Food Safety Substance
Hesperidin
Hesperidin is a food additive with PUBLISHED in the EU, FDA has no questions in the US, and data from 6 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | PUBLISHED | EU additive listing; Annex II entry |
| United States | FDA | FDA has no questions | GRAS notice |
EU Food Additive Status
EU Commission food-additive listing rows from eu_food_additives.
| Jurisdiction | E-number | Status | Type | Name | Note |
|---|---|---|---|---|---|
| European Union | E959 | PUBLISHED | substanceFAD | Neohesperidine DC | - |
EU Annex II Authorised Uses
Authorised additive rows and use conditions from EU Annex II tables.
| Jurisdiction | E-number | Name | INS | Policy item | Note |
|---|---|---|---|---|---|
| European Union | E959 | Neohesperidine DC | - | POL-FAD-IMPORT-3299 | - |
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 796 | Orange extract (85% hesperidin) | FDA has no questions | For use as an ingredient in flavored milk and imitation milk drinks, dry powdered milk mixtures (not reconstituted), yogurt, coconut beverages, cookies, cereal... | Scientific procedures | Ferrer HealthTech |
| United States | 901 | Glucosyl hesperidin | FDA has no questions | Intended for use as a source of antioxidants, a coloring adjunct, flavor enhancer, and flavoring agent and adjuvant in beverages and beverage bases, coffee and tea, hard candy and... | Scientific procedures | Hayashibara Co., Ltd. |
| United States | 902 | Neohesperidin dihydrochalcone | FDA has no questions | Intended for use as as a sweetener in sweet crackers; biscuits; cornbread, corn muffins, tortillas; other muffins, popovers; other quick breads; fruit juices (with and without... | Scientific procedures | HealthTech BioActives, S.L.U. |
| United States | 796 | Orange extract (85% hesperidin) | FDA has no questions (in PDF) | For use as an ingredient in flavored milk and imitation milk drinks, dry powdered milk mixtures (not reconstituted), yogurt, coconut beverages, cookies, cereal... | Scientific procedures | Ferrer HealthTech |
| United States | 901 | Glucosyl hesperidin | FDA has no questions (in PDF) | Intended for use as a source of antioxidants, a coloring adjunct, flavor enhancer, and flavoring agent and adjuvant in beverages and beverage bases, coffee and tea, hard candy and... | Scientific procedures | Hayashibara Co., Ltd. |
| United States | 902 | Neohesperidin dihydrochalcone | FDA has no questions (in PDF) | Intended for use as as a sweetener in sweet crackers; biscuits; cornbread, corn muffins, tortillas; other muffins, popovers; other quick breads; fruit juices (with and without... | Scientific procedures | HealthTech BioActives, S.L.U. |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Hesperidin used for in food?
Hesperidin appears in food-use rows as: Antioxidant.
Is Hesperidin safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: EFSA ADI <= 5 mg/kg bw/day. EU status evidence: PUBLISHED. US/FDA evidence: FDA has no questions.
What is the ADI for Hesperidin?
Hesperidin has this ADI/reference value in the food-safety tables: EFSA ADI <= 5 mg/kg bw/day. Source: EFSA FEEDAP 2011.
Is Hesperidin also used in cosmetics?
Hesperidin has a same-CAS cosmetics cross-reference: Hesperidin, EU status permitted.