Is Adenosine Phosphate safe in cosmetics?
Adenosine Phosphate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Adenosine Phosphate
Also known as: Adenosine 5'-phosphate, 5'-AMP, β-D-Adenosine 5'-phosphate, AMP (nucleotide), Acido 5'-adenilico (+14 more)
INCI: ADENOSINE PHOSPHATE
Adenosine Phosphate (CAS 61-19-8) is a cosmetic cosmetic ingredient functioning as Skin Conditioning Agent – Miscellaneous. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 61-19-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning Agent – Miscellaneous
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
InChIKey
UDMBCSSLTHHNCD-KQYNXXCUSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics. CIR Panel concluded safe as used (Final Report, Sept 2020). Drug products containing AMP were withdrawn per 21 CFR 216.24 (not safe/effective as vasodilator), but this does not affect cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Adenosine Phosphate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Adenosine Phosphate.
Known Synonyms
Adenosine 5'-phosphate
5'-AMP
β-D-Adenosine 5'-phosphate
AMP (nucleotide)
Acido 5'-adenilico
Adenosine monophosphate (AMP)
Adenosine-5-monophosphoric acid
Adenosine 5′-monophosphate
5′-AMP
4-26-00-03615
Adenosine 5'-monophosphoric acid
AMP (VAN)
BRN 0054612
EINECS 200-500-0
Ergadenylic acid
Myoston
NSC-20264
Muskeladenosin-phosphorsaeure
Muskeladenylsaeure
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
Canada; pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ADENOSINE PHOSPHATE
ChEMBL ID
CHEMBL752
Max Phase
4
Adverse Event Associations
7
Frequently Asked Questions
Is Adenosine Phosphate allowed in the EU?
Adenosine Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Adenosine Phosphate do in cosmetics?
Adenosine Phosphate functions as: Skin Conditioning Agent – Miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 61-19-8.
Is Adenosine Phosphate used outside cosmetics?
Adenosine Phosphate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Adenosine Phosphate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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