Is Asparagine safe in cosmetics?
Asparagine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Asparagine
INCI: ASPARAGINE
Asparagine (CAS 70-47-3 (L-Asparagine)) is a cosmetic cosmetic ingredient functioning as Skin conditioning, hair conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 70-47-3 (L-Asparagine) →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, hair conditioning
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA GRAS as food substance (21 CFR 172.320); no specific cosmetic restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Asparagine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
acne
{"cas_number": "70-47-3", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_ac…
anti_aging
{"anti_aging_claim": "hydration-plumping", "mechanism_of_action": "Building block for proteins, NMF component", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "5-10", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Int J Cosmet Sci", "improve…
Expert Verdict
Expert safety assessment and concern-level summary for Asparagine.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Asparagine by CAS number or substance name.
Studies
6
Lowest NOAEL
1650 mg/kg bw/day
Highest NOAEL
1730 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Asparagine allowed in the EU?
Asparagine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Asparagine do in cosmetics?
Asparagine functions as: Skin conditioning, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 70-47-3 (L-Asparagine).
Compliance Tools
Check Asparagine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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