Is CI 26100 safe in cosmetics?
CI 26100 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
CI 26100
Also known as: C.I. 26100, 1-[2-[4-(2-Phenyldiazenyl)phenyl]diazenyl]-2-naphthalenol, 1-(p-Phenylazophenylazo)-2-naphthol (Sudan III), 111440 Red, DC Red 17 (+15 more)
CI 26100 (CAS 85-86-9) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 85-86-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
CI 26100 is classified GHS Danger (H351, H315, H317, H318, H335, H341, H412) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1-[(4-phenyldiazenylphenyl)diazenyl]naphthalen-2-ol
InChIKey
FHNINJWBTRXEBC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
D&C Red No. 17; permitted for externally applied cosmetics and drugs per 21 CFR; not permitted for eye area or lip products
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 26100.
Calculate MoS for your specific formulation with the MoS Calculator.
IARC Carcinogenicity
International Agency for Research on Cancer (WHO) monograph evaluation.
IARC Group
3
Volume
8, Sup 7
Evaluation Year
1987
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1353
(EC) 2013/344
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1353
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
India: Permitted Colorant
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | permitted_colorant | - | Not eye area; skin only |
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Aggregated DA Values (1 records across 5 sources)
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured | 36.1% | in_vitro | - | SCCP/0013 |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
Sudan III | Group 3: Not classifiable as to its carcinogenicity to humans | Volume 8: (1975) Some Aromatic Azo Compounds | Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)
Source: International Agency for Research on Cancer (IARC)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Fragrance
Regulatory List Membership (4)
EU Banned in Cosmetics
EU Regulated in Personal Care
IFRA Fragrance Transparency List
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 26100.
Regulatory Flags
azo-dye
solvent-dye
eu-annex-iv-restricted
fda-dc-red-17
external-use-only
no-eye-no-lip
sensitization-concern
sudan-impurity
eu_banned_cosmetics
ifra_fragrance
eu_cosing_listed
Dermal Absorption
View details ->| Absorption % | Method | Vehicle |
|---|---|---|
| 36.1% | in_vitro | - |
Known Synonyms
C.I. 26100
1-[2-[4-(2-Phenyldiazenyl)phenyl]diazenyl]-2-naphthalenol
1-(p-Phenylazophenylazo)-2-naphthol (Sudan III)
111440 Red
DC Red 17
Japan Red No. 225
Oil Red 3G
Oil Red Extra
Red 17
Red Zh
Sudan 3
VisioTag
1-(4-(phenylazo)phenylazo)-2-naphthol
EC No.: 201-638-4
EINECS 201-638-4
Fat Red RS
D & C Red No. 17
4-16-00-00248
Atul Oil Red G
Benzeneazobenzeneazo-beta-naphthol
Chemical Function
Dye
Fragrance
Regulatory Lists
banned; Europe; Personal care
Europe; Personal care
IFRA Transparency
inert_ingredient; non_food_use; Pesticides
pharmaceutical
Personal care
Medical/dental
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL2001927
Frequently Asked Questions
Is CI 26100 allowed in the EU?
CI 26100 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 26100 do in cosmetics?
CI 26100 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 85-86-9.
Is CI 26100 used outside cosmetics?
CI 26100 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does CI 26100 have different safety status in cosmetics vs industrial chemicals?
CI 26100 is classified GHS Danger (H351, H315, H317, H318, H335, H341, H412) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check CI 26100 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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