Food Safety Substance
Ergothioneine
Ergothioneine is a food-safety substance with no EU additive status row found in the EU, FDA has no questions in the US, and data from 4 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 734 | Ergothioneine | FDA has no questions | For use as a nutrient supplement in cakes, cookies, pastries (including granola bars); coffee; tea; fruit drinks and ades; carbonated soft drinks; and candy containing chocolate... | Scientific procedures | Blue California |
| United States | 1191 | Ergothioneine produced by Escherichia coli BL-21 (DE3) expressing ergothioneine synthases from Schizosaccharomyces pombe | FDA has no questions | Intended for use as an ingredient in cakes, cookies, pastries (including granola bars); coffee; tea; fruit drinks and ades; carbonated soft drinks; and candy containing chocolate... | Scientific procedures | Shanghai EGT Synbio Group Co., LTD |
| United States | 1270 | L-ergothioneine produced by Escherichia coli K-12 MG1655 expressing enzymes from Neurospora crassa and Mycolicibacterium smegmatis MC2 155 | FDA has no questions | Intended for use as an ingredient at levels up to 150 mg/100 g in coffee, tea, fruit drinks and ades, carbonated soft drinks, sports and energy drinks, nutritional beverages... | Scientific procedures | Gene III Biotechnology Co., Ltd. |
| United States | 734 | Ergothioneine | FDA has no questions (in PDF) | For use as a nutrient supplement in cakes, cookies, pastries (including granola bars); coffee; tea; fruit drinks and ades; carbonated soft drinks; and candy containing chocolate... | Scientific procedures | Blue California |
| United States | 1191 | Ergothioneine produced by <i>Escherichia coli</i> BL-21 (DE3) expressing ergothioneine synthases from <i>Schizosaccharomyces pombe</i> | FDA has no questions (in PDF) | Intended for use as an ingredient in cakes, cookies, pastries (including granola bars); coffee; tea; fruit drinks and ades; carbonated soft drinks; and candy containing chocolate... | Scientific procedures | Shanghai EGT Synbio Group Co., LTD |
| United States | 1270 | L-ergothioneine produced by <i>Escherichia coli</i> K-12 MG1655 expressing enzymes from <i>Neurospora crassa</i> and <i>Mycolicibacterium smegmatis</i> MC2 155 | FDA has no questions (in PDF) | Intended for use as an ingredient at levels up to 150 mg/100 g in coffee, tea, fruit drinks and ades, carbonated soft drinks, sports and energy drinks, nutritional beverages... | Scientific procedures | Gene III Biotechnology Co., Ltd. |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Ergothioneine used for in food?
No specific food-use/function row was found for Ergothioneine in the rendered food-additive tables.
Is Ergothioneine safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. US/FDA evidence: FDA has no questions.
What is the ADI for Ergothioneine?
No ADI row was found for Ergothioneine in the rendered EFSA, food_substances, food_additives, or JECFA tables.
Is Ergothioneine also used in cosmetics?
Ergothioneine has a same-CAS cosmetics cross-reference: Ergothioneine, EU status permitted.