Is Dihydroxydimethoxychalcone safe in cosmetics?
Dihydroxydimethoxychalcone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Dihydroxydimethoxychalcone
INCI: DIHYDROXYDIMETHOXYCHALCONE
Dihydroxydimethoxychalcone (CAS 131496-17-2 (2',4'-dihydroxy-3,4-dimethoxychalcone, most common cosmetic isomer)) is a cosmetic cosmetic ingredient functioning as Skin-conditioning agent; antioxidant; skin-lightening (tyrosinase inhibition. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
131496-17-2 (2',4'-dihydroxy-3,4-dimethoxychalcone, most common cosmetic isomer)
View industrial chemical safety profile →
Function
Skin-conditioning agent; antioxidant; skin-lightening (tyrosinase inhibition pathway)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted under 21 CFR Parts 700–740; permitted by default
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dihydroxydimethoxychalcone.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Dihydroxydimethoxychalcone.
Regulatory Flags
potential-allergen
natural-origin
Frequently Asked Questions
Is Dihydroxydimethoxychalcone allowed in the EU?
Dihydroxydimethoxychalcone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dihydroxydimethoxychalcone do in cosmetics?
Dihydroxydimethoxychalcone functions as: Skin-conditioning agent; antioxidant; skin-lightening (tyrosinase inhibition pathway). It is classified as a cosmetic ingredient in our database. CAS number: 131496-17-2 (2',4'-dihydroxy-3,4-dimethoxychalcone, most common cosmetic isomer).
Compliance Tools
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