Also known as: Benzoic acid, 4-(1,1-dimethylethyl)-, 4-09-00-01884, BRN 0607545, EINECS 202-696-3, Kyselina p-terc.butylbenzoova (+1 more)
CAS 98-73-7
4-tert-Butylbenzoic acid (CAS 98-73-7) is a chemical substance with GHS signal word Danger; key hazard signal: H360F; H302; H372. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
4-tert-Butylbenzoic acid is prohibited in EU cosmetics but has active industrial GHS classifications (H360F, H302, H372).
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Repr. 1B; Acute Tox. 4; STOT RE 1 | H360F; H302; H372 | GHS08; GHS07 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| artificial_sweat; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.067 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 43Z7T3VN0R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43Z7T3VN0R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43Z7T3VN0R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43Z7T3VN0R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >1.9 | mg/L | LC50 | Inhalation | - | NTP ICE acute inhalation |
| =473 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
Showing 7 of 7 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-tert-butylbenzoic acid | 202-696-3 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
4-tert-Butylbenzoic acid (CAS 98-73-7) is classified under EU CLP Annex VI as Repr. 1B; Acute Tox. 4; STOT RE 1 with signal word Danger. Hazard statements: H360F; H302; H372. Source: EU CLP Annex VI (ECHA).
4-tert-Butylbenzoic acid has 7 NOAEL studies in the database. The lowest reported value is 0.067 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
4-tert-Butylbenzoic acid appears on 5 regulatory/inventory lists including banned; Europe; Personal care, detected; Europe; Other direct contact consumer goods, air; detected; emissions; Europe; Other direct contact consumer goods, and 2 more. Source: EPA CPDat.
Yes, 4-tert-Butylbenzoic acid is also indexed as a cosmetic ingredient under the name 4-T-Butylbenzoic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
4-tert-Butylbenzoic acid is prohibited in EU cosmetics but has active industrial GHS classifications (H360F, H302, H372).
4-tert-Butylbenzoic acid also appears in cosmetics, pharmaceutical databases.