Is Acetyl Hexapeptide-37 safe in cosmetics?
Acetyl Hexapeptide-37 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Acetyl Hexapeptide-37
INCI: ACETYL HEXAPEPTIDE-37
Acetyl Hexapeptide-37 (CAS 1447824-16-9) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Hydrating (Aquaporin-3 booster — enhances water transport. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1447824-16-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Hydrating (Aquaporin-3 booster — enhances water transport from basal epidermis to stratum corneum)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S)-1-[2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide
InChIKey
WZUFKRTZHLMBTG-TUUVXOQKSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl Hexapeptide-37.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl Hexapeptide-37.
Frequently Asked Questions
Is Acetyl Hexapeptide-37 allowed in the EU?
Acetyl Hexapeptide-37 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Hexapeptide-37 do in cosmetics?
Acetyl Hexapeptide-37 functions as: Skin Conditioning, Hydrating (Aquaporin-3 booster — enhances water transport from basal epidermis to stratum corneum). It is classified as a cosmetic ingredient in our database. CAS number: 1447824-16-9.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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ACETALDEHYDE
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Fragrance
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