Good Cosmetic Ingredient NOAEL Data Sensitization Data

Decylene Glycol

INCI: DECYLENE GLYCOL

Decylene Glycol (CAS 1119-86-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning, antimicrobial/preservative booster, emollient, penetration. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 1119-86-4 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, antimicrobial/preservative booster, emollient, penetration enhancer
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C10H22O2
MW
174.28 g/mol
EC Number
214-288-2
PubChem CID
79141
IUPAC Name
decane-1,2-diol
InChIKey
YSRSBDQINUMTIF-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No specific FDA restrictions; not a sunscreen active

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Decylene Glycol.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Decylene Glycol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =100 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID
NOAEL =1000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Decylene Glycol across SCCS product categories, with measured dermal absorption where available.

Sensitization Profile

Contact sensitization data for Decylene Glycol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
preservative
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: ESSCA; IVDK; NACDG

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

2 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "preservative", "patch_test_frequency_pct": "0.1", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "ESSCA; IVDK; NACDG"}
preservative
{"preservative_class": "Glycol", "antimicrobial_spectrum_bacteria_gp": "Good", "antimicrobial_spectrum_bacteria_gn": "Good", "antimicrobial_spectrum_yeast": "Yes", "antimicrobial_spectrum_mold": "Yes", "mic_staph_aureus_ppm": "2500", "mic_e_coli_ppm": "2500", "mic_pseudomonas_ppm": "2500", "mic_candida_albicans_ppm": "2500", "mic_aspergillus_niger_ppm": "2500", "challenge_test_pass_concentration_p…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance Softener and conditioner
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Decylene Glycol.

Regulatory Flags

ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Decylene Glycol by CAS number or substance name.

Studies
2
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Softener and conditioner Fragrance

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Decylene Glycol safe in cosmetics?

Decylene Glycol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Decylene Glycol allowed in the EU?

Decylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decylene Glycol do in cosmetics?

Decylene Glycol functions as: Skin conditioning, antimicrobial/preservative booster, emollient, penetration enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 1119-86-4.

What is the NOAEL for Decylene Glycol?

The NOAEL (No Observed Adverse Effect Level) for Decylene Glycol is =100 mg/kg bw/day based on a short-term study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Decylene Glycol used outside cosmetics?

Decylene Glycol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Decylene Glycol have different safety status in cosmetics vs industrial chemicals?

Decylene Glycol is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.

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