Moderate Cosmetic Ingredient NOAEL Data

Aluminum Lactate

Also known as: Propanoic acid, 2-hydroxy-, aluminum complex, Aluminum, tris(2-hydroxypropanoate-O1,O2)-, Aluminum, tris(2-hydroxypropanoato-O1,O2)-, aluminum tris(alpha-hydroxypropionate), Aluminum, tris(2-(hydroxy-kappaO)propanoato-kappaO)- (+11 more)

INCI: ALUMINUM LACTATE

Aluminum Lactate (CAS 18917-91-4) is a cosmetic cosmetic ingredient functioning as Astringent, buffering agent, antimicrobial. NOAEL 27 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 18917-91-4 →

Auto-generated CPSR Part A draft with source citations
Function
Astringent, buffering agent, antimicrobial
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C9H15AlO9
MW
294.19 g/mol
EC Number
242-670-9
PubChem CID
16683018
IUPAC Name
bis(2-hydroxypropanoyloxy)alumanyl 2-hydroxypropanoate
InChIKey
VXYADVIJALMOEQ-UHFFFAOYSA-K

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes FDA-recognized topical astringent; also used in OTC drugs

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Aluminum Lactate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Aluminum Lactate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =10 mg/kg bw/day oral: feed Mouse reproduction toxicity EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx
NOAEL =10 mg/kg bw/day oral: feed Mouse reproduction toxicity EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Aluminum Lactate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

1 property record from structured ingredient metadata.

mineral_clay
{"cas_number": "18917-91-4", "ingredient_class": "other", "chemical_formula": "Al lactate", "mineral_origin": "synthetic", "particle_size_range_um": "10-200", "surface_area_m2_per_g": "1-10", "crystal_structure": "amorphous", "color_appearance": "white", "opacity": "opaque", "refractive_index": "1.58", "oil_absorption_g_per_100g": "70-170", "water_absorption_capacity": "low", "surface_charge_at_pH…

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
Carcinogen Classification
Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468).
Source: Toxin and Toxin Target Database (T3DB)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Astringent Deodorizer pH regulating agent

Expert Verdict

Expert safety assessment and concern-level summary for Aluminum Lactate.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Aluminum Lactate by CAS number or substance name.

Studies
2
Lowest NOAEL
10 mg/kg bw/day
Highest NOAEL
10 mg/kg bw/day
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx

Known Synonyms

Propanoic acid, 2-hydroxy-, aluminum complex Aluminum, tris(2-hydroxypropanoate-O1,O2)- Aluminum, tris(2-hydroxypropanoato-O1,O2)- aluminum tris(alpha-hydroxypropionate) Aluminum, tris(2-(hydroxy-kappaO)propanoato-kappaO)- Aluminum, tris[2-(hydroxy-.kappa.O)propanoato-.kappa.O]- Aluminum lactate (Al(O3C3H5)3) EINECS 242-670-9 Tris(2-hydroxypropanoato-O(sup 1),O(sup 2))aluminum Aluminium-(RS)-lactat Aluminium lacticum UNII-V797H4GG0Z aluminium trilactate tris(2-hydroxypropanoato)aluminum tris(lactato)aluminium tris[2-(hydroxy-kappaO)propanoato-kappaO]aluminium

Chemical Function

Astringent Deodorizer pH regulating agent

Regulatory Lists

Canada; Personal care; Substances in PCP - Canada (4/2014)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Aluminum Lactate safe in cosmetics?

Aluminum Lactate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Aluminum Lactate allowed in the EU?

Aluminum Lactate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Lactate do in cosmetics?

Aluminum Lactate functions as: Astringent, buffering agent, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 18917-91-4.

What is the NOAEL for Aluminum Lactate?

The NOAEL (No Observed Adverse Effect Level) for Aluminum Lactate is =10 mg/kg bw/day based on a reproduction toxicity study via oral: feed route in Mouse. A total of 2 study endpoints are available. Source: EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx.

Is Aluminum Lactate used outside cosmetics?

Aluminum Lactate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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