NOAEL Studies Cosmetic Ingredient

1-Hexyl 4,5-Diamino Pyrazole Sulfate NOAEL Studies

INCI: 1-HEXYL 4,5-DIAMINO PYRAZOLE SULFATE

CAS: 1361000-03-4

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOAEL =26 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead4be4b0a7c65d1c388b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/24024?documentUUID=ac287f54-74a4-4340-901f-57584c489707; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15836133:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7aa06592f431914cfead5c15ccb4345e
ToxValDB_ECHA_IUCLID NOAEL ~8 mg/kg bw/day Rat oral - developmental GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabdde4b0a7c65d1bc341; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/24024?documentUUID=ac287f54-74a4-4340-901f-57584c489707; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15820767:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4a29c44c673fee2dc4d51003632bf391
ToxValDB_ECHA_IUCLID NOAEL =5 mg/kg bw/day Rat oral subchronic; 90 days subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead4be4b0a7c65d1c3885; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/24024?documentUUID=ac287f54-74a4-4340-901f-57584c489707; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15835086:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ba7547f52b4f4d341e3e5ef23619eee8
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 9L2QOQ6WFH UNII - - - chemical {"approval_status":null,"molecular_formula":"2C9H18N4.H2O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"9L2QOQ6WFH"}
openFDA substances FDA UNII substance identifier 9L2QOQ6WFH UNII - - - chemical {"approval_status":null,"molecular_formula":"2C9H18N4.H2O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"9L2QOQ6WFH"}
openFDA substances FDA UNII substance identifier 9L2QOQ6WFH UNII - - - chemical {"approval_status":null,"molecular_formula":"2C9H18N4.H2O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"9L2QOQ6WFH"}
openFDA substances FDA UNII substance identifier 9L2QOQ6WFH UNII - - - chemical {"approval_status":null,"molecular_formula":"2C9H18N4.H2O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"9L2QOQ6WFH"}