Is Dihydrocholesterol safe in cosmetics?
Dihydrocholesterol has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Dihydrocholesterol
Also known as: Cholestan-3-ol, (3β,5α)-, (3β,5α)-Cholestan-3-ol, 5α-Cholestan-3β-ol, β-Cholestanol, 3β-Hydroxy-5α-cholestane (+10 more)
INCI: DIHYDROCHOLESTEROL
Dihydrocholesterol (CAS 80-97-7) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent, emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 80-97-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent, emollient
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(3S,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey
QYIXCDOBOSTCEI-QCYZZNICSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR reviewed cholesterol class; safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dihydrocholesterol.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Dihydrocholesterol.
Known Synonyms
Cholestan-3-ol, (3β,5α)-
(3β,5α)-Cholestan-3-ol
5α-Cholestan-3β-ol
β-Cholestanol
3β-Hydroxy-5α-cholestane
3β-Hydroxycholestane
5α(H)-Cholestan-3β-ol
5α-Cholestanol
5α-Dihydrocholesterol
Cholestan-3β-ol
Cholestanol
Dihydrocholesterin
Lathostanol
Zymostanol
NSC 18188
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1289436
Frequently Asked Questions
Is Dihydrocholesterol allowed in the EU?
Dihydrocholesterol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dihydrocholesterol do in cosmetics?
Dihydrocholesterol functions as: Skin conditioning agent, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 80-97-7.
Is Dihydrocholesterol used outside cosmetics?
Dihydrocholesterol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dihydrocholesterol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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