Is Decapeptide-21 safe in cosmetics?
Decapeptide-21 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Decapeptide-21
INCI: DECAPEPTIDE-21
Decapeptide-21 (CAS Not stated in COSING‑style listing for Palmitoyl Decapeptide‑21; Decapeptide‑21 CAS not widely published) is a cosmetic cosmetic ingredient functioning as Cosmetic peptide ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not stated in COSING‑style listing for Palmitoyl Decapeptide‑21; Decapeptide‑21 CAS not widely published
View industrial chemical safety profile →
Function
Cosmetic peptide ingredient
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as cosmetic ingredient; lipopeptide derivatives marketed for anti-ageing; subject to general FDA cosmetic safety rules
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decapeptide-21.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
peptide
{"trade_name": "Decapeptide 21", "peptide_sequence_amino_acids": "Tyr-Lys-Ser-Lys-His-Tyr-Ser-Ser-Trp-Phe", "peptide_length_residues": "10", "molecular_weight_daltons": "1215", "peptide_class": "enzyme_inhibitor", "mechanism_of_action": "Tyrosinase inhibition and skin brightening", "target_protein_or_receptor": "Tyrosinase/MC1R", "collagen_boost_pct_in_vitro": "0", "elastin_stimulation": "moderate…
Expert Verdict
Expert safety assessment and concern-level summary for Decapeptide-21.
Frequently Asked Questions
Is Decapeptide-21 allowed in the EU?
Decapeptide-21 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decapeptide-21 do in cosmetics?
Decapeptide-21 functions as: Cosmetic peptide ingredient. It is classified as a cosmetic ingredient in our database. CAS number: Not stated in COSING‑style listing for Palmitoyl Decapeptide‑21; Decapeptide‑21 CAS not widely published.
Compliance Tools
Check Decapeptide-21 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Decapeptide-21 in Your Products?
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