What is the NOAEL for Basic Orange 31?
Basic Orange 31 has 99 NOAEL studies in the database. The lowest reported value is O1JIQ710E2 UNII. Source: openFDA substances.
CAS 97404-02-9
Basic Orange 31 (CAS 97404-02-9) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.
Basic Orange 31 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H317, H318, H332, H411).
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care; restricted | European Commission | CosIng |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O1JIQ710E2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O1JIQ710E2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O1JIQ710E2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O1JIQ710E2 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 229 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =0.0011 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0011 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0011 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0011 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0013 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0013 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0013 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.0013 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =1 | % | NOAEL | dermal | - | SCCNFP_vision_codex |
| =1 | % | NOAEL | dermal | - | SCCNFP_vision_codex |
| =1 | % | NOAEL | dermal | - | SCCNFP_vision_codex |
| =1 | % | NOAEL | dermal | - | SCCNFP_vision_codex |
| =15 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =15 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =15 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =15 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =15 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =15 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =15 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =15 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =18 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =18 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =18 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =18 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =18 | mg/kg | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =18 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =53 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =53 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =53 | mg/kg bw | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =53 | mg/kg bw | NOAEL | dermal | rat | SCCNFP_vision_codex |
| =53 | mg/kg bw/day | NOAEL | oral | - | SCCNFP_vision_codex |
| =53 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
Showing 50 of 99 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-[(4-aminophenyl)azo]-1,3-dimethyl-1H-imidazolium chloride | 306-764-4 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1452/11 | 13-14 December 2011 | safe | 1.0% | sensitisation potential; secondary amine; nitrosamine <50ppb |
| SCCS/1419/10 | 14 December 2010 | insufficient data | - | impurity characterisation and genotoxicity data incomplete |
Same-CAS cosmetic ingredient record for cross-vertical context.
Basic Orange 31 has 99 NOAEL studies in the database. The lowest reported value is O1JIQ710E2 UNII. Source: openFDA substances.
Basic Orange 31 appears on 3 regulatory/inventory lists including children; Europe; Personal care, Europe; Personal care - hair coloring, Europe; Personal care; restricted. Source: EPA CPDat.
Yes, Basic Orange 31 is also indexed as a cosmetic ingredient under the name Basic Orange 31. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Basic Orange 31 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H317, H318, H332, H411).
Basic Orange 31 also appears in cosmetics databases.