Is CI 12370 (Pigment Red 112 / Permanent Red FGR) safe in cosmetics?
CI 12370 (Pigment Red 112 / Permanent Red FGR) has a safety rating of "MODERATE" in our database. EU status: restricted. US status: prohibited.
Moderate
Cosmetic Ingredient
CI 12370 (Pigment Red 112 / Permanent Red FGR)
Also known as: 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-, 3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide, 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-, EINECS 229-440-3, UNII-6S30UYY7FD
INCI: CI 12370
CI 12370 (Pigment Red 112 / Permanent Red FGR) (CAS 6535-46-2) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 6535-46-2 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
3-hydroxy-N-(2-methylphenyl)-4-[(2,4,5-trichlorophenyl)diazenyl]naphthalene-2-carboxamide
InChIKey
JQNJCQYNSLCFAC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
prohibited
US Notes
Not listed on FDA-approved color additives list (21 CFR Parts 73/74/82). CI 12370 has no certifiable equivalent in the US and appears in FDA Import Alert 53-06 as non-permitted. Cannot legally be used in cosmetics marketed in the United States.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 12370 (Pigment Red 112 / Permanent Red FGR).
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1346
(EC) 2013/344
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1346
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Pigment
Regulatory List Membership (3)
EU Banned in Cosmetics
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 12370 (Pigment Red 112 / Permanent Red FGR).
Regulatory Flags
eu-annex-iv-rinse-off-only
not-fda-approved
fda-import-alert-53-06
hair-dye-prohibited-eu
azo-dye
chlorinated-azo
aromatic-amine-precursor
no-leave-on-eu
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-
3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide
2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-
EINECS 229-440-3
UNII-6S30UYY7FD
Chemical Function
Dye
Pigment
Regulatory Lists
Europe; Personal care
banned; Europe; Personal care
Europe; plastic_additive
Europe; Toys and children's products
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 12370 (Pigment Red 112 / Permanent Red FGR) allowed in the EU?
CI 12370 (Pigment Red 112 / Permanent Red FGR) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 12370 (Pigment Red 112 / Permanent Red FGR) do in cosmetics?
CI 12370 (Pigment Red 112 / Permanent Red FGR) functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 6535-46-2.
Is CI 12370 (Pigment Red 112 / Permanent Red FGR) used outside cosmetics?
CI 12370 (Pigment Red 112 / Permanent Red FGR) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 12370 (Pigment Red 112 / Permanent Red FGR) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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