NOAEL Studies Cosmetic Ingredient

4-Formyl-2-Methoxyphenyl Isobutyrate (Vanillin Isobutyrate) NOAEL Studies

INCI: 4-FORMYL-2-METHOXYPHENYL ISOBUTYRATE

CAS: 20665-85-4

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral subchronic; 6 weeks subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eadc8e4b0a7c65d1c602e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/18694/7/6/2?documentUUID=d6e4ac78-40b4-41da-81e1-a0afc13d4b4f; YEAR=2014; ORIGINAL_YEAR=2014; TOXICOLOGICAL_EFFECT=body weight and weight gain|clinical signs|food consumption and compound intake|mortality; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|mortality/survival; STUDY_GROUP=ECHA IUCLID:15832017:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4dfb14b81b3b847cef4efdefa56fce72
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier C55654RCNR UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H14O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C55654RCNR"}
openFDA substances FDA UNII substance identifier C55654RCNR UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H14O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C55654RCNR"}
openFDA substances FDA UNII substance identifier C55654RCNR UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H14O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C55654RCNR"}
openFDA substances FDA UNII substance identifier C55654RCNR UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H14O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C55654RCNR"}