Is Diammonium EDTA safe in cosmetics?
Diammonium EDTA has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Diammonium EDTA
Also known as: Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, diammonium salt, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, ammonium salt (1:2), Acetic acid, (ethylenedinitrilo)tetra-, diammonium salt, Diammonium ethylenediaminetetraacetate, Diammonium ethylenediaminetetraacetic acid (+11 more)
INCI: DIAMMONIUM EDTA
Diammonium EDTA (CAS 20824-56-0) is a cosmetic cosmetic ingredient functioning as Chelating agent. NOAEL 500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 20824-56-0 →
Auto-generated CPSR Part A draft with source citations
Function
Chelating agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
azane;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
InChIKey
KYQODXQIAJFKPH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted. CIR reviewed EDTA salts and concluded safe as used.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diammonium EDTA.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Diammonium EDTA across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Chelating agent
Expert Verdict
Expert safety assessment and concern-level summary for Diammonium EDTA.
Known Synonyms
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, diammonium salt
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, ammonium salt (1:2)
Acetic acid, (ethylenedinitrilo)tetra-, diammonium salt
Diammonium ethylenediaminetetraacetate
Diammonium ethylenediaminetetraacetic acid
Dissolvine AM 2-45
EDTA diammonium salt
Ethylenediaminetetraacetic acid diammonium salt
Trilon BAD
Dihydrogenoethylenediaminetetraacetate de diammonium
diammonium dihydrogen ethylenediaminetetraacetate
Diammoniumdihydrogenethylendiamintetraacetat
dihidrogenoetilendiaminatetraacetato de diamonio
N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine] diammonium salt
GLYCINE, N,N'-1,2-ETHANEDIYLBIS[N-CARBOXYMETHYL]-,DIAMMONIUM
EINECS 244-063-4
Chemical Function
Antioxidant
Chelating agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
inert_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Diammonium EDTA allowed in the EU?
Diammonium EDTA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diammonium EDTA do in cosmetics?
Diammonium EDTA functions as: Chelating agent. It is classified as a cosmetic ingredient in our database. CAS number: 20824-56-0.
Is Diammonium EDTA used outside cosmetics?
Diammonium EDTA also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Diammonium EDTA compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Good
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Not Reported
DIBROMOCYANOACETAMIDE
Good
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Antimicrobial
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