NOAEL Studies Cosmetic Ingredient

2-Methyl 5-Cyclohexylpentanol NOAEL Studies

INCI: 2-METHYL 5-CYCLOHEXYLPENTANOL

CAS: 1141487-54-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 >2000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_1955; row=5133; data_type=In Vivo; mixture=Chemical; chemical_name=Cyclohexanepentanol, .beta.-methyl-; preferred_name=Cyclohexanepentanol, .beta.-methyl-; dtxsid=DTXSID20889273; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID20889273; source_file=acute_oral.xlsx
ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral subchronic (developmental); 39 days reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cbb7e4b0a7c65d227398; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/20318?documentUUID=de184c52-4163-47f2-9eb1-15e1d4d09ae0; YEAR=2008; ORIGINAL_YEAR=2008; STUDY_GROUP=ECHA IUCLID:15848371:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_b6641209de9fe073df429c0a22d275d6
ToxValDB_ECHA_IUCLID NOAEL =300 mg/kg bw/day Rat oral - developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab48e4b0a7c65d1b9a55; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/20318?documentUUID=de184c52-4163-47f2-9eb1-15e1d4d09ae0; YEAR=2008; ORIGINAL_YEAR=2008; STUDY_GROUP=ECHA IUCLID:15861730:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_164bf3eb1a71adee2c18a4c9deaabd7b
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =2.6 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15630896:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_44a2c69ec4ca3a1cbf425554e8449b21
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 460837ILID UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H24O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"460837ILID"}
openFDA substances FDA UNII substance identifier 460837ILID UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H24O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"460837ILID"}
openFDA substances FDA UNII substance identifier 460837ILID UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H24O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"460837ILID"}
openFDA substances FDA UNII substance identifier 460837ILID UNII - - - chemical {"approval_status":null,"molecular_formula":"C12H24O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"460837ILID"}