Cyclopropylbimatoprost

INCI: CYCLOPROPYLBIMATOPROST

Cyclopropylbimatoprost (CAS 1138395-12-6) is a cosmetic cosmetic ingredient functioning as Eyelash conditioning (prostaglandin analogue derivative of bimatoprost). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 1138395-12-6 →

Auto-generated CPSR Part A draft with source citations
Function
Eyelash conditioning (prostaglandin analogue derivative of bimatoprost)
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C26H37NO4
MW
427.6 g/mol
PubChem CID
42598149
IUPAC Name
(Z)-N-cyclopropyl-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enamide
InChIKey
DOLPNGMQVSAVIX-DVTMXPNUSA-N

Regulatory Status

EU EU Status prohibited
US US Status permitted
US Notes Not specifically prohibited as a cosmetic ingredient, but bimatoprost itself is an FDA-approved drug (Latisse/Lumigan), which raises drug/cosmetic classification concerns if the analogue exerts pharmacological eyelash-growth activity.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cyclopropylbimatoprost.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant

Expert Verdict

Expert safety assessment and concern-level summary for Cyclopropylbimatoprost.

Chemical Function

Antioxidant

Frequently Asked Questions

Is Cyclopropylbimatoprost safe in cosmetics?

Cyclopropylbimatoprost has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.

Is Cyclopropylbimatoprost allowed in the EU?

Cyclopropylbimatoprost EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclopropylbimatoprost do in cosmetics?

Cyclopropylbimatoprost functions as: Eyelash conditioning (prostaglandin analogue derivative of bimatoprost). It is classified as a cosmetic ingredient in our database. CAS number: 1138395-12-6.

Is Cyclopropylbimatoprost in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cyclopropylbimatoprost in your formulation.