Is CI 74100 safe in cosmetics?
CI 74100 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: prohibited.
Moderate
Cosmetic Ingredient
CI 74100
Also known as: C.I. Pigment Blue 16, Fastogen Blue 8110, Fastogen Blue 8120, Fastogen Blue 8120B, Fastogen Blue 8120BS (+15 more)
CI 74100 (CAS 574-93-6) is a cosmetic cosmetic ingredient functioning as Colorant (blue pigment). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 574-93-6 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant (blue pigment)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,11,20,29,37,38,39,40-octazanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-1,3,5,7,9,11,13,15,17,19(39),20,22,24,26,28,30(37),31,33,35-nonadecaene
InChIKey
IEQIEDJGQAUEQZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Not listed as an FDA-approved color additive for cosmetics under 21 CFR Parts 73, 74, or 82
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 74100.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Blue
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
Product type: Rinse-off products.
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Pigment
Surface modifier
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for CI 74100.
Regulatory Flags
colorant
Known Synonyms
C.I. Pigment Blue 16
Fastogen Blue 8110
Fastogen Blue 8120
Fastogen Blue 8120B
Fastogen Blue 8120BS
Fastogen Blue 8130
Heliogen Blue D 7490
Heliogen Blue D 7560
Heliogen Blue D 7565
Heliogen Blue L 7460
Heliogen Blue L 7560
Heliogen Blue LG
Irgalite Blue GLS
Irgalite GLVO
Monastral Fast Blue G
Vulcafor Fast Blue G
Vulcanosine Fast Bremen Blue G
Vynamon Blue G
CI Pigment Blue 16
5,28:14,19-Diimino-7,12:26,21-dinitrilotetrabenzo(c,h,m,r)(1,6,11,16)tetraazacycloeicosine
Chemical Function
Dye
Surface modifier
Pigment
Regulatory Lists
Europe; plastic_additive
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
Europe; Other direct contact consumer goods; residue
Arts and crafts/Office supplies - body paint - tattoo ink; Europe
Canada; pharmaceutical
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
Europe; Other direct contact consumer goods; residue
Arts and crafts/Office supplies - body paint - tattoo ink; Europe
Canada; pharmaceutical
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe
Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CIAFTALAN
ChEMBL ID
CHEMBL262101
Max Phase
1
Frequently Asked Questions
Is CI 74100 allowed in the EU?
CI 74100 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 74100 do in cosmetics?
CI 74100 functions as: Colorant (blue pigment). It is classified as a cosmetic ingredient in our database. CAS number: 574-93-6.
Is CI 74100 used outside cosmetics?
CI 74100 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 74100 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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