Is Cyclovirobuxine safe in cosmetics?
Cyclovirobuxine has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Cyclovirobuxine
INCI: CYCLOVIROBUXINE
Cyclovirobuxine (CAS For Cyclovirobuxine D: 860‑79‑7. (Check whether your supplier’s ingredient is this exact alkaloid or a derivative.)) is a cosmetic cosmetic ingredient functioning as Pharmacologically active cardenolide-like alkaloid investigated as a. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
For Cyclovirobuxine D: 860‑79‑7. (Check whether your supplier’s ingredient is this exact alkaloid or a derivative.)
View industrial chemical safety profile →
Function
Pharmacologically active cardenolide-like alkaloid investigated as a cardiovascular drug. Not a standard cosmetic ingredient.
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Investigated as a drug; not recognized as a cosmetic ingredient. Use in cosmetics would present significant regulatory risk and potential misbranding or adulteration concerns.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cyclovirobuxine.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Cyclovirobuxine.
Frequently Asked Questions
Is Cyclovirobuxine allowed in the EU?
Cyclovirobuxine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyclovirobuxine do in cosmetics?
Cyclovirobuxine functions as: Pharmacologically active cardenolide-like alkaloid investigated as a cardiovascular drug. Not a standard cosmetic ingredient.. It is classified as a cosmetic ingredient in our database. CAS number: For Cyclovirobuxine D: 860‑79‑7. (Check whether your supplier’s ingredient is this exact alkaloid or a derivative.).
Compliance Tools
Check Cyclovirobuxine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Cyclovirobuxine in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cyclovirobuxine in your formulation.