Is Acetyl SH-Heptapeptide-1 safe in cosmetics?
Acetyl SH-Heptapeptide-1 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Acetyl SH-Heptapeptide-1
INCI: ACETYL SH-HEPTAPEPTIDE-1
Acetyl SH-Heptapeptide-1 (CAS 1356845-72-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 1356845-72-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(4S)-4-[[2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-[[(1S)-1-carboxy-2-phenylethyl]amino]-5-oxopentanoic acid
InChIKey
ZXBJGVKYUXGMIU-WYPAPEJYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl SH-Heptapeptide-1.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl SH-Heptapeptide-1.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3617787
Frequently Asked Questions
Is Acetyl SH-Heptapeptide-1 allowed in the EU?
Acetyl SH-Heptapeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl SH-Heptapeptide-1 do in cosmetics?
Acetyl SH-Heptapeptide-1 functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 1356845-72-1.
Is Acetyl SH-Heptapeptide-1 used outside cosmetics?
Acetyl SH-Heptapeptide-1 also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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ACETALDEHYDE
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Fragrance
ACETOBACTER FERMENT EXTRACT FILTRATE
Good
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Deodorant
ACETOBACTER/ASPERGILLUS/LACTOBACILLUS/LEUCONOSTOC/PEDIOCOCCUS/SACCHAROMYCES/ZYGOSACCHAROMYCES/CITRUS UNSHIU FRUIT/CITRUS JAPONICA FRUIT/CITRUS JUNOS FRUIT/ APPLE FRUIT/BANANA FRUIT/PAPAYA FRUIT/ PYRUS SEROTINA FRUIT/ DIOSPYROS KAKI FRUIT/WATERMELON FRUIT/PEACH FRUIT/ PRUNUS MUME FRUIT/FIG FRUIT/CHAENOMELES SINENSIS FRUIT/ERIOBOTRYA JAPONICA FRUIT/APRICOT FRUIT/ ZIZYPHUS JUJUBA FRUIT/CUCURBITA MAXIMA FRUIT/CASTANEA CRENATA FRUIT/VITIS COIGNETIAE FRUIT/RASPBERRY FRUIT/MOMORDICA GROSVENORII FRUIT/LYCIUM CHINENSE FRUIT/GLYCINE MAX SEED/PHASEOLUS ANGULARIS SEED/CANAVALIA ENSIFORMIS SEED/RICE SEED/HORDEUM VULGARE SEED/COIX LACRYMA-JOBI MA-YUEN SEED/ECHINOCHLOA CRUS-GALLI SEED/SETARIA ITALICA SEED/MILLET SEED/HEMEROCALLIS FULVA FLOWER/CABBAGE LEAF/STEM/MORUS BOMBYCIS LEAF/PERILLA FRUTESCENS LEAF/IPOMOEA BATATAS ROOT/COLOCASIA ANTIQUORUM TUBER/DIOSCOREA BATATAS RHIZOME/IRIDEA LAMINARIOIDES/LAMINARIA JAPONICA/NEMACYSTUS DECIPIENS/UNDARIA PINNATIFIDA/RADISH ROOT/TURNIP ROOT/CARROT ROOT/ARCTIUM LAPPA ROOT/NELUMBO NUCIFERA RHIZOME/ONION BULB/LILIUM AURATUM BULB/LICORICE ROOT/SAGITTARIA TRIFOLIA ROOT/SESAME SEED/GINKGO BILOBA SEED/JUGLANS SUBCORDIFORMIS FRUIT/PANAX GINSENG SEED/ACTINIDIA POLYGAMA FRUIT/HYDNUM ERINACEUM FRUITING BODY/GRIFOLA FRONDOSA FRUITING BODY/PRUNUS SALICINA FRUIT/AKEBIA QUINATA FRUIT/CRATAEGUS CUNEATA FRUIT/CORNUS OFFICINALIS FRUIT/NEPHELIUM LONGANA FRUIT/HOUTTUYNIA CORDATA/ARTEMISIA PRINCEPS/SASA VEITCHII LEAF/GLECHOMA HEDERACEA/CHAMOMILLA RECUTITA FLOWER/EQUISETUM ARVENSE/CASSIA OBTUSIFOLIA SEED/TARAXACUM OFFICINALE/ISODON JAPONICUS/SAFFLOWER FLOWER/PLANTAGO ASIATICA/SMALLANTHUS SONCHIFOLIUS ROOT/GARLIC BULB/GINGER RHIZOME/BEET RHIZOME/POLYGONUM ODORATUM RHIZOME/TURMERIC RHIZOME/ACANTHOPANAX SIEBOLDIANUS ROOT/PINUS KORAIENSIS SEED/LENTINUS EDODES FRUITING BODY/AURICULARIA AURICULA/VITIS LABRUSCA FRUIT/HELIANTHUS TUBEROSUS TUBER FERMENT EXTRACT
Good
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Skin Conditioning
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