Is Calcium Monofluorophosphate safe in cosmetics?
Calcium Monofluorophosphate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Calcium Monofluorophosphate
INCI: CALCIUM MONOFLUOROPHOSPHATE
Calcium Monofluorophosphate (CAS 7789-74-4) is a cosmetic cosmetic ingredient functioning as Antiplaque agent (oral care). EU Regulation 1223/2009 status: restricted, max 0.15%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 7789-74-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Calcium Monofluorophosphate is classified GHS Danger (H302, H312, H332, H314, H315, H318, H319, H335) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antiplaque agent (oral care)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
calcium fluoro-dioxido-oxo-lambda5-phosphane
InChIKey
GFIKIVSYJDVOOZ-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.15%
US US Status
permitted
US Notes
Adequate at permitted concentrations — well-established fluoride toxicology; acute toxicity concern only at gross over-ingestion
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Monofluorophosphate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Oral products. Max: 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 %.
BRIN Brazil/India Cosmetics
India: Restricted · max 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 %
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Pharmaceutical
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Monofluorophosphate.
Regulatory Flags
eu_cosing_listed
Chemical Function
Pharmaceutical
Regulatory Lists
Europe; Personal care; restricted
Frequently Asked Questions
Is Calcium Monofluorophosphate allowed in the EU?
Calcium Monofluorophosphate EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Monofluorophosphate do in cosmetics?
Calcium Monofluorophosphate functions as: Antiplaque agent (oral care). It is classified as a cosmetic ingredient in our database. CAS number: 7789-74-4.
Is Calcium Monofluorophosphate used outside cosmetics?
Calcium Monofluorophosphate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Calcium Monofluorophosphate have different safety status in cosmetics vs industrial chemicals?
Calcium Monofluorophosphate is classified GHS Danger (H302, H312, H332, H314, H315, H318, H319, H335) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Compliance Tools
Check Calcium Monofluorophosphate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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