw/day rat oral: gavage - toxicity to reproduction: other studies dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=b95619d9-80bc-4e56-8a6e-8ec6279379f1_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=b95619d9-80bc-4e56-8a6e-8ec6279379f1/49356119-15da-4a23-ae4c-87164057416c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=fd6182d9-ef2d-4634-997c-b2d3f587bdd1
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL >=150 mg/kg bw/day rat oral: gavage - toxicity to reproduction: other studies dossier=49356119-15da-4a23-ae4c-87164057416c.i6z; document=b95619d9-80bc-4e56-8a6e-8ec6279379f1_49356119-15da-4a23-ae4c-87164057416c.i6d; document_key=b95619d9-80bc-4e56-8a6e-8ec6279379f1/49356119-15da-4a23-ae4c-87164057416c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1994-05-06; basis=other:; key_result=false; entry_uuid=fd6182d9-ef2d-4634-997c-b2d3f587bdd1
NTP_ICE_acute_inhalation 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 10.6218 mg/L - Inhalation Duration=0.5 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=5101; Record_ID=acute_inhalation_519; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID9025085; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=10.6218; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13145/7/3/3/?documentUUID=a60bdb46-6f46-4e5a-9247-2bc1c6cd714c; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9025085
NTP_ICE_acute_inhalation LC50 >4.1362 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=5102; Record_ID=acute_inhalation_521; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID9025085; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=4.1362; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13145/7/3/3/?documentUUID=884154b4-5ae0-4e95-8132-503a0d4cac28; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9025085
NTP_ICE_acute_inhalation LC50 4.8 mg/L - Inhalation Duration=2 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=5103; Record_ID=acute_inhalation_1135; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID9025085; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=4.8; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9025085
NTP_ICE_acute_inhalation LC50 5.35 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=5104; Record_ID=acute_inhalation_520; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID9025085; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=5.35; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13145/7/3/3/?documentUUID=cead34d3-5d66-4d4d-9699-aef6915a650a; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID9025085
NTP_ICE_acute_oral 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =310 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_705; row=15634; data_type=In Vivo; mixture=Chemical; chemical_name=Diisopropylamine; preferred_name=Diisopropylamine; dtxsid=DTXSID9025085; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9025085; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 =420 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_706; row=15635; data_type=In Vivo; mixture=Chemical; chemical_name=Diisopropylamine; preferred_name=Diisopropylamine; dtxsid=DTXSID9025085; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9025085; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 =540 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_707; row=15636; data_type=In Vivo; mixture=Chemical; chemical_name=Diisopropylamine; preferred_name=Diisopropylamine; dtxsid=DTXSID9025085; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9025085; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 =770 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_708; row=15637; data_type=In Vivo; mixture=Chemical; chemical_name=Diisopropylamine; preferred_name=Diisopropylamine; dtxsid=DTXSID9025085; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025085; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID9025085; source_file=acute_oral.xlsx
ToxValDB_DOE_Protective_Action_Criteria 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_DOE_Protective_Action_Criteria LEL =45526.7 mg/m3 Human inhalation - acute LONG_REF=U.S. Department of Energy (DOE) Protective Action Criteria (PAC). 2023. PAC Chemical Database. Updated 11 October 2023. Available: https://edms3.energy.gov/pac/ (Accessed November 16, 2023); TITLE=U.S. Department of Energy (DOE) Protective Action Criteria (PAC) Chemical Database; AUTHOR=U.S. Department of Energy; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65428efee4b045b9ff7cc432; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://edms3.energy.gov/pac/TeelDocs; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=DOE Protective Action Criteria:15514644:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f795487264e47cf3629d9c38f613f124
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =5 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15631282_15631283:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_cfcf674a5f1b5edd3e3392236181e557
ToxValDB_TX_TCEQ 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_TX_TCEQ LOAEL =256.605 mg/m3 Mouse inhalation short-term; 4 days short-term LONG_REF=Zissu, D. 1995. Histopathological changes in the respiratory tract of mice exposed to ten families of airborne chemicals. J Appl Toxicol 15: 207-13; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/68c993f9e4b02565fc7d5b0f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.tceq.texas.gov; SUBSOURCE_URL=https://www.tceq.texas.gov/downloads/toxicology/dsd/final/diisopropylamine.pdf; YEAR=2016; ORIGINAL_YEAR=2016; TOXICOLOGICAL_EFFECT=Histological changes in anterior respiratory epithelium and olfactory epithelium after 4 days of exposure; STUDY_GROUP=TX TCEQ:15954418:M:--; QC_CATEGORY=Manually extracted from unstructured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c488eae632ba4e617451228bb1d63c1b
ToxValDB_TX_TCEQ LOAEL =100 mg/m3 Rat inhalation short-term; 30 days short-term LONG_REF=Roloff, MV and FA Ruecker.1987. One-month rat inhalation study of diisopropylamine. ML-85327; 85107. Monsanto Company, Environmental Health Laboratory. St Louis MO, USA (available from NTIS, Springfield VA, USA; order no NTIS/OTS0513421).; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/68c993f9e4b02565fc7d5b0f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.tceq.texas.gov; SUBSOURCE_URL=https://www.tceq.texas.gov/downloads/toxicology/dsd/final/diisopropylamine.pdf; YEAR=2016; ORIGINAL_YEAR=2016; TOXICOLOGICAL_EFFECT=Corneal lesions, reduced leukocyte counts, and hyperplasia and metaplasia of the nasal turbinates; STUDY_GROUP=TX TCEQ:15954419:M/F:--; QC_CATEGORY=Manually extracted from unstructured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f0e65bdc2a48ecfdadb400331d4b60c8
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier BR9JLI40NO UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15N","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BR9JLI40NO"}
openFDA substances FDA UNII substance identifier BR9JLI40NO UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15N","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BR9JLI40NO"}
openFDA substances FDA UNII substance identifier BR9JLI40NO UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15N","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BR9JLI40NO"}
openFDA substances FDA UNII substance identifier BR9JLI40NO UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H15N","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BR9JLI40NO"}