Also known as: α-D-galacto-β-D-Mannan, α-D-Galactopyrano-β-D-mannopyranan, Burtonite V-7-E, EINECS 232-536-8, FEMA No. 2537 (+11 more)
INCI: CYAMOPSIS TETRAGONOLOBA GUM
Cyamopsis Tetragonoloba Gum (CAS 9000-30-0) is a cosmetic cosmetic ingredient functioning as Binding; Emulsion Stabilising; Film Forming; Viscosity Controlling. Reported NOAEL =1000 mg/kg body weight in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted; 2 safety opinions reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 9000-30-0 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Cyamopsis Tetragonoloba Gum.
Calculate MoS for your specific formulation with the MoS Calculator.
6 study endpoints found for Cyamopsis Tetragonoloba Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg body weight | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =1000 mg/kg body weight | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =1000 mg/kg body weight | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =1000 mg/kg body weight | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =2500 mg/kg bw/day | - | Rat | chronic/long term toxicity | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| NOAEL | =2500 mg/kg bw/day | - | Rat | chronic/long term toxicity | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio
netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio
3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LD50 | =8100 mg/kg | Mouse | oral | - | ChemIDplus |
| LD50 | =7000 mg/kg | Rabbit | oral | - | ChemIDplus |
| LD50 | =6770 mg/kg | Rat | oral | - | ChemIDplus |
Expert safety assessment and concern-level summary for Cyamopsis Tetragonoloba Gum.
Public NOAEL study rows linked to Cyamopsis Tetragonoloba Gum by CAS number or substance name.
Units vary across source rows: mg/kg bw/day, mg/kg body weight
Same-CAS public records found in pharmaceutical data.
Same-CAS rows from the pharmaceutical spoke database.
Cyamopsis Tetragonoloba Gum has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 6 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Cyamopsis Tetragonoloba Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Cyamopsis Tetragonoloba Gum functions as: Binding; Emulsion Stabilising; Film Forming; Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9000-30-0.
The NOAEL (No Observed Adverse Effect Level) for Cyamopsis Tetragonoloba Gum is =1000 mg/kg body weight based on a developmental toxicity study via oral route in rat. A total of 6 study endpoints are available. Source: CIR_vision_codex.
Cyamopsis Tetragonoloba Gum also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Check Cyamopsis Tetragonoloba Gum compliance across multiple jurisdictions:
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cyamopsis Tetragonoloba Gum in your formulation.