Is Allantoin Glycyrrhetinic Acid safe in cosmetics?
Allantoin Glycyrrhetinic Acid has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Allantoin Glycyrrhetinic Acid
INCI: ALLANTOIN GLYCYRRHETINIC ACID
Allantoin Glycyrrhetinic Acid (CAS 4572-09-2) is a cosmetic cosmetic ingredient functioning as Skin Conditioning (miscellaneous). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 4572-09-2 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning (miscellaneous)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid;(2,5-dioxoimidazolidin-4-yl)urea
InChIKey
PCWYUXROTNZZHR-IHMBCTQLSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel concluded safe (2010); glycyrrhetinic acid independently reviewed and found safe at ≤2% concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Allantoin Glycyrrhetinic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Allantoin Glycyrrhetinic Acid.
Chemical Function
Humectant
Softener and conditioner
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Allantoin Glycyrrhetinic Acid allowed in the EU?
Allantoin Glycyrrhetinic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Allantoin Glycyrrhetinic Acid do in cosmetics?
Allantoin Glycyrrhetinic Acid functions as: Skin Conditioning (miscellaneous). It is classified as a cosmetic ingredient in our database. CAS number: 4572-09-2.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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