Excellent Cosmetic Ingredient NOAEL Data GHS Classified

CI 77713

Also known as: Carbonic acid, magnesium salt (1:1), Magnesium carbonate, Apolda, C.I. 77713, CSC Book Saver (+15 more)

CI 77713 (CAS 546-93-0) is a cosmetic cosmetic ingredient functioning as Colorant (white pigment, opacifier). Reported NOAEL =290 mg/kg body weight/d (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.

View industrial chemical safety profile for CAS 546-93-0 →

Auto-generated CPSR Part A draft with source citations
Function
Colorant (white pigment, opacifier)
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
CMgO3
MW
84.31 g/mol
EC Number
208-915-9
PubChem CID
11029
IUPAC Name
magnesium carbonate
InChIKey
ZLNQQNXFFQJAID-UHFFFAOYSA-L

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted – GRAS as food additive; used as cosmetic ingredient (absorbent, opacifier)

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for CI 77713.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for CI 77713. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =290 mg/kg body weight/d - - NOAEL study CIR_vision_codex
NOAEL =290 mg/kg body weight/d - - NOAEL study CIR_vision_codex
NOAEL =290 mg/kg body weight/d - - NOAEL study CIR_vision_codex
NOAEL =290 mg/kg body weight/d - - NOAEL study CIR_vision_codex
NOAEL =414 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex
NOAEL =414 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex
NOAEL =414 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex
NOAEL =414 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight/d oral rat developmental toxicity CIR_vision_codex

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Hazard Statements
No hazard classification according to GHS criteria
Long-term Exposure Effects
Lungs may be affected by repeated or prolongated exposure to dust particles.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

EPA ToxValDB — Toxicity Values

1 toxicity value from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 >2000 mg/kg Rat oral - ECHA IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
GROUP; SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

1 property record from structured ingredient metadata.

colorant
{"Common_Name": "Magnesium Silicate (talc)", "Chemical_Name": "Hydrated magnesium silicate", "CAS_Number": "14807-96-6", "Colorant_Type": "Natural Mineral", "Approved_Uses": "All cosmetics", "Max_Concentration_%": "No limit", "EU_Status": "Approved", "US_FDA_Status": "Approved", "Notes": "White, soft powder"}

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
ICSC Safety Card
0969
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (2)
JECFA Evaluation
MAGNESIUM CARBONATE | 1965 | NOT LIMITED | NMRS 40/TRS 339-JECFA 9/16 | FAS 67.29/NMRS 40A,B,C-JECFA 9/159
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Absorbent Binder Dye Filler Flame retardant Flow promoter Heat stabilizer Opacifer Processing aids not otherwise specified Stabilizing agent
Regulatory List Membership (3)
EU Regulated in Personal Care EPA Safer Chemical Ingredients List (SCIL) EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for CI 77713.

Regulatory Flags

colorant epa_safer_alternative eu_cosing_listed

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to CI 77713 by CAS number or substance name.

Studies
20
Lowest NOAEL
290
Highest NOAEL
4128

Units vary across source rows: mg/kg body weight/d, mg/kg body weight

CIR_vision_codex

Known Synonyms

Carbonic acid, magnesium salt (1:1) Magnesium carbonate Apolda C.I. 77713 CSC Book Saver CSC Book Saver Spray Carbonate magnesium DCI Light Magnesium Carbonate Destab Frimiz MZ 1 GP 20 (carbonate) Gold Star (carbonate) Kimboshi MA 70 (carbonate) MSL-AM Upsalite TT (carbonate) Magnesite 33 Magnesite MSS Magnesium Carbonate Gold Star

Chemical Function

Absorbent Dye Opacifer Filler Binder pH regulating agent

Regulatory Lists

inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides inert_ingredient; non_food_use; Pesticides drinking_water; Europe; manufacturing; plastic_additive active_ingredient; animal_products; Europe; pharmaceutical; residue Europe; supplements Europe; food_additive; supplements Europe; plastic_additive Europe; Personal care SCIL (9/2019) Canada; pharmaceutical Canada; pharmaceutical

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical and food safety data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
MAGNESIUM CARBONATE
ChEMBL ID
CHEMBL1200736
Max Phase
4
Adverse Event Associations
58
View full pharmaceutical profile →
SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Magnesium carbonate
E Number
E504
ADI
NOT LIMITED mg/kg bw
Food Category
preservative
View full food safety profile →

Frequently Asked Questions

Is CI 77713 safe in cosmetics?

CI 77713 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.

Is CI 77713 allowed in the EU?

CI 77713 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 77713 do in cosmetics?

CI 77713 functions as: Colorant (white pigment, opacifier). It is classified as a cosmetic ingredient in our database. CAS number: 546-93-0.

What is the NOAEL for CI 77713?

The NOAEL (No Observed Adverse Effect Level) for CI 77713 is =290 mg/kg body weight/d based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.

Is CI 77713 used outside cosmetics?

CI 77713 also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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