Is Bis-Aminopropyl Dimethicone safe in cosmetics?
Bis-Aminopropyl Dimethicone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Bis-Aminopropyl Dimethicone
Also known as: Poly(dimethylsiloxane), bis(3-aminopropyl) terminated, POLYDIMETHYLSILOXANE, DIAMINOPROPYL
INCI: BIS-AMINOPROPYL DIMETHICONE
Bis-Aminopropyl Dimethicone (CAS 106214-84-0) is a cosmetic cosmetic ingredient functioning as Hair conditioning agent, hair fixing agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 106214-84-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Bis-Aminopropyl Dimethicone is classified GHS Danger (H315, H318, H319, H335, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Hair conditioning agent, hair fixing agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-[[[3-aminopropyl(dimethyl)silyl]oxy-dimethylsilyl]oxy-dimethylsilyl]propan-1-amine
InChIKey
ZWRBLCDTKAWRHT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR safe as used (2003, reaffirmed 2022). Highest reported use approximately 0.05% in rinsing products.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bis-Aminopropyl Dimethicone.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
8 property records from structured ingredient metadata.
baby_pediatric
{"cas_number": "113063-45-5", "ingredient_class": "other", "pediatric_safety_rating": "acceptable", "minimum_age_months": "24", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Cationic silicone", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Non-absorbed polymer", "skin_surface_area_to_weight…
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "1200+", "bioaccumulative": "yes", "aquatic_toxicity_level": "low", "coral_reef_safe": "unknown", "marine_toxicity": "low toxicity", "freshwater_toxicity": "very persistent", "soil_toxicity": "accumulates", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restri…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "medium/coarse", "curl_pattern_suitability": "curly/coily", "porosity_suitability": "high", "protein_sensitivity": "protein", "moisture_protein_balance": "modified-cg", "cg_method_approved": "non-water-soluble", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "yes", "heat_protectant": "yes",…
hair_conditioning
{"cas_number": "106842-44-8", "ingredient_class": "silicone_conditioner", "chemical_type": "amino_silicone", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "yes", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic_film_forming", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "amino_functional_high_substantivity", "wet_combing_…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "9.0", "stable_ph_min": "3.5", "stable_ph_max": "10.0", "ph_dependent_function": "Amino-functional silicone", "formulation_note": "Hair conditioning", "source": "Formulation literature"}
polymer
{"cas_number": "106842-44-8", "ingredient_class": "conditioning/detangling", "polymer_type": "silicone_based", "chemical_backbone": "other", "molecular_weight_Da_range": "4000-32000", "ionic_character": "cationic", "charge_density_meq_g": "0.8-1.8", "pH_viscosity_sensitivity": "moderate", "salt_tolerance": "moderate", "electrolyte_effect_on_viscosity": "moderate", "temperature_viscosity_sensitivit…
silicone
{"cas_number": "106842-44-8", "silicone_class": "amodimethicone", "molecular_weight_Da": "6200.0", "viscosity_cSt": "1500", "volatility": "non_volatile", "evaporation_rate_relative_to_D5": "0.008", "refractive_index": "1.4045", "specific_gravity": "0.978", "flash_point_C": "105.0", "surface_tension_mN_m": "21.8", "spreading_coefficient": "3.9", "film_forming_ability": "excellent", "skin_feel": "ve…
solubility_hlb
{"water_soluble": "partial", "oil_soluble": "yes", "soluble_in": "silicones, water, ethanol", "insoluble_in": "oils", "log_p": "3.2", "appearance": "clear liquid", "source": "Dow"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Bis-Aminopropyl Dimethicone.
Known Synonyms
Poly(dimethylsiloxane), bis(3-aminopropyl) terminated
POLYDIMETHYLSILOXANE, DIAMINOPROPYL
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Bis-Aminopropyl Dimethicone allowed in the EU?
Bis-Aminopropyl Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bis-Aminopropyl Dimethicone do in cosmetics?
Bis-Aminopropyl Dimethicone functions as: Hair conditioning agent, hair fixing agent. It is classified as a cosmetic ingredient in our database. CAS number: 106214-84-0.
Is Bis-Aminopropyl Dimethicone used outside cosmetics?
Bis-Aminopropyl Dimethicone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Bis-Aminopropyl Dimethicone have different safety status in cosmetics vs industrial chemicals?
Bis-Aminopropyl Dimethicone is classified GHS Danger (H315, H318, H319, H335, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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