NOAEL Studies
Cosmetic Ingredient
C12-14 Pareth-12 NOAEL Studies
INCI: C12-14 PARETH-12
CAS: 68439-50-9
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
NTP_ICE_acute_oral 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | LD50 | >2000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_9378; row=1381; data_type=In Vivo; mixture=Chemical; chemical_name=Alcohols, C12-14, ethoxylated; preferred_name=Alcohols, C12-14, ethoxylated; dtxsid=DTXSID0041931; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID0041931; source_file=acute_oral.xlsx |
ToxValDB_ECHA_IUCLID 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LOAEL | =200 | mg/kg bw/day | Rabbit | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac56e4b0a7c65d1be9b0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/16040?documentUUID=93147e7c-f030-4fcf-a45f-4ef0c0bce6c3; YEAR=2000; ORIGINAL_YEAR=2000; TOXICOLOGICAL_EFFECT=maternal: clinical signs|maternal: early or late resorptions; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs|reproduction; STUDY_GROUP=ECHA IUCLID:15823358:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_11e46194107527235d8742dc01978df4 |
| ToxValDB_ECHA_IUCLID | NOAEL | =200 | mg/kg bw/day | Rabbit | oral | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac56e4b0a7c65d1be9b0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/16040?documentUUID=93147e7c-f030-4fcf-a45f-4ef0c0bce6c3; YEAR=2000; ORIGINAL_YEAR=2000; STUDY_GROUP=ECHA IUCLID:15823455:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_d3a5f80631006e3c69ca2ac526b669a9 |
| ToxValDB_ECHA_IUCLID | NOAEL | >=1000 | mg/kg bw/day | Rat | oral | subchronic (developmental); 56 days | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaeb1e4b0a7c65d1ca7fe; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/16040?documentUUID=93147e7c-f030-4fcf-a45f-4ef0c0bce6c3; YEAR=2000; ORIGINAL_YEAR=2000; STUDY_GROUP=ECHA IUCLID:15848893:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_a2b8fb02416d10f126103e11c5962ffd |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =19.6 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629531:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_39ea9d5514dda665af92d7b0e03b6788 |
openFDA substances 20 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 302740L8OX | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"302740L8OX"} |
| openFDA substances | FDA UNII substance identifier | 93RY22U87E | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"93RY22U87E"} |
| openFDA substances | FDA UNII substance identifier | G4H4YP2VNC | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"G4H4YP2VNC"} |
| openFDA substances | FDA UNII substance identifier | R66I1M1LNH | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"R66I1M1LNH"} |
| openFDA substances | FDA UNII substance identifier | M0LJS773XW | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"M0LJS773XW"} |
| openFDA substances | FDA UNII substance identifier | 302740L8OX | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"302740L8OX"} |
| openFDA substances | FDA UNII substance identifier | 302740L8OX | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"302740L8OX"} |
| openFDA substances | FDA UNII substance identifier | 93RY22U87E | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"93RY22U87E"} |
| openFDA substances | FDA UNII substance identifier | 93RY22U87E | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"93RY22U87E"} |
| openFDA substances | FDA UNII substance identifier | G4H4YP2VNC | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"G4H4YP2VNC"} |
| openFDA substances | FDA UNII substance identifier | G4H4YP2VNC | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"G4H4YP2VNC"} |
| openFDA substances | FDA UNII substance identifier | R66I1M1LNH | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"R66I1M1LNH"} |
| openFDA substances | FDA UNII substance identifier | R66I1M1LNH | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"R66I1M1LNH"} |
| openFDA substances | FDA UNII substance identifier | 302740L8OX | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"302740L8OX"} |
| openFDA substances | FDA UNII substance identifier | M0LJS773XW | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"M0LJS773XW"} |
| openFDA substances | FDA UNII substance identifier | M0LJS773XW | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"M0LJS773XW"} |
| openFDA substances | FDA UNII substance identifier | 93RY22U87E | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"93RY22U87E"} |
| openFDA substances | FDA UNII substance identifier | G4H4YP2VNC | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"G4H4YP2VNC"} |
| openFDA substances | FDA UNII substance identifier | R66I1M1LNH | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"R66I1M1LNH"} |
| openFDA substances | FDA UNII substance identifier | M0LJS773XW | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"M0LJS773XW"} |