Is Dichloro-m-Xylenol safe in cosmetics?
Dichloro-m-Xylenol has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Dichloro-m-Xylenol
INCI: DICHLORO-M-XYLENOL
Dichloro-m-Xylenol (CAS 133-53-9) is a cosmetic cosmetic ingredient functioning as Antimicrobial / preservative. EU Regulation 1223/2009 status: restricted, max 0.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 133-53-9 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial / preservative
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,4-dichloro-3,5-dimethylphenol
InChIKey
IYOLBFFHPZOQGW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.5%
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; not on FDA prohibited list
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dichloro-m-Xylenol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Dichloro-m-Xylenol.
Regulatory Flags
preservative
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DICHLOROXYLENOL
ChEMBL ID
CHEMBL2104302
Max Phase
2
Frequently Asked Questions
Is Dichloro-m-Xylenol allowed in the EU?
Dichloro-m-Xylenol EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dichloro-m-Xylenol do in cosmetics?
Dichloro-m-Xylenol functions as: Antimicrobial / preservative. It is classified as a cosmetic ingredient in our database. CAS number: 133-53-9.
Is Dichloro-m-Xylenol used outside cosmetics?
Dichloro-m-Xylenol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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