Is Croscarmellose safe in cosmetics?
Croscarmellose has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Croscarmellose
Also known as: Cross carboxymethyl cellulose sodium, Sodium croscarmellose, Primellose, Vivasol, Ac-Di-Sol SD 411NF (+11 more)
INCI: CROSCARMELLOSE SODIUM
Croscarmellose (CAS 74811-65-7) is a cosmetic cosmetic ingredient functioning as Viscosity controlling, absorbent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical and food safety data.
View industrial chemical safety profile for CAS 74811-65-7 →
Auto-generated CPSR Part A draft with source citations
Function
Viscosity controlling, absorbent
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA GRAS as pharmaceutical excipient with NF monograph. Permitted in cosmetics with no specific restrictions.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Croscarmellose.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Filler
Thickening agent
Expert Verdict
Expert safety assessment and concern-level summary for Croscarmellose.
Known Synonyms
Cross carboxymethyl cellulose sodium
Sodium croscarmellose
Primellose
Vivasol
Ac-Di-Sol SD 411NF
Ac-Di-Sol SD 711
Ac-Di-Sol SDW 802NF
AcDiSol
Explocel
Kiccolate
Kiccolate ND 200
Kiccolate ND 2HS
Kiccolate NDHS
ND 2HS
Nymcel ZSX
CROSCARMELLOSE, SODIUM
Chemical Function
Filler
Thickening agent
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
172
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Crosslinked sodium CMC
E Number
E468
Food Category
emulsifier
Frequently Asked Questions
Is Croscarmellose allowed in the EU?
Croscarmellose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Croscarmellose do in cosmetics?
Croscarmellose functions as: Viscosity controlling, absorbent. It is classified as a cosmetic ingredient in our database. CAS number: 74811-65-7.
Is Croscarmellose used outside cosmetics?
Croscarmellose also appears in pharmaceutical and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Croscarmellose compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
3-Hydroxybutyrate/3-Hydroxyhexanoate Copolymer
Excellent
Same category
Film Forming, Viscosity Controlling, ...
3-Hydroxybutyrate/4-Hydroxybutyrate Copolymer
Excellent
Same category
Film forming, viscosity controlling, ...
4-PCA Dimethicone/Bis-Vinyldimethicone Crosspolymer
Excellent
Same category
Film forming, hair conditioning, skin...
Acrylates Crosspolymer-3
Excellent
Same category
Bulking agent, chelating agent, emuls...
Acrylates Crosspolymer-4
Excellent
Same category
Emulsion stabilizer, film former, dis...
Acrylates Crosspolymer-6
Excellent
Same category
Film former, viscosity increasing age...
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
Excellent
Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
Excellent
Similar safety
Antioxidant; tyrosinase inhibitor; me...
CROCIN
Good
Browse nearby
Antioxidant, Colorant
CRYPTOMERIA JAPONICA LEAF OIL
Good
Browse nearby
Fragrance, Perfuming
CUCUMIS MELO FRUIT WATER
Good
Browse nearby
Humectant, Skin Conditioning
Is Croscarmellose in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Croscarmellose in your formulation.