Is Bioresmethrin safe in cosmetics?
Bioresmethrin has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Bioresmethrin
Also known as: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R,3R)-, 3-Furanmethanol, 5-benzyl-, 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate, trans-(+)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R,3R)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R-trans)-, Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-,(5-benzyl-3-furyl)methyl ester, trans-(+)- (+15 more)
INCI: BIORESMETHRIN
Bioresmethrin (CAS 28434-01-7) is a cosmetic cosmetic ingredient functioning as Insecticide (pyrethroid pesticide - not a cosmetic function). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 28434-01-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Bioresmethrin is prohibited in EU cosmetics but has active industrial GHS classifications (H227, H302, H336, H341, H360, H410, H400).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Insecticide (pyrethroid pesticide - not a cosmetic function)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
cis-(5-benzylfuran-3-yl)methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
InChIKey
VEMKTZHHVJILDY-UXHICEINSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not permitted in cosmetics - classified as a pesticide under EPA regulation; no cosmetic use authorization
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bioresmethrin.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Warning
Pictograms
Environmental Hazard
Hazard Class and Category
Aquatic Acute 1; Aquatic Chronic 1
Hazard Statements
- H400 Very toxic to aquatic life
- H410 Very toxic to aquatic life with long lasting effects
Specific Concentration Limits / M-factors
M = 1000
Inserted via ATP: ATP01corr
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
ICSC Safety Card
0229
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Expert Verdict
Expert safety assessment and concern-level summary for Bioresmethrin.
Known Synonyms
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R,3R)-
3-Furanmethanol, 5-benzyl-, 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate, trans-(+)-
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R,3R)-
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-,[5-(phenylmethyl)-3-furanyl]methyl ester, (1R-trans)-
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-,(5-benzyl-3-furyl)methyl ester, trans-(+)-
(+)-trans-Bioresmethrin
(+)-trans-Resmethrin
1R-trans-Resemethrin
5-Benzyl-3-furylmethyl (+)-trans-chrysanthemate
AI 3-27662
d-trans-(5-Benzyl-3-furyl)methyl chrysanthemate
d-trans-Chrysron
d-trans-Resmethrin
d-trans-[(5-Benzyl-3-furyl)methyl] chrysanthemumate
FMC 18739
Isathrine
Isatrin
NIA 18739
NRDC 107
Penick 1390
Regulatory Lists
active_ingredient; Europe; Pesticides
active_ingredient; Australia
pharmaceutical
active_ingredient; Europe; Pesticides
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BIORESMETHRIN
ChEMBL ID
CHEMBL2106605
Max Phase
2
Frequently Asked Questions
Is Bioresmethrin allowed in the EU?
Bioresmethrin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Bioresmethrin do in cosmetics?
Bioresmethrin functions as: Insecticide (pyrethroid pesticide - not a cosmetic function). It is classified as a cosmetic ingredient in our database. CAS number: 28434-01-7.
Is Bioresmethrin used outside cosmetics?
Bioresmethrin also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Bioresmethrin have different safety status in cosmetics vs industrial chemicals?
Bioresmethrin is prohibited in EU cosmetics but has active industrial GHS classifications (H227, H302, H336, H341, H360, H410, H400).
Compliance Tools
Check Bioresmethrin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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