Is Bryonolic Acid safe in cosmetics?
Bryonolic Acid has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Bryonolic Acid
Also known as: D:C-Friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-, (2S-(2alpha,4aalpha,6aalpha,8abeta,10alpha,12aalpha,14abeta,14balpha))-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-Eicosahydro-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-2-picenecarboxylic acid, 3beta-Hydroxy-D-C-friedoolean-8-en-29-oic acid, UNII-J7YR6A878I
INCI: BRYONOLIC ACID
Bryonolic Acid (CAS 24480-45-3) is a cosmetic cosmetic ingredient functioning as Skin Conditioning (anti-inflammatory, antioxidant). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 24480-45-3 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning (anti-inflammatory, antioxidant)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2S,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,3,4,5,6,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-2-carboxylic acid
InChIKey
BHVJSLPLFOAMEV-UHIFYLTQSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not established — No published NOAEL, SED, or dermal absorption study for cosmetic exposure calculation
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bryonolic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Bryonolic Acid.
Known Synonyms
D:C-Friedoolean-8-en-29-oic acid, 3-hydroxy-, (3beta,20beta)-
(2S-(2alpha,4aalpha,6aalpha,8abeta,10alpha,12aalpha,14abeta,14balpha))-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-Eicosahydro-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-2-picenecarboxylic acid
3beta-Hydroxy-D-C-friedoolean-8-en-29-oic acid
UNII-J7YR6A878I
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Bryonolic Acid allowed in the EU?
Bryonolic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bryonolic Acid do in cosmetics?
Bryonolic Acid functions as: Skin Conditioning (anti-inflammatory, antioxidant). It is classified as a cosmetic ingredient in our database. CAS number: 24480-45-3.
Compliance Tools
Check Bryonolic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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