Good Cosmetic Ingredient NOAEL Data GHS Classified

COLLOIDAL SULFUR

Also known as: Aquilite, Caswell No. 812, Colloidal-S, Collokit, Corosul D and S (+15 more)

COLLOIDAL SULFUR (CAS 7704-34-9) is a cosmetic cosmetic ingredient functioning as Antimicrobial. NOAEL 200 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 7704-34-9 →

Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
231-722-6

Regulatory Status

EU EU Status permitted
US US Status Not specifically regulated

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for COLLOIDAL SULFUR. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =400 mg/kg bw/day dermal Rat short-term ToxValDB_ECHA_IUCLID

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the powder may cause inflammation of the nose and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the respiratory tract. This may result in chronic bronchitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for COLLOIDAL SULFUR across SCCS product categories, with measured dermal absorption where available.

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Warning
Pictograms
Harmful / Irritant
Hazard Class and Category
Skin Irrit. 2
Hazard Statements
  • H315 Causes skin irritation

Inserted via ATP: ATP22

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000,000 - 10,000,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

Additional Jurisdictional Restrictions (1)
Jurisdiction Status Max % Product Type
BR restricted 5 (anti-dandruff) / 10 (anti-acne) a) Anti-dandruff: 5%; b) Anti-acne: 10%; external use only

Additional Ingredient Properties

1 property record from structured ingredient metadata.

ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "8.0", "stable_ph_min": "3.5", "stable_ph_max": "9.0", "degrades_above_ph": "10.0", "degrades_below_ph": "3.0", "ph_dependent_function": "Anti-acne sulfur", "formulation_note": "pH affects suspension", "source": "Formulation literature"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Alloying element Anti-dandruff Anti-static agent Binder Biocide Catalyst Chemical reaction regulator Degradant/impurity Hardener No specific technical function
Regulatory List Membership (2)
EU Regulated in Personal Care FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for COLLOIDAL SULFUR.

Regulatory Flags

cosing-sourced eu-permitted preservative needs-enrichment

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to COLLOIDAL SULFUR by CAS number or substance name.

Studies
1
Lowest NOAEL
400 mg/kg bw/day
Highest NOAEL
400 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Aquilite Caswell No. 812 Colloidal-S Collokit Corosul D and S EINECS 231-722-6 EPA Pesticide Chemical Code 077501 Flour sulphur Ground vocle sulfur Kolloidschwefel 95 Kolofog Kolospray Kristex Magnetic 70, 90, and 95 Microflotox Netzschwefel NSC 403664 Polsulkol extra Rc-schwefel extra Sperlox-S

Chemical Function

Biocide Anti-static agent Softener and conditioner Pharmaceutical Anti-dandruff

Regulatory Lists

detected; Europe; Home maintenance - caulk/sealant active_ingredient; Pesticides active_ingredient; agricultural; applied; Pesticides active_ingredient; agricultural; applied; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides

Australian Status

AICIS status: listed

Frequently Asked Questions

Is COLLOIDAL SULFUR safe in cosmetics?

COLLOIDAL SULFUR has a safety rating of "GOOD" in our database. EU status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is COLLOIDAL SULFUR allowed in the EU?

COLLOIDAL SULFUR EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does COLLOIDAL SULFUR do in cosmetics?

COLLOIDAL SULFUR functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 7704-34-9.

What is the NOAEL for COLLOIDAL SULFUR?

The NOAEL (No Observed Adverse Effect Level) for COLLOIDAL SULFUR is =400 mg/kg bw/day based on a short-term study via dermal route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is COLLOIDAL SULFUR used outside cosmetics?

COLLOIDAL SULFUR also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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