NOAEL Studies Cosmetic Ingredient

Barium Chloride NOAEL Studies

INCI: BARIUM CHLORIDE

CAS: 10361-37-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB DOE Wildlife Benchmarks 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB DOE Wildlife Benchmarks NOAEL =5.1 mg/kg bw/day Rat oral - repeat dose other STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65bd1d53e4b063812d68c240; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://rais.ornl.gov/documents/tm86r3.pdf; STUDY_GROUP=DOE Wildlife Benchmarks:15511550:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b063ea2dae97f47c580e81f63f77adeb
ECHA 9 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA NOAEL =38 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eacb3e4b0a7c65d1c06c0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/6/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850253_15850254_15850255:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_1dd72b636881eca9e9c31cf9d5333627
ECHA NOAEL =38.1 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae65e4b0a7c65d1c9008; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/24153/7/6/2?documentUUID=f4c598b6-c61a-429c-897b-9b855dff173a; YEAR=1978; ORIGINAL_YEAR=1978; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850256_15850257_15850258:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_3ec61fcaa322b05dfd01f0bf4ed19365
ECHA NOAEL =45.7 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae66e4b0a7c65d1c9116; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11875/7/6/2?documentUUID=c504d3a6-707b-4989-8241-f4c8d1063573; YEAR=1977; ORIGINAL_YEAR=1977; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15847233_15847693_15848765:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_082147b5419fbe40c12baf04a4ad9cfe
ECHA NOAEL =61.1 mg/kg bw/day Rat oral chronic; 92 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eacb3e4b0a7c65d1c06c6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/6/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15848312:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_77f7fd065383943635a1fc013597be2a
ECHA NOAEL =80.9 mg/kg bw/day Rat oral chronic; 92 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eacb3e4b0a7c65d1c06c6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/6/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15849051:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_5df132790cddd24f8e990c8726787ca8
ECHA NOAEL =209 mg/kg bw/day Rat oral short-term; 10 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c9f5e4b0a7c65d21f8cd; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/6/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832998_15833994_15844965:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_56b7946676285d0ab5edefa775684a6e
ECHA NOAEL =446 mg/kg bw/day Rat oral chronic; 92 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eacb3e4b0a7c65d1c06c6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/6/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15848419:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_b2c22fa8e4b02725a33a84abb278d861
ECHA NOAEL =2000 ppm Mouse oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c883e4b0a7c65d218f18; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/9/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15857295:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0f6c206ed0c40e5a8edbb141540e07a6
ECHA NOAEL =4000 ppm Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa4ae4b0a7c65d1b5267; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15037/7/9/2?documentUUID=1c00e4bc-dae4-45b9-842d-175c6b5e3fd2; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15855524:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_40a330b77832a374f5450f9d1639cbf0
ToxValDB GESTIS DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL systemic =8.8 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629924:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_fd7452f8d2a372434339707ef783bea6
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0VK51DA1T2 UNII - - - chemical {"approval_status":null,"molecular_formula":"Ba.2Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0VK51DA1T2"}
openFDA substances FDA UNII substance identifier 0VK51DA1T2 UNII - - - chemical {"approval_status":null,"molecular_formula":"Ba.2Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0VK51DA1T2"}
openFDA substances FDA UNII substance identifier 0VK51DA1T2 UNII - - - chemical {"approval_status":null,"molecular_formula":"Ba.2Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0VK51DA1T2"}
openFDA substances FDA UNII substance identifier 0VK51DA1T2 UNII - - - chemical {"approval_status":null,"molecular_formula":"Ba.2Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0VK51DA1T2"}