Is 4-Nitro-O-Phenylenediamine Sulfate safe in cosmetics?
4-Nitro-O-Phenylenediamine Sulfate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
4-Nitro-O-Phenylenediamine Sulfate
INCI: 4-NITRO-O-PHENYLENEDIAMINE SULFATE
4-Nitro-O-Phenylenediamine Sulfate (CAS 68239-82-7) is a cosmetic cosmetic ingredient functioning as Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 68239-82-7 →
Auto-generated CPSR Part A draft with source citations
Function
Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted; covered under same CIR assessment as parent compound
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Nitro-O-Phenylenediamine Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: Restricted. Max: 산화염모제에 2.0%. 기타 제품에는 사용금지
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for 4-Nitro-O-Phenylenediamine Sulfate.
Regulatory Flags
potential-allergen
Chemical Function
Dye
Frequently Asked Questions
Is 4-Nitro-O-Phenylenediamine Sulfate allowed in the EU?
4-Nitro-O-Phenylenediamine Sulfate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Nitro-O-Phenylenediamine Sulfate do in cosmetics?
4-Nitro-O-Phenylenediamine Sulfate functions as: Oxidative hair dye (salt form of parent compound 4-NOPD, CAS 99-56-9). It is classified as a cosmetic ingredient in our database. CAS number: 68239-82-7.
Compliance Tools
Check 4-Nitro-O-Phenylenediamine Sulfate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acid Blue 9
Excellent
Same category
Colorant, Hair Dyeing
Acid Blue 9 Aluminum Lake
Excellent
Same category
Colorant
Anthocyanins
Excellent
Same category
Colorant
Beta Vulgaris Extract
Excellent
Same category
Skin Conditioning, Colorant (betalain...
Beta Vulgaris Root Extract
Excellent
Same category
Skin Conditioning, Colorant (betanin/...
Beta Vulgaris Root Powder
Excellent
Same category
Skin conditioning, natural colorant, ...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
3-Ethylamino-P-Cresol Sulfate
Moderate
Chemical family
Softener and conditioner
4-Nitro-M-Phenylenediamine Sulfate
Poor
Chemical family
Hair dye (salt form)
Methyl Gluceth-10
Excellent
Chemical family
Humectant, moisturizing, skin conditi...
Is 4-Nitro-O-Phenylenediamine Sulfate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for 4-Nitro-O-Phenylenediamine Sulfate in your formulation.