Is C18-36 Acid Glycol Ester safe in cosmetics?
C18-36 Acid Glycol Ester has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
C18-36 Acid Glycol Ester
INCI: C18-36 ACID GLYCOL ESTER
C18-36 Acid Glycol Ester (CAS 94944-95-3) is a cosmetic cosmetic ingredient functioning as Emollient, emulsifying agent, skin conditioning agent, surfactant; forms stable. NOAEL 150 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 94944-95-3 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, emulsifying agent, skin conditioning agent, surfactant; forms stable oil-in-water emulsions, increases viscosity, softens and smoothes skin
Safety Rating
GOOD
Chemistry & Identifiers
EC Number
305-673-7
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not independently regulated by FDA; used as cosmetic ingredient under general cosmetic regulations; GRAS-analogous fatty acid ester
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for C18-36 Acid Glycol Ester.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for C18-36 Acid Glycol Ester. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for C18-36 Acid Glycol Ester across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Softener and conditioner
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for C18-36 Acid Glycol Ester.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to C18-36 Acid Glycol Ester by CAS number or substance name.
Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Chemical Function
Surfactant (surface active agent)
Softener and conditioner
Emulsifier
Australian Status
AICIS status: listed
Frequently Asked Questions
Is C18-36 Acid Glycol Ester allowed in the EU?
C18-36 Acid Glycol Ester EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does C18-36 Acid Glycol Ester do in cosmetics?
C18-36 Acid Glycol Ester functions as: Emollient, emulsifying agent, skin conditioning agent, surfactant; forms stable oil-in-water emulsions, increases viscosity, softens and smoothes skin. It is classified as a cosmetic ingredient in our database. CAS number: 94944-95-3.
What is the NOAEL for C18-36 Acid Glycol Ester?
The NOAEL (No Observed Adverse Effect Level) for C18-36 Acid Glycol Ester is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is C18-36 Acid Glycol Ester used outside cosmetics?
C18-36 Acid Glycol Ester also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check C18-36 Acid Glycol Ester compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
Excellent
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
Excellent
Same category
Skin conditioning (emollient)
Acetyl Ornithine
Excellent
Same category
Emollient
Acetyl Proline
Excellent
Same category
Emollient
Acetyl Triethylhexyl Citrate
Excellent
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
Excellent
Same category
Plasticiser, Skin Conditioning (Emoll...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
Good
Similar safety
Humectant, Skin Conditioning - Humect...
Salmo Ovum Extract
Good
Chemical family
Skin conditioning agent
Salmon Egg Extract
Good
Chemical family
Skin conditioning agent
C18-20 Glycol Isostearate
Good
Browse nearby
Skin conditioning; skin conditioning ...
Is C18-36 Acid Glycol Ester in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for C18-36 Acid Glycol Ester in your formulation.