Is Decursinol safe in cosmetics?
Decursinol has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Decursinol
Also known as: UNII-UBI4YB704B, (+)-Decursinol, 2H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-, 2H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-(+)-, SFE decursinol (+3 more)
INCI: DECURSINOL
Decursinol (CAS 23458-02-8) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin conditioning agent. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 23458-02-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Decursinol is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antioxidant, skin conditioning agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(3S)-3-hydroxy-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-8-one
InChIKey
BGXFQDFSVDZUIW-LBPRGKRZSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not listed in 21 CFR §700.11–700.35 (prohibited/restricted); no CIR final report
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decursinol.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Decursinol.
Known Synonyms
UNII-UBI4YB704B
(+)-Decursinol
2H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-
2H,6H-Benzo(1,2-b:5,4-b')dipyran-2-one, 7,8-dihydro-7-hydroxy-8,8-dimethyl-, (S)-(+)-
SFE decursinol
Smirino
Smyrinol
(S)-(+)-decursinol
Chemical Function
Antioxidant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DECURSINOL
ChEMBL ID
CHEMBL481657
Frequently Asked Questions
Is Decursinol allowed in the EU?
Decursinol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Decursinol do in cosmetics?
Decursinol functions as: Antioxidant, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 23458-02-8.
Is Decursinol used outside cosmetics?
Decursinol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Decursinol have different safety status in cosmetics vs industrial chemicals?
Decursinol is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Compliance Tools
Check Decursinol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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