Is Cetoleth-25 safe in cosmetics?
Cetoleth-25 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Cetoleth-25
Also known as: Alcohols, C16-18 and C18-unsaturated, ethoxylated, Cemulsol 285, Cetyloleyl alcohol ethoxylate, Simulsol C, Rhodasurf CET 5 (+15 more)
INCI: CETOLETH-25
Cetoleth-25 (CAS 68920-66-1) is a cosmetic cosmetic ingredient functioning as Surfactant — emulsifying, cleansing. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68920-66-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Cetoleth-25 is classified GHS Danger (H302, H315, H318, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Surfactant — emulsifying, cleansing
Safety Rating
MODERATE
Chemistry & Identifiers
EC Number
500-236-9
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; has reported cosmetic use per CIR data profile
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cetoleth-25.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Cetoleth-25 across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Dispersing agent
Emulsifier
Lubricating agent
Solvent
Surfactant (surface active agent)
Thickening agent
Wetting agent (non-aqueous)
Expert Verdict
Expert safety assessment and concern-level summary for Cetoleth-25.
Known Synonyms
Alcohols, C16-18 and C18-unsaturated, ethoxylated
Cemulsol 285
Cetyloleyl alcohol ethoxylate
Simulsol C
Rhodasurf CET 5
Cimagal-O
Empilan KL 6
Alcools en C16-18 et en C18 insatures, ethoxyles
SDA 11-065-00
Alcohols, C16-18(even numbered) and C18 unsaturated, ethoxylated < 2.5 EO
Rhodasurf CET 2
Unsatd. (C=18) and (C=16-18) ethoxylated alcohols
Remcopal OC 9
Alcohols C16-18,18 unsaturated,ethoxylated
Emulmin 110
Remcopal OC 5
Emulsogen M
Remcopal OC 23
Emulsogen M-A
Remcopal 220
Chemical Function
Surfactant (surface active agent)
Cleaning agent
Thickening agent
Regulatory Lists
Cleaning products and household care - shoes; Europe
Cleaning products and household care - shoes; Europe
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cetoleth-25 allowed in the EU?
Cetoleth-25 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cetoleth-25 do in cosmetics?
Cetoleth-25 functions as: Surfactant — emulsifying, cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68920-66-1.
Is Cetoleth-25 used outside cosmetics?
Cetoleth-25 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Cetoleth-25 have different safety status in cosmetics vs industrial chemicals?
Cetoleth-25 is classified GHS Danger (H302, H315, H318, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Cetoleth-25 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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